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Improvement in advanced Alzheimer’s disease following high-dose psilocybin

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Re: Improvement in advanced Alzheimer’s disease following high-dose psilocybin

#151

Post by thin_carapace »

new-treatment wrote: post #87
trumpdong wrote: post #16

Psilocybin is one of those things we don't even know the full effects of because the government had a hysterical fit and completely banned it because people who took it were more likely to oppose the Vietnam War.

>>the government had a hysterical fit and completely banned it because people who took it were more likely to oppose the Vietnam War. If you are to believe the Brave New World ( https://en.wikipedia.org/wiki/Brave_New_World ) worldview of Huxley (who topically was on loads of LSD himself), you'd think the government would want to flood the public with psychedelics -- low to zero toxicity, allows people to zone out, n…

I don't believe the effects of huxleys fictional soma are overly comparable to strong psychedelics. for a closer comparison see cannabis and its widespread legalization. legal cannabis does result in the intended effect of people questioning things less. proliferation of strong psychedelics is more likely to cause mass psychosis than it is to achieve anything positive for the common man. and from big brothers perspective, stoned workers are more productive than psychotic ones.

Re: Improvement in advanced Alzheimer’s disease following high-dose psilocybin

#152

Post by wouldbecouldbe »

LoganDark wrote: post #102
wouldbecouldbe wrote: post #89

Earlier quoted context omitted.

shame, same with mushrooms?

Cannot say the same for psilocybin. Far as I can tell, I majorly overdosed the first time, because I fainted, hit my head and had to go to the hospital for staples. Around a week later I took the same dose again (the rest of what I had) to help process the trauma. (It did help. I of course avoided the situation that made me faint the first time) I'd want to try psilocybin again sometime; it's quite a bit more expensi…

Wow, yeah maybe cool off things for a while. You have some wild experiences. We have legal truffles in NL, come and visit, they are not so expensive here. But maybe trip with a guide for a while.

Re: Improvement in advanced Alzheimer’s disease following high-dose psilocybin

#153

Post by yieldcrv »

JumpCrisscross wrote: post #118
bilsbie wrote: post #49

Earlier quoted context omitted.

What’s exciting though is that this administration recently signed an executive order directing the agency to speed up the development and approval process for psychedelics.

> this administration recently signed an executive order directing the agency to speed up the development and approval process for psychedelics Can’t the President directly unschedule it?

No, because Congress proscribed an extremely convoluted process for this specific thing

So skipping it is a nuclear option that will not survive the courts

Re: Improvement in advanced Alzheimer’s disease following high-dose psilocybin

#154

Post by LoganDark »

wouldbecouldbe wrote: post #152
LoganDark wrote: post #102

Earlier quoted context omitted.

Cannot say the same for psilocybin. Far as I can tell, I majorly overdosed the first time, because I fainted, hit my head and had to go to the hospital for staples. Around a week later I took the same dose again (the rest of what I had) to help process the trauma. (It did help. I of course avoided the situation that made me faint the first time) I'd want to try psilocybin again sometime; it's quite a bit more expensi…

Wow, yeah maybe cool off things for a while. You have some wild experiences. We have legal truffles in NL, come and visit, they are not so expensive here. But maybe trip with a guide for a while.

It's been years since then. At the end of the day it's FAFO.

That fainting episode wouldn't have been prevented with a guide unless they followed me into the bathroom, since for some reason the smell is what caused me to faint. (I found this out during the second time when going near the bathroom made me feel fainty -- I am glad I figured out what it was so that I could avoid it. It would've sucked to conclude that I can't have psilocybin at all, or something)

I will actually end up visiting the NL for other reasons eventually, so I might look into magic truffles :)

Re: Improvement in advanced Alzheimer’s disease following high-dose psilocybin

#155

Post by ProllyInfamous »

trio8453 wrote: post #74
ProllyInfamous wrote: post #61

Earlier quoted context omitted.

>upper-esophageal sphincter dysfunction If you've never read a Pulitzer Prize Winner, Confederacy of Dunces would be a personally-relatable disaster (to start with; it's great). >Psychedelics are one of my favorite classes of drug. Your initial description of usage was probably a bit wreckless , but I do maintain that most people would probably benefit from a single (or few) psilocybin experiences (preferably an init…

Microdosing has very limited evidence to support it, and even mode widely varying claims for what it supposedly helps with.

It helps me not be an asshole.

Datapoint: one.

----

https://en.wikipedia.org/wiki/A_Confederacy_of_Dunces>

Re: Improvement in advanced Alzheimer’s disease following high-dose psilocybin

#157

Post by lostmsu »

wouldbecouldbe wrote: post #76
ozgrakkurt wrote: post #46

Earlier quoted context omitted.

> When you take it, you understand To be fair, this is not how medical research is done.

You fortunately don't need medical research in learning how to live your life and experience meaning. It's great if we have therapies that help people and get a proper scientific stamp. Yet we can also discover the benefits for ourselves before that stamp is given.

> You fortunately don't need medical research in learning how to live your life and experience meaning.

Here I'd disagree with you. I do need to know if you become happier because you become dumber due to brain damage or for some other magical reason. So far I haven't seen any evidence contrary to the dumber explanation.

Re: Improvement in advanced Alzheimer’s disease following high-dose psilocybin

#158

Post by lostmsu »

Aurornis wrote: post #13

This case report is being shared widely across social media but it’s full of red flags from top to bottom. It’s a case report (n=1) that a group of 3 people from Brazil wrote up and pushed into the publishing world. The report is full of big words and tables, but barely says anything more than the abstract: It’s basically “an 80 year old Japanese women received mushrooms and was better afterward” expanded with as muc…

This article at least "gratifies one's intellectual curiosity" as it shows that even among HN audience there's plenty of relatively dumb people. 200+ in this case. 200 people who not only fail to see a pile of horseshit for what it is, but in their ignorance spread it bringing even greater harm to people who are less equipped to critically review information like this.

Re: Improvement in advanced Alzheimer’s disease following high-dose psilocybin

#159

Post by make3 »

elzbardico wrote: post #128
make3 wrote: post #125

Earlier quoted context omitted.

why take cocaine when you can get your doctor to prescribe Adderall to you

The elites get the finest Colombian artisan cocaine. Comparing it to aderall is like comparing 25 years Japanese malt to cheap Johnny Walker black.

Pharmaceuticals are not a question of taste like alcohol and food, they're strictly a matter of purity, stability and toxicity, which is clearly better supported by being produced by an industrialized country with sometimes hundreds of career chemical engineers running the show in a billion-dollar company with processes etc., & who have liability for lawsuits worth hundreds of millions of dollars if they put anything remotely close to the shit recreational drugs are cut with, like horse tranqualizer and deworming agents and whatnot.

The best elites can dream of is pharmaceutical levels, but even the most pure illegal stuff comes from a production line that's isolated from the rule of law and from transparency and liability and also likely from actual professionals, so it's likely still more toxic than it needs to.

The real "advantage" of cocaine is mostly that the molecule has an inherently stronger euphoric effect, I would assume (I've never taken it), also making it a worse therapeutic if you want to actually do a better job vs just feel "high".

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