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Metabolic and cellular differences between sedentary and active individuals

howardluksmd.substack.com

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Re: Metabolic and cellular differences between sedentary and active individuals

#151

Earlier quoted context omitted.

never understood the physical exercise is fun thing. i do it but it's just pure pain. i guess people are wired differently.

Finding enjoyment in things that are difficult or painful is the probably highest impact quality of life lesson you can learn.

that sounds like masochism, or some kind of rationalization.

Re: Metabolic and cellular differences between sedentary and active individuals

#152

Earlier quoted context omitted.

Um, wlcouldnt you walk wkth your kids?

toddlers, so not happening. plus as a kid, i absolutely hated exercise-walking with my parents. it made me despise walking for ~20 years.

Huh, ai mean both my sisters walk for like an hour a day with their toddlers most days with good weather. So idk, different strokes for different filks I guess

Re: Metabolic and cellular differences between sedentary and active individuals

#153

A lot of people in the comments are expressing curiosity about "ideal" amounts of exercise to avoid these sorts of problems. I have a real-life friend whose hobby is studying this stuff. His recommendations boil down to: - 1/week 20 minutes HIIT: 5 minutes warmup, 3x(2 minutes high intensity + 3 minutes low intensity) blocks. - 1/week strength training focused on large muscle groups. - 12,000 steps per day walking (H…

Isn't 12k steps like 6 miles? I could plausibly jog that much, but to walk it every day seems like a huge time commitment.

this is why i love walkable cities! You don’t need to “schedule” time every week to meet basic fitness goals. You just walk to the subway, bus stop, etc. Walk to lunch. Walk to the park, Walk to buy groceries, etc.

For those living in suburbs, I hear dogs can be a good excuse to walk more. :)

Re: Metabolic and cellular differences between sedentary and active individuals

#154

A lot of people in the comments are expressing curiosity about "ideal" amounts of exercise to avoid these sorts of problems. I have a real-life friend whose hobby is studying this stuff. His recommendations boil down to: - 1/week 20 minutes HIIT: 5 minutes warmup, 3x(2 minutes high intensity + 3 minutes low intensity) blocks. - 1/week strength training focused on large muscle groups. - 12,000 steps per day walking (H…

12000 steps is around 10km. And takes around 2-2.5 hours of walking. So I say it is total baloney. Only very few people can do that amount of walking daily. Plus after you do a 2+ hour walk your body next day needs time to recuperate. As an added note it could be utterly boring to walk the same route again and again. Rather do 6 km slow running 2 or 3 times a week (of course if you are not severely overweight). You c…

It’s not 2 hours of walking nonstop. Walking to the toilet counts. So does walking to the bus, the grocery store, to lunch, etc.

I think it’s doable if you live in a very walkable city. I routinely hit about 11k steps most days of the week. Some days less of course…like if i’m sore from a workout or just feeling sedentary.

Re: Metabolic and cellular differences between sedentary and active individuals

#155

Earlier quoted context omitted.

toddlers, so not happening. plus as a kid, i absolutely hated exercise-walking with my parents. it made me despise walking for ~20 years.

Huh, ai mean both my sisters walk for like an hour a day with their toddlers most days with good weather. So idk, different strokes for different filks I guess

not possible in my case

Re: Metabolic and cellular differences between sedentary and active individuals

#156
post #90

Earlier quoted context omitted.

I’ve been chronically ill for 11 years now. I wasn’t really exercising basically at all for 8 of them then I started walking 3 years ago and jogging 1 year ago and cycling 6 months ago. My VO2 max was 52 at age 24. 40 when tested a year later after becoming sick. I had it retested a year ago and it was 36.5. But I ran a 5:59 mile a month ago so it is very likely higher now. But I haven’t been able to get it retested…

If you want to know your VO2 Max then you can do a Cooper Test for free at your local school running track. That won't be as precise as a metabolic lab test with a breathing mask but close enough. https://en.wikipedia.org/wiki/Cooper_test

Yeah I did that a few months ago and did 1.54 miles in 12 minutes. I think I could do more now. But that is so different from gas measured Vo2 max it makes me think it isn’t that accurate for my condition. Like perhaps my body is compensating

Re: Metabolic and cellular differences between sedentary and active individuals

#157
post #40

Earlier quoted context omitted.

I’ve been chronically ill for 11 years now. I wasn’t really exercising basically at all for 8 of them then I started walking 3 years ago and jogging 1 year ago and cycling 6 months ago. My VO2 max was 52 at age 24. 40 when tested a year later after becoming sick. I had it retested a year ago and it was 36.5. But I ran a 5:59 mile a month ago so it is very likely higher now. But I haven’t been able to get it retested…

What illness if you don't mind me asking?

fluoroquinolone toxicity and mast cell disorder

complete nightmare to live with

like I have permanent tendinopathy and muscles even still to this day lock up easily probably from mitochondrial dysfunction which would be explained by multiple lab findings I had like a really low lactate threshold compared to normal for my age

and I react to everything I eat with throat swelling eventually and constantly have to switch foods

nothing works long term I’ve tried everything I react to medications if taken long enough as well

Re: Metabolic and cellular differences between sedentary and active individuals

#158

A lot of people in the comments are expressing curiosity about "ideal" amounts of exercise to avoid these sorts of problems. I have a real-life friend whose hobby is studying this stuff. His recommendations boil down to: - 1/week 20 minutes HIIT: 5 minutes warmup, 3x(2 minutes high intensity + 3 minutes low intensity) blocks. - 1/week strength training focused on large muscle groups. - 12,000 steps per day walking (H…

Isn't 12k steps like 6 miles? I could plausibly jog that much, but to walk it every day seems like a huge time commitment.

Then jog that much in zone 2. I’ve done exactly that, replaced 10K steps a day with < 30 mins jogs if I can’t hit the target for any reason (I work from home so it happens quite often unless I’m mindful about moving).

Re: Metabolic and cellular differences between sedentary and active individuals

#159

Between this and http://myticker.com (posted recently), I want to share a theory of mine: 1) the internet is mostly made up of spaces where the median opinion is vanishingly rare among actual humans. 2) the median internet opinion is that of a person who is deep into the topic they're writing about. The net result is that for most topics, you will feel moderate to severe anxiety about being "behind" about what you sh…

Don't feel bad about your VO2 max, the baseline and ceiling are largely genetic. Most people can only bump VO2 max by about 10-15% even with absurd training regimens. Same goes with many of the markers people track - you can control them to an extent, but some people just have high blood pressure or poor lipid profiles and thus need intervention.

Thanks for saying that. Even when I ran every day — with the occasional VO2max sprint day —, my Apple Watch never placed me anywhere but Below Average for VO2max. It was disheartening. Some of these metrics actually put you off training.
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