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Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

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Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#151

Post by 8note »

inglor_cz wrote: post #34
chris_wot wrote: post #25

Earlier quoted context omitted.

Amazing how badly the United States is regressing. Literally measles is making a comeback due to idiots like RFK.

This is now a global problem. The guy who started it, Andrew Wakefield, is British, and we have long had antivaxxers in Europe too. Prior to Covid, the antivaxx scene was vaguely left-and-green oriented, biomoms, vegans and other "very natural" people; you would expect them to vote for Greens or even more alternative parties. This changed abruptly and now the antivaxx scene is mostly rightwing, but the common base is…

i dont think its nearly so transparent. its easy to be recommended and read some viewpoints, but very technical and hard to be recommended others.

with radical information transparency, id expect both views to be equally easy to parse and to be recommended both, in which case the choice would be obvious to everyone, or at least they could very well describe their risk tolerance to different risks, or laziness, for why they made a certain choice.

i expect im not up to date on all the vaccines i should be, but its on laziness rather than gwtting bad information. ...also a lack of information on which ones i should have.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#152

Post by dotnet00 »

boxerab wrote: post #136
JumpCrisscross wrote: post #104

Earlier quoted context omitted.

Maybe we’re seeing selection pressure against those prone to addictive cycles of social-media influenced misinformation? Like, anti-vaxers died at higher rates in Covid [1]. This will continue across disease outbreaks, particularly ones for which we have near-comprehensive vaccines like measles. And given antivax sensibility is heritable (through parenting, not genes), one would expect this to stabilize the populatio…

very few people are against vaccines per se, they are just against *unsafe* vaccines. "anti-vax" is a term used to dismiss dissident without having to deal with their arguments i.e an ad hominem. As an analogy, if I object to high levels of mercury in fish, am I anti-fish? or anti-poisonous-fish ?

For just being "against *unsafe* vaccines" they sure tend to have some very weird ideas of what a safe vaccine is.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#153

Post by 8note »

boxerab wrote: post #97
vhcr wrote: post #92

Earlier quoted context omitted.

> Is there a net positive benefit to this shot? Yes https://ourworldindata.org/hpv-vaccination-world-can-elimina...

Doesn't answer the question. Other vaccines, for example DTP, have been shown to cause higher long term mortality rate over those who didn't get it. https://bmjopen.bmj.com/content/2/3/e000707

> Setting High-mortality countries in Africa and Asia.

this reads like a big grain of salt on the results.

from the paper, its more specific that girls who got the DTP vaccine and also not another vaccine afterwards have a higher mortality rate.

but also that its wildly different by location

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#155

Post by duffpkg »

This article headline is a gross abuse of the conclusions of the actual study which is here: https://www.eurosurveillance.org/content/10.2807/1560-7917.E...

This site is full of people perfectly capable of reading most studies. I would much rather see these links go to studies than endless clickbait articles about studies.

The conclusion of the study show that about 30% of the women in the study from 2017-2014 tested positive for one of several types of HPV infection. This does appear to be a reduction from an earlier 2013 study but the earlier study was by different authors with different methodology so gauging the scale of the reduction is not straightforward. My opinion is that a safe conclusion of the study is that HPV prevalence has not increased.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#156

Post by pitpatagain »

ars wrote: post #127
pitpatagain wrote: post #119

Earlier quoted context omitted.

That's because other strains weren't covered by the original vaccines: Strains 16 and 18 were the high risk strains covered in the 2008 roll-out, the roll-out to young girls of the broader vaccine covering other high risk strains didn't start until 2017. “In 2017, one of the first birth cohorts of women in Denmark who were HPV-vaccinated as teenage girls in 2008 reached the screening age of 23 years,” Nonboe explaine…

The other strains were not covered because they were not common. Now they are. Which means some new strain will become common. Is there any data on how quickly/easily new strains show up? I assume it's not as fast as cold/flu, but if it is people will need a vaccine yearly, and that's not realistic.

Also after some research about rate of change: It's extremely slow.

HPV is a double-stranded DNA virus with very high replication fidelity. The emergence of types like 16 and 18 happened hundreds of thousands of years ago.

I did know it was quite slow but not just how slow. Very long term vaccine efficacy is expected.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#157

Post by passing_by_and »

perihelions wrote: post #29

By way of contrast, America's current top "doctor" organized a class-action lawsuit against the HPV vaccine. https://www.reuters.com/business/healthcare-pharmaceuticals/... ( "Kennedy played key role in Gardasil vaccine case against Merck" ) > "Details of the Gardasil litigation show how Kennedy took action beyond sowing doubt about the safety and efficacy of vaccines in the court of public opinion and helped build a…

[flagged]

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#158

Post by respondo2134 »

Fomite wrote: post #48
riggsdk wrote: post #40

Earlier quoted context omitted.

In Denmark you can. I was in my mid thirties when I went to my doctor to ask them to prescribe it. Before each shot I would go to the pharmacy and buy one dose and go to the doctor to have them administer it for me (if I wanted to). At that time I think it was free for teenage girls, now it's free for teenage boys as well.

The evolution of who gets HPV vaccines is really interesting. At first it was young women, as vaccinating young men had a very marginal decrease in cervical cancer rates via indirect protection (which itself is a function of how many young women are vaccinated). Then as HPV infection was linked to more cancers, vaccinating young men crossed the cost-effectiveness thresholds many governments use. Vaccinating older pop…

it's not just the cost of the vaccine roll-out though, you need test on your target demo and since these are healthy people the bar is very high. If the demographic (like males over 45) shows very little involvement in the infection vectors then testing might fail the cost-effectiveness, not the delivery of the vaccine.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#159

Post by pimlottc »

loeg wrote: post #140
LorenPechtel wrote: post #111

Earlier quoted context omitted.

It's not approved for those over 45. (AFIAK, simply because so few people in that age group would have risk without having had prior exposure. Basically only those who had divorced or lost their long time partner.)

It's not "recommended" but your PCP can prescribe it off-label if you ask -- just ask.

The issue is getting it covered by insurance. Otherwise it can cost over $1,000 for the full course of shots.

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#160

Post by toast0 »

Obscurity4340 wrote: post #44
comrade1234 wrote: post #36

Earlier quoted context omitted.

Any way to test for previous exposure? I'd be pretty surprised if I didn't already have antibodies. I suppose it doesn't matter though.

Not sure but theres zero downside to getting it

Information from the CDC [1], indicates Adverse Reactions are similar to administration of a placebo, which is not zero. Any vaccine administration has potential for negative adverse reactions, it's reasonable not to get a vaccine if you judge the upside is not worth the downside, even if the downside is small.

The CDC says:

> Like all medical interventions, vaccines can have some side effects.

[1] https://www.cdc.gov/vaccines/vpd/hpv/hcp/recommendations.htm...

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