151–160 of 176 posts
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And if diet alone isn't getting you to a healthy weight, the GLP-1 drugs are miraculously effective and don't have a lot of downsides aside from cost.
Is way too early to know about any downsides of these drugs. I’m afraid too many people are gonna find out the downsides when it’s too late.
Ascorbic is not a correct name of a compound. Should be 'ascorbic acid' or Vitamin C. Such sloppiness cast doubt on accuracy of the whole review.
Read a little further... it's specifically called ascorbic acid and vitamin C. He probably just wanted to save space within the table.
It kind of gross to call ascorbic acid like that, as someone who studied chemistry I'm revolted.
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Realistically you can maybe get another couple year from what I can tell. Is it worth it? I'd focus more on qulalitiy of your life. not everyone will die of something all these can help with, the obese person I used to know enjoyed eating - and we can now say in hindsight that diet changes would not have helped him live longer.
leading a healthy active lifestyle DOES improve the quality of your life. Getting diabetes and injecting yourself daily with insulin is not a quality life. Having trouble walking or playing with your grandkids because one is too fat and has ruined their joints is also not quality. Having a miserable last 10-20 years of life due to a stroke is also not quality. These things don’t mysteriously happen. :) Being able to…
What's striking about "anti-ageing" research is how it keeps circling back to the same boring truths: don’t smoke, keep your weight down, move often, sleep properly, keep blood pressure and cholesterol in check, and go easy on the booze. If something makes an overweight, sedentary smoker hit 100, then it’s a miracle drug. Please let me know if/when you've seen that drug...
In the absence of actually lengthening the telomeres, everything falls short in the anti-aging department. Most lifestyle habits contribute to shorting the telomeres as little as possible, which guarantees good health no matter the age, but still aging, albeit slower. Given the current technology trajectory, many people including me, think that we are very close to totally stopping aging, and even reversing it.
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The majority is gaining literal years of healthy lifespan. It would take a lot of damage to even approach this gain for the average person. Like we used to do very invasive and impactful gastric surgery to try and get weight loss and nobody batted an eye, no?
> The majority is gaining literal years of healthy lifespan You’re saying this like it’s true already. Let’s give it 10 years.
Because it is true already? You take an obese person who has a lower quality of life because of their obesity and give them a drug that helps them lose that weight and keep it if, they're literally gaining function and a higher quality of life from it. Today.
> Fast for short intervals regularly, and longer fasts as they feel good to you. You can effectively do this every day if you just eat once per day. When I was properly obese, this technique resulted in rapid weight loss. Zero exercise was required to see results, which was good at the time because the not eating part was about all I could handle. Being in a fasted state is as close as you can get to actually reversi…
While autophagy does correlate with fasting and some studies link it to health markers, it should be noted that it usually takes at least 18 hours of continued fasting to even start and only goes into full swing after 48 to 72 hours. It is also an extreme cell response that is associated with high levels of cellular stress, which might have understudied long term detrimental effects. A simple calorie reduction either…
People love their probiotic pills but I'm not convinced - the amount of beneficial microbes is measured at bottling or production and who knows how many survive by the time they get to you. Not to mention how many survive into your gut once consumed.
Homemade sauerkraut or natto though? Pretty much guaranteed to be teeming with the stuff. And your grandparents and their parents were probably eating it their whole lives. It's a whole forgotten art / science that is thankfully making a comeback.
Anecdotally (obviously sample size of 1 so big grain of salt here) every person in my personal life who I saw live to a super long age and also maintain good mental fitness followed what you are saying above plus made their own fermented food into their elderly years.
At the worst it does nothing for longevity and you end up with more unique tasty food for yourself and your friends :-D
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There is a difference between dying at 40 and dying at 80. Also, I see no reason why people couldn't live for, say, 200 years or even indefinitely. I think it is an engineering problem that can be solved and I wish we as humanity allocated more attention and resources into solving this particular problem. Especially as it concerns all of us. Solving suffering and then solving mortality sounds like a good project to m…
Philosophically there is no difference. The gun to your head is infinity, 40 years has no meaning.
* different people can have different philosophies on life
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> I think there are some proper human trials happening but the jury is still out. That's exactly my point. No one really knows the risk that they are taking.
People are still getting nerve damage from too much vitamin B6 in energy drinks and vitamin supplements, and that's a well known and widely taken vitamin. The idea that you can take experimental drugs your entire life at little risk is optimistic.
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> The majority is gaining literal years of healthy lifespan You’re saying this like it’s true already. Let’s give it 10 years.
> You’re saying this like it’s true already Because it is true already? You take an obese person who has a lower quality of life because of their obesity and give them a drug that helps them lose that weight and keep it if, they're literally gaining function and a higher quality of life from it. Today.
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leading a healthy active lifestyle DOES improve the quality of your life. Getting diabetes and injecting yourself daily with insulin is not a quality life. Having trouble walking or playing with your grandkids because one is too fat and has ruined their joints is also not quality. Having a miserable last 10-20 years of life due to a stroke is also not quality. These things don’t mysteriously happen. :) Being able to…
I don't want to be pedantic but these things do, in fact, 'mysteriously' happen to completely 'healthy' people.
But if i have routine labs done and find out i’m prediabetic, i have 2 choices. I could continue eating cookies every day like my mom did and not exercise, or i could make lifestyle changes and take metformin proactively.
Similarly with high blood pressure, and more. That alone addresses like 80% of modern ailments. Things get more tricky when we consider complex conditions like migraines, etc, which you have much less agency over as a person.