Earlier quoted context omitted.
I believe most people are not notability adversely affected by sugar and a small subset of the population, like myself, are acutely affected. The former does not invalidate the latter. Sarah Wilson of “I quit sugar” fame started off with a zero sugar crusade then later ameliorated her advice in an apparent effort to generalize her advice for a wider audience. I think advice should be tailored by conditioning on what…
Thank you, I initially came here to post a comment disencouraging sugar based on my anecdotal experience. It's indeed weird that people I know don't report the same immediate, acute, negative effects that I experience upon sugar consumption. Until now it never occurred to me my experience might not be universal. Curiously I have ADHD too. Maybe there is a link? In my experience an apple = a bar of chocolate, has the…
If you scroll through my previous message history I cover this topic quite a bit, you can also email me. In general terms, I think hEDS is far more common than doctors do, and is likely caused by TNXB SNPs. TNXB SPNs are overlooked because these are too common to cause the 'rare' condition - but if you drop the prior assumption of rarity then a very different picture is painted. It appears to me that the only difference between hEDS and far more common Generalized Joint Hypermobility (GJH) is severity and the stochastic diagnosis that this difference causes. The prior assumption of rarity has informed the diagnostic test so the diagnostic tests reproduce this assumption and in my view have an extremely high false negative rate. If using other proxy stats like the rate of hypermobility in Long Covid from the work of Dr Jessica Eccles it's pretty clear that that prior assumption of rarity is wildly inaccurate. I was able to figure this out because I have experience as an applied researcher and machine learning, having spent half a lifetime reading papers I've developed a bit of a nose for the sorts of mistakes that academic researchers tend to make.