Earlier quoted context omitted.
What would you do if you found out you would? (I ask as someone whose great-grandfather, great-uncle, and grandfather all had Parkinson’s.) I’ve avoided any testing because, as far as I know, there’s nothing preventative to be done. I’d love to hear otherwise. I’ve broached the subject with my last two primary care physicians and both advised that there was no point in knowing.
Pick up a nicotine addiction. Seriously, it has long been understood that people who smoke have dramatically lower levels of parkinsons. It comes from the neuroprotective properties of nicotine. You don't have to become a smoker, you could theoretically use any of the other forms (vape, gum, patch)
Significant breakthrough in search for Parkinson's biomarker
151–160 of 196 posts
Re: Significant breakthrough in search for Parkinson's biomarker
#152Re: Significant breakthrough in search for Parkinson's biomarker
#153Re: Significant breakthrough in search for Parkinson's biomarker
#154Earlier quoted context omitted.
Pick up a nicotine addiction. Seriously, it has long been understood that people who smoke have dramatically lower levels of parkinsons. It comes from the neuroprotective properties of nicotine. You don't have to become a smoker, you could theoretically use any of the other forms (vape, gum, patch)
Curious if you have any links to support lower incidence of Parkinsons for smokers. I found this, which states that nicotine does not slow the disease once started: https://www.michaeljfox.org/news/nicotine-patch-not-benefici...
https://www.sciencedirect.com/science/article/abs/pii/S01674...
There have also been numerous studies that have found that starting nicotine once symptoms begin is too late, with little or no effect. It is hypothesized that there is some critical point that once crossed, nicotine no longer has an effect. Parkinsons is believed to slowly develop over years or decades, and nicotine stunts this early progression.
Re: Significant breakthrough in search for Parkinson's biomarker
#155For those living in the bay area, you should know that the groundwater in many areas is contaminated with TCE due to computer manufacturing industry which used it as a solvent. Dry cleaners are another common culprit of contamination to the groundwater. These groundwater plumes can extend for quite a large distance from the original site of contamination and seep into the first story of residences and buildings throu…
https://twitter.com/realEstateTrent/status/14378028033139220...
Re: Significant breakthrough in search for Parkinson's biomarker
#156Earlier quoted context omitted.
Certain pesticides are confirmed causes of Parkinsons. Don't remember which now, but could look it up.
No, none are "confirmed causes". There are mild associations between the use of certain pesticides and Parkinson's, but much lower than the overall genetic risk factors, and there's always the possibility of confounding factors in the studies.
Re: Significant breakthrough in search for Parkinson's biomarker
#157Earlier quoted context omitted.
That's the precise essence of why quackery is dangerous. People are searching for "every possible way that can help" and quackery can easily exploit that natural tendency. (I am not qualified to render any opinion on whether this specific protocol is quackery.)
The problem is the lack of incentives to take the “huh that’s interesting, but I don’t know if I can trust it because it’s published in a quack journal” … and ever reproduce the research and get it into more trusted more prestigious journals. There’s a reproducibility crisis in many fields of research, and medical research has multiple confounding factors, the “no prestige in just redoing the research”, lack of money…
Presumably, because the more prestigious journals declined to publish it.
Why did all of them decline to publish it? There was probably a reason. A paper being published in a quack journal does actually carry a signal about the quality of paper, IMO. No one turns down publishing in Cell or Neuron to publish in Donald's Journal o' Quackery and Crockpot Recipes.
Re: Significant breakthrough in search for Parkinson's biomarker
#158Interesting that big flu outbreaks cause a long term spike in Parkinson's - how much more will be traced back to the impact of viruses? Saw that come up as a worry around Covid, seems the loss of smell/taste is a commonality with Parkison. We will not know for a decade or two though, but these biomarkers might help accelerate measuring the impact.
It’s very plausible in 10-20 years or so. Studies found a massive increase in acting out of dreams amongst those who had Covid. This acting out of dreams is a very strong precursor to Parkinson’s. According to this, 80% of people with it get Parkinson’s within 20 years. https://www.salon.com/2023/04/24/long-parkinsons/
Re: Significant breakthrough in search for Parkinson's biomarker
#159For those living in the bay area, you should know that the groundwater in many areas is contaminated with TCE due to computer manufacturing industry which used it as a solvent. Dry cleaners are another common culprit of contamination to the groundwater. These groundwater plumes can extend for quite a large distance from the original site of contamination and seep into the first story of residences and buildings throu…
Re: Significant breakthrough in search for Parkinson's biomarker
#160Earlier quoted context omitted.
> Parkinson's has many forms and many causes. A lot of my family were farmers. I've had close relatives die with severe Parkinsons, primarily those that farmed their whole life. Their theory was that it was really exposure to a lot of toxic farm chemicals. I can imagine Parkinsons turning out to be several different conditions with similar symptoms.
In The Netherlands we have A LOT of farmers with parkinsons. Most, if not all cases seem to be related to Roundup/Glyphosate.