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Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

reuters.com

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Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#151

There is a terrifying whistleblower interview from a Berlin elderly home, about the events after the vaccination. Of 31 patients who were vaccinated 8 died within 14 day, another 11 are in decline. https://2020news.de/en/whistleblower-from-berlin-nursing-hom... Similar reports came out of Sweden and other countries, after the first report. https://2020news.de/auch-in-schweden-sterben-die-alten-mensc... There are many…

This is most likely going to get flagged into oblivion, for those who come later it's a list of supposed cases where there are mass deaths after the COVID-19 vaccination.

Of course 15 million people have received the vaccine in the UK, so any sudden deaths even at the level of 0.01% would be quite noticeable by now.

Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#152
post #137
post #98

Earlier quoted context omitted.

There was time. I work in manufacturing, we plan factories years in advance of manufacturing start. Abandoned biotech factory cost is a drop in the ocean compared to weekly lockdown cost. Why countries failed here? If I would do such crap professionally, shelves of electronics stores would be empty.

There were/are multiple vaccine candidates with different production needs. How do you decide which factories to build? I think there are a lot of unrealistic expectations when it comes to these highly sophisticated vaccines. It's not comparable to your average electronics product.

> How do you decide which factories to build?

All of them. Or at least all of the different kinds of factories (mRNA, vector, live vaccine) for the most promising candidates. If there is a shortage of something, force production, apply imminent domain, force cooperation. War against Corona should be handled like a war, not like a toilet paper shortage.

Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#153
post #17

As I understand, for example in Europe Pfizer is producing vaccines in single factory and not in sufficient number. Why production doesn't happen in more places? Couldn't they sell license to other European pharmaceutical companies to produce it? Is production process so unique it can't be replicated in other places?

first of all, while Pfizer might just be producing at their factory in Belgium, that vaccine is produced in multiple factories in Germany by Biontech, most notably in Marburg (which is going to become Biontech's largest production site) And secondly, 'just' producing the vaccine isn't the only bottleneck. Currently the biggest bottleneck seem to be two molecules that are produced earlier on in the production-process,…

Good point with upstream availability issues. I never really looked those up, simply because I have zero idea how vaccine manufacturing works. Until now, I only focused on the downstream side, everything after manufacturing. And I don't like what I see on that end, especially in Germany.

It is almost like the world at are is getting a crash course in supply chain management. One could have asked experts on that before, sure, but why bother when local politians need credits for their election campaigns, right?

Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#154

Earlier quoted context omitted.

Some American factories are export restricted, Pfizer has set up production in the US which is cleared for export as they didn’t took any government funding for those production lines. Israel is getting most of their doses from US factories not EU ones.

And pays more than 10x as much per dose.

And that really doesn't matter compared to the cost of locking down a country and the lives saved by quicker vaccination.

Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#155

Earlier quoted context omitted.

downtote. This is anti semitic. A fringe minority rioted. It's far too simplistic to say that covid is simply being ignored.

why am i getting downvotes? The hareidim ignore lockdown because their way of life is more important to them even then some deaths. Difficult for an outsider to understand. As for being anti vax, the vaccine is practically being forced down their throats. There will be a pushback (not that i agree). (and yes there could be more compliance, this is not the forum).

Israeli here. Their way of life is not threatened by a vaccine nor by lockdown. No more than any other citizen of israel. Their leadership still has ghetto mentality and sees the state as their enemy, so they always choose to go against it while crying Nazis. It doesn't matter that these so called Nazis are jews themselves.

This is the sort of mentality that 2000 years of diaspora creates. Their way of life is now defined by choosing to be the outcast, by wearing outcast uniform, by fearing and hating those that don't wear the uniform.

Their leadership is just aweful.

Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#156

Israel feels like the only nation taking the importance and urgency of vaccination seriously. Here in Europe, articles are coming out complaining that the slow vaccination could be harming the economy which, well, fucking duh. ( https://www.brusselstimes.com/news/belgium-all-news/154626/c... ) Fast rollout. Involve pharmacies. Involve the army. Distribute widely and efficiently. Prepare for months before the vaccine…

The thing I don't get is why not try to mass manufacture the candidates before we know they are effective? It seems the work of what drug to make was done really quickly, and most of the time is spent in the trials, and then mass production. Maybe I missed it, but you'd think with something so devastating we'd just make a bunch of candidates, get them out to the clinics for storage, and as soon as we thought a given…

That is exactly what happened -- governments around the world paid for pre-approval manufacturing and the pharma industry has spent the last 6-8 months ramping up production. That's the reason we have any supplies at the moment.

The truth is just that mass-manufacturing of a brand new vaccine is a hard problem. The fact that we're only a couple months from the very start of vaccinations and the world is already nearing 200 million doses delivered is, frankly, amazing. The only problem is that due to the severity of the crisis we wish we had a magic wand that gave us 10x the supply right this instant.

The good news is that manufacturing continues to ramp up dramatically. It just feels like it's slow because we're all so eager for it to improve. If you look at the month-on-month growth, though, it's clearly ramping up fast: https://covidvax.live/

Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#157

Earlier quoted context omitted.

Unfortunately the EU still communicates there is no problem with the procurement but only with evil pharmaceutical companies not delivering as promised. There will not be any remorse. It really must hurt them that even the heavily criticized politicians Johnson, Netanyahu and Trump did a much better job with procurement than the EU.

The EU messed up but they are at least publicly owning up to some of the blame (finally): https://www.theguardian.com/world/2021/feb/10/ursula-von-der...

Well, really owning up to a mistake that will cost a few tens of thousands of lives would at least be a resignation.

Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#158
post #81

Earlier quoted context omitted.

Are you saying EU specifically tried to ban export to UK while export to the rest of the world is ok?

There is/was a contract dispute between the EU and AstraZeneca regarding supply of the Oxford-AstraZeneca vaccine. The EU wanted AstraZeneca to supply additional vaccine from it's UK-based factories, which are already contracted to supply the UK. The export registration requirements (not an export ban ) are, at least in part, in response to this dispute. https://www.theguardian.com/business/2021/jan/30/lawyers-dis...

Well, the contract with the EU included the UK factory(ies) as a (potential?) supplier to the EU.

UK signed the contracts slightly earlier and jump-started the programme by issuing an emergency approval a few weeks earlier than the regular approval by the EMA.

And above all, it seems despite all efforts of coordination and treaties (COVAX), almost all players (except Norway) are playing the auction game and hoarding.

This is a global pandemic and these "selfish" actions will have global effects :(

Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#159

There is a terrifying whistleblower interview from a Berlin elderly home, about the events after the vaccination. Of 31 patients who were vaccinated 8 died within 14 day, another 11 are in decline. https://2020news.de/en/whistleblower-from-berlin-nursing-hom... Similar reports came out of Sweden and other countries, after the first report. https://2020news.de/auch-in-schweden-sterben-die-alten-mensc... There are many…

These links appear to be, to use a technical term, Bullshit. From my admittedly bad German skills, I can see that the level of reporting here is terrible, completely focused on the single issue of "vaccines are bad", and probably will lead to the deaths of a lot of people.

Re: Israeli study finds 94% drop in symptomatic Covid-19 cases with Pfizer vaccine

#160
post #149
post #137

Earlier quoted context omitted.

There were/are multiple vaccine candidates with different production needs. How do you decide which factories to build? I think there are a lot of unrealistic expectations when it comes to these highly sophisticated vaccines. It's not comparable to your average electronics product.

Build 10 damn factories if needed. For biotech it is cheap - hundreds of millions, not billion range as for semiconductor. As a reminder - saving Lufthansa alone consumed €9B: https://www.bbc.com/news/business-52801131

Sure, and it is the mney that is building these factories? You need people, you need certification. And that is once the building and equipment is their. No dea why people always ignore the time aspect of supply chains. Having more capacity in 4 months isn't any good now. Nor is it n 4 months when existing capacites are suffcient in 4 months anyway.

And they are using new site, Biontech in Marburg (a reporposed existing facility if memory serves well), Sanofi will be ready in summer to produce the Biontech vaccine as well. These things take time, rushing them is never a good idea.

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