Earlier quoted context omitted.
The biggest problem is blind trust in the system. This is how we get stories of people trusting GPS directions and driving straight into lakes. Taking a few minutes to zoom out and check the actual maps in terrain view would save most people on these journeys.
That wouldn't necessarily help in the given example. Desert stream beds often look very similar to roads on satellite and furthermore, data rates are abysmal in most of these places. You frequently can't load much beyond the cached basemap to check.
If you don't have data access then Google Maps routing won't help much either. It all comes down to offline/hard maps, situational awareness, and basic wayfinding to get through these areas safely.
EDIT: what are people disagreeing with here?