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Intermittent fasting from dawn to sunset induces anticancer response

pubmed.ncbi.nlm.nih.gov

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Re: Intermittent fasting from dawn to sunset induces anticancer response

#151

Post by ahefner »

hombre_fatal wrote: post #131
colinmhayes wrote: post #113

Earlier quoted context omitted.

Drip coffee is horrible, so I understand wanting sugar. I moved to black by buying a mocha pot and aeropress. It's a whole different coffee experience, milk and sugar not necessary.

I have every coffee making gimmick from the chemex to the aeropress and I guarantee you would fail a blind test on which one is which, or if the cups of coffee are even different. I mean, what exactly is the mechanical difference of putting hot water through coffee grounds and a filter that differs when you do it in an aeropress vs. a dripper? And you think you're tasting enough of a difference to say one is horrible…

I can definitely taste the difference brewing the same coffee via a french press versus my old fashioned percolator on the stove, and not on account of loose coffee grounds. This may be an extreme comparison as a percolator is possibly the worst way to brew coffee. Convenient, though. It makes little difference to me, I usually drink it black over ice.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#152

Post by rconti »

Barrin92 wrote: post #102
ronyeh wrote: post #32

Earlier quoted context omitted.

I think intermittent fasting is easier to implement for the average person. It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). It's difficult to tell someone you can eat 3 meals but no more than 1500 calories in total. Once I start eating, I don't want to stop (until I'm full). But the point at which I'm full is way beyond my calorie limit if I am eating…

>It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). If eating is part of your social or work life as it is for most people then not really. Or you're going to sit there sipping water while your family or your colleagues eat or have drinks which is miserable

It just depends entirely on your mentality. Some folks are much better at moderating than abstaining, others are the opposite. If you tell me to drink 10% less, I virtually cannot do it. If you tell me to never touch a drop of alcohol again in my life, I just say "bummer!" and get on with it.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#154

Post by sorennielsen »

theshrike79 wrote: post #138

"Dawn to Sunset" laughs nervously in Scandinavian So we can't eat anything in the summer, as the sun doesn't really go down? :) On the other hand, we can gorge ourselves during winter.

I had the exact same thought and then checked where the authors was from.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#155

Post by jonmc12 »

"The Switch", by James Clement, is a great roundup of fasting and other longevity-related behaviors. It's a synthesis of hundreds of research papers, with an emphasis of the 2016 discovery of the mTor switch that triggers autophagy in cells. The findings in the NIH paper seem pretty consistent with the overview of the research. More specifically, mortality from obesity and cancer drastically fall when: a) insulin and iGF-1 are suppressed, and b) mTor pathway (and autophagy) is triggered somewhat regularly.

The Fasting Mimicking Diet is a well studied diet that mimics the effects of fasting while eating 800-1200 calories per day and abstaining from protein (https://docs.google.com/spreadsheets/d/1_f-UhsloOxvLbNLgyAou...

Dave Feldman's (engineer turned citizen scientist) independent research into the impact of low-carb, high-fat diets is also inspirational to learn first-hand how a diet can effect your body. He's replicated experiments of how several dietary approaches, including fasting, affect the lab measurement of cholesterol levels. He's been able to reproduce findings on his own body, with small sample sizes of other dieters. He's even proposed a Lipid Energy Model to describe how fats distribute energy to cells in a way that matches the data he's collected. https://cholesterolcode.com/model/

Reading enough of this research, I start to think about context-dependent metabolic pathways that can be triggered with inputs as simple as varied macronutrients. It feels like a very meaningful frame to interpret research about diet and longevity.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#156

Post by blastro »

ketzo wrote: post #65
optymizer wrote: post #56

Anecdata: I have followed IF with a 1100 calorie deficit per day by only eating 1200 calories at dinner for 3 months. This translated to more than 1kg weight loss per week, pretty reliably. Overall I lost 17kg. I adjusted the TDEE and calorie values as needed to maintain the weight loss speed. The weight loss was extremely fast, but so was the rate at which I lost lean mass. This makes sense, as I didn't exercise muc…

Yeah, fasting is one of those ""health fads"" that really does seem to work miraculously... for some people. For some, it's just nothing; for some, it's miserable. Kind of bizarre how different our metabolisms can be.

yes metabolisms can be very different

Re: Intermittent fasting from dawn to sunset induces anticancer response

#157

Post by blastro »

DoreenMichele wrote: post #146
hombre_fatal wrote: post #139

Earlier quoted context omitted.

Also frees up your entire body from being constantly bathed in hormones like insulin.

I sort of think of it like "maintenance downtime." It was my son that first suggested to me it helps by freeing up immune cells and letting them concentrate on other things for a bit and I think that makes a lot of sense. I also suspect that dropping your blood sugar levels low enough, long enough helps starve some invaders. We are bigger than the bacteria in our system. We can survive for a bit without those resourc…

you make good points!

Re: Intermittent fasting from dawn to sunset induces anticancer response

#159

Post by [deleted] »

Barrin92 wrote: post #102
ronyeh wrote: post #32

Earlier quoted context omitted.

I think intermittent fasting is easier to implement for the average person. It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). It's difficult to tell someone you can eat 3 meals but no more than 1500 calories in total. Once I start eating, I don't want to stop (until I'm full). But the point at which I'm full is way beyond my calorie limit if I am eating…

>It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). If eating is part of your social or work life as it is for most people then not really. Or you're going to sit there sipping water while your family or your colleagues eat or have drinks which is miserable

[deleted]

Re: Intermittent fasting from dawn to sunset induces anticancer response

#160

Post by noja »

Barrin92 wrote: post #102
ronyeh wrote: post #32

Earlier quoted context omitted.

I think intermittent fasting is easier to implement for the average person. It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). It's difficult to tell someone you can eat 3 meals but no more than 1500 calories in total. Once I start eating, I don't want to stop (until I'm full). But the point at which I'm full is way beyond my calorie limit if I am eating…

>It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). If eating is part of your social or work life as it is for most people then not really. Or you're going to sit there sipping water while your family or your colleagues eat or have drinks which is miserable

Exactly, but let's be realistic here: all that other eating between and all those meals that are not social meals - they can go.
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