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Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

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Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#151
post #89

Earlier quoted context omitted.

You are right and it is no secret: - 40% of US Americans are B12 deficient https://www.livekindly.co/b12-deficiency-genetic-makeup/#:~:... . - 42% are Vitamin D deficient: https://www.cantonmercy.org/healthchat/42-percent-of-america... . - up to 50% are Magnesium deficient: https://www.sciencedaily.com/releases/2018/02/180226122548.h... - 10 - 20% of women are iron deficient: https://www.aafp.org/afp/2007/0301/p671.h…

I wouldn't be surprised if quarantine is leading to an historic spike in D deficiency.

I haven't been this tan in years! It's been really easy to go outside for a walk, I hope to keep it up in the coming years...

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#152

Earlier quoted context omitted.

I just Googled "vitamins lead to higher all cause mortality." First result: https://www.sciencedaily.com/releases/2011/10/111010173019.h... >After adjustment, use of multivitamins, vitamin B6, folic acid, iron, magnesium, zinc and copper, were all associated with increased risk of death in the study population. The top three links showed association between beta carotene supplementation and risk of death. A little fu…

The risk of excessive iron is known and not new If you read that link you'll see the findings for iron and calcium were replicated. (Not to mention this article is basically referencing a different article which is somewhere else, so we're missing the context) The B12 issue, as the own article mentions, is not necessarily connected to a dietary excess consumption > Participants within the highest quartile of vitamin…

>The risk of excessive iron is known and not new

OK so that's one mineral they called out from a long list that includes multi vitamins, B6, and magnesium, very common recommendations. What about the rest?

Point taken about the B12 study.

What about https://www.medscape.org/viewarticle/751462#:~:text=The%20us...

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#153
post #16

I wonder, when I see stories about studies about treating patients with basic nutrients and vitamins, if a root-cause to consider is that our standard diets are so deprived of essential vitamins and minerals that "treating" someone with what they have been missing causes the body to simply function the way it's supposed to. I haven't read the full study but if it takes into account what someone's diet was prior to th…

It's sampling bias. Plenty of people eat healthy diets in America. But if you only look at people who get very sick with COVID, they're far more likely to eat a bad diet

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#154

> Patients were administered oral vitamin D3 1000 IU OD I've seen multiple sources say that 1000 IU of vit D is usually insufficient to boost levels, with suggestions of up to 5000 a day. My mothers doctor put her up to 2000 a day because 1000 did nothing to her levels, which were already low.

How did the doctor know her vitamin levels were low? I once asked a doctor if the vitamins in our body can be measured, and he said it can't be done, is not something you can measure.

Blood test, had it done myself and found low levels of B12 & D, for which I took initially large doses and now take over the counter supplements

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#155

Earlier quoted context omitted.

I eye-rolled at that guidance too, until a loved one was diagnosed out of the blue with stage-2 melanoma. It's terrifying. Don't screw around with sun protection. Despite what the internet says, people who work outside get it too.

I don't doubt that skin cancer happens. I doubt that vitamin D supplementation is delivering all the benefits that sunshine does.

and you're basing this on....

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#156
post #7
post #2

N=43 (17 given vitamins vs 26 not) Highlights: "Significantly fewer DMB patients than controls required initiation of oxygen therapy subsequently throughout their hospitalization (17.6% vs 61.5%, P=0.006)." "DMB combination in older COVID-19 patients was associated with a significant reduction in proportion of patients with clinical deterioration requiring oxygen support and/or intensive care support. This study supp…

The number of people in the study is too small to really make much in the way of definitive conclusions. But it is certainly enough that a larger study should occur. In the meantime, since vitamins are cheap and not dangerous at these doses, it seems a reasonable measure to go ahead and take them. They might help, there's weak evidence to suggest that they might, and they shouldn't hurt. However, it's important not t…

If we're going to call out one of those three vitamins for overdose potential, it's the magnesium you should be calling out, not the vitamin D. Accidental vitamin D overdose seems to be a non-issue, almost (but not quite) entirely theoretical. Clinically-significant doses of magnesium can have real effects on the body, though, even in the "safe range"; it affects your heart fairly strongly, for instance, and needs to be in balance with some other nutrients. Even if you are in fact in need of magnesium supplementation, you can trigger some heart issues if you supplement magnesium without the other nutrients you need to go with it. This won't happen to most people, but I'd guess it's a 3-4 more orders of magnitude serious concern than vitamin D overdose.

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#157

Earlier quoted context omitted.

And perhaps most of our conclusions are wrong (not b/c of our poor reasoning, but b/c we are misled by poor studies)! Remember that half of all research papers are probably wrong and most of medical research is wrong, according to John Ioannidis: "Why Most Published Research Findings Are False" by John P. A. Ioannidis: https://journals.plos.org/plosmedicine/article?id=10.1371/jo... Lighter reading on this topic: "Lie…

I think this is wrong: Ioannidis's major point is that a lot of studies in medicine are underpowered (a similar issue to the replication crisis in psychology), leading to a lot of false positives. But there is no reason to think that this would be the case for a study that finds a vitamin deficiency in the population. We can expect no issues with p-hacking or garden of forking paths just because there is no place for…

How kind of you to summarize Ioannidis' studies in a single sentence and then dismiss them based on your undoubtedly highly-educated and data-supported opinions, saving readers the drudgery of clicking a link, browsing a noted paper and possibility gaining some enlightenment and ease-of-mind.

Perhaps you should write a study about argumentation?

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#158

Earlier quoted context omitted.

You are right and it is no secret: - 40% of US Americans are B12 deficient https://www.livekindly.co/b12-deficiency-genetic-makeup/#:~:... . - 42% are Vitamin D deficient: https://www.cantonmercy.org/healthchat/42-percent-of-america... . - up to 50% are Magnesium deficient: https://www.sciencedaily.com/releases/2018/02/180226122548.h... - 10 - 20% of women are iron deficient: https://www.aafp.org/afp/2007/0301/p671.h…

I've always wondered about this deficiency thing. How is it defined, and does it make any sense to claim that such a large part of the population is deficient? Shouldn't that be considered "normal" (excluding the truly pathological cases), as opposed to "above-average"?

Similarly with drinking 3 litres of water a day, or you're dehydrated. How did our ancestors get 3 litres of water a day? Seems like the first person ever who wasn't dehydrated was born around 1985.

Re: Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients

#159
post #132

Earlier quoted context omitted.

I suspect it's exactly the opposite. During quarantine, you have far fewer people spending most of their waking hours in huge concrete coffins. How many people even get to see the sun during a typical workday, much less spend time in direct sunlight?

In big cities like NYC people get sunlight during their commute, but get no sunlight when cooped up in a small apartment. Vitamin D deficiency has been long proven to inhibit proper functioning of the immune system, but this isn't widely known which is a huge failure of the press and the authorities.

it's also specifically very good for respiratory diseases apparently.
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