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FDA just cleared a $20 Covid-19 antibody test

coronachecktest.com

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Re: FDA just cleared a $20 Covid-19 antibody test

#151
post #5

That's an antibody test, not an RNA test. Quite a different thing. It will only detect an infection when you have an immune response already. It will not if you don't. RNA tests can detect the virus even if it doesn't turn a person diseased.

Are you a doctor? If not, why are you commenting on things you have no expertise on?

Are you a HN mod?

Am I an irony dealer?

Re: FDA just cleared a $20 Covid-19 antibody test

#152
post #105

Earlier quoted context omitted.

I think its almost certain that if it were possible to be re-infected (at least in short timescales), it would have happened by now, somewhere.

There have been reports, but it’s not to my knowledge clear whether the people who’ve tested positive after being considered recovered were experiencing something else, like a false positive before/after, or weren’t in fact fully recovered.

Running theories so far are that those were relapses, not reinfections.

Re: FDA just cleared a $20 Covid-19 antibody test

#153
post #57

Earlier quoted context omitted.

There’s not good evidence of that. There have been cases of people testing negative then positive again but that doesn’t mean they had cleared the virus and got reinfected. It more likely means they had a false negative. (E.g. I have a friend in hospital right now with COVID-19 that has had four tests, one positive, two negative, then one positive again, all tests within the space of four days.) It also can be the ca…

> It also can be the case if you are immune compromised that you may clear the virus through good luck, drugs, and your innate immune response. uh, how? Perhaps this is tangential, but it's important that anyone who is immunocompromised takes this seriously. Don't just think you'll be ok with a bit of luck. If you are immunocompromised your immune response is by definition weak and we have no working therapeutics. Ye…

I don’t think you read my comment in the context of what it was replying too. It was a response to someone saying people can get reinfected. The reports of this appears not to the case for the reasons I and others explained (false positives/negatives). I speculate it might possibly happen for real though in the case of immune compromised people who are lucky enough to survive, but due to being immune compromised do not mount a proper adaptive response. Thus develop no antibodies and and thus are able to be reinfected. Obviously that would be rare. (But so are these case reports that are driving these rumors of “reinfection” overall.)

Not really sure how you read that as somehow advocating immune compromised people do not need to take this seriously.

Re: FDA just cleared a $20 Covid-19 antibody test

#155
post #48

This is an antibody test which will only be positive days after the onset of symptoms. This is principally useful for several purposes: 1. Figuring out who to isolate in hospitals if the RNA test isn't available in sufficient quantity 2. Understanding who has already recovered from COVID-19 and is thus immune with all that implies in terms of inability to spread the disease and reduced need for PPE 3. Enabling us to…

Bear in mind in relation to immunity -- "Positive results may be due to past or present infection with non-SARS-CoV-2 coronavirus strains, such as coronavirus HKU1, NL63, OC43, or 229E."

This preprint explores, in part, cross-reactivity for a similar test and found it to negligible: https://www.medrxiv.org/content/10.1101/2020.03.17.20037713v...

Re: FDA just cleared a $20 Covid-19 antibody test

#156

Earlier quoted context omitted.

If that's true, it seems to me that it would imply that this whole thing is a mass hysteria, at least as applied to the U.S. population, since Seattle would have looked like Italy a month ago.

There's absolutely no evidence to suggest that happened.

Suggest what happened

Re: FDA just cleared a $20 Covid-19 antibody test

#157
post #140
post #132

Earlier quoted context omitted.

Some health professional floated the theory that kids aren’t getting it as much as the rest of the population because they’ve recently been hammered with all the coronaviruses at daycare. I’m hoping this is true, since it suggests new parents are mostly OK too.

I keep searching for animal studies on this and come up empty - all I can find is some studies on serological cross response when testing people for SARS exposure. Vaccines are obviously the best bet, but I wonder whether deliberately exposing the healthy to common cold Coronavirus might improve herd immunity against this Coronavirus. E.g. maybe in late summer it can be used to forestall a second wave of Coronavirus…

Do it like we did smallpox? Worth a shot...

Re: FDA just cleared a $20 Covid-19 antibody test

#158
post #26

Ummm, guys. Unsubstantiated claims along with a website clearly designed to sell... Screams scam to me. If it is real, wait to hear about it from the CDC or other reputable source.

https://www.businesswire.com/news/home/20200318005814/en/

No expert but if it was a scam wouldn't they want to sell directly to end users?

Re: FDA just cleared a $20 Covid-19 antibody test

#159

Not fda reviewed, they don’t even have permission to ship it yet, per their own sales page. Probably violating the master merchant agreement of every card network by selling it at this point, so proceed with caution.

https://www.businesswire.com/news/home/20200318005814/en/

Re: FDA just cleared a $20 Covid-19 antibody test

#160

Earlier quoted context omitted.

This is an antibody test which will only be positive days after the onset of symptoms. This isn't really what your Twitter link says. That links says: "Both IgM & IgG (those are two different kinds of antibodies, with IgA being a third) were low or undetectable at day 0, but increased by day 5 in nearly all patients (N=16)" -- Reports strongly indicate there are many infected people who are asymptomatic after five da…

Turn around time is mostly due to shipping samples to outside labs, in addition to outside labs lacking automation.

But that doesn't change the current situation.

Even you could change that, just cost would make this approach very useful.

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