Live data from Hacker News

Psilocybin found safe for consumption in largest ever controlled study

independent.co.uk

151–160 of 236 posts

Re: Psilocybin found safe for consumption in largest ever controlled study

#151
post #111

Recently tried shrooms for the first time and was a bit underwhelmed, but not sure if I'm micro-dosing or what. Tried the regular variety and some other allegedly Thai shrooms, which definitely had a stronger effect. I tried a few stems at first, and then ramped up the dosage with slightly more 'visuals', but it's like I have to eat a whole handful or just let my body learn to process it or something.

From what I've heard (no real scientific data to back this) the stems contain very little psylocibin. And the dosage for mushrooms is surprisingly high. For run of the mill strains, I believe 3.5 grams is considered a standard dose. Which is still not a blast you off the planet amount, but enough to experience visual distortions and euphoria.

On some strains 3.5 grams is a serious therapeutic dose requiring a sitter.

My last trip was about this much with another 1.5 set aside but I was blasted out of time and space and opted not to re-up.

It all depends on the strain.

Re: Psilocybin found safe for consumption in largest ever controlled study

#152
post #21

I'm gonna sound really cliched but I have become really fascinated with Psychedelics thanks to the Joe Rogan podcast. I wouldn't say I am depressed but as someone who doesn't drink, smoke, drugs or take caffeine. I really want to try them. The fact that mushrooms have been used by shamans all around the world since neolithic times, is truly fascinating. I hope to try them at some point although at the moment I have b…

I’d steer you toward kava kava as a legal and otc way to change your mind and emotions for the better or more open. Also St. John’s wort.

kava is okay as a replacement for a muscle relaxer or alcohol if you want to drink dirt that makes you pee like a race horse, but, I wouldn’t put it anywhere in the same league therapeutically as psychedelics.

Re: Psilocybin found safe for consumption in largest ever controlled study

#153
post #21

Earlier quoted context omitted.

I’d steer you toward kava kava as a legal and otc way to change your mind and emotions for the better or more open. Also St. John’s wort.

After googling, it appears that kava causes liver damage, thanks but no thanks

Deeper googling might lead you to the conclusion that it’s totally safe. Anyway it’s not a psychedelic.

Re: Psilocybin found safe for consumption in largest ever controlled study

#154
post #25
post #21

Earlier quoted context omitted.

I’d steer you toward kava kava as a legal and otc way to change your mind and emotions for the better or more open. Also St. John’s wort.

What source would you recommend? I've tried some name-brand kava tea and it didn't seem to do much.

If you want to get high, by the bulk kava powder from Amazon, but it tastes absolutely terrible.

For day to day use try the Yogi Tea with kava in it. It has cardamom so actually tastes good. The dose is very low so you’d need 3+ teabags to feel anything.

Re: Psilocybin found safe for consumption in largest ever controlled study

#155

Counter-anecdote: I've experimented with this stuff extensively in various settings and have known many other people who did, and in my experience it's unequivocally bullshit. Here's what happens. First, any given trip alleviates depression for about a month or two. That makes sense to me in a sense that the word "trip" isn't a coincidence-- a really fun intense vacation in a foreign country also alleviates depressio…

Third path: It's a fun way to pass the time once in a while.

Fourth path: You learn what you need from it, that the world is just various inputs into your brain and gives you perspective to slow down.

As an aside, your post is full of negativity. I hope you get the help you need somewhere.

Re: Psilocybin found safe for consumption in largest ever controlled study

#158
post #150

Earlier quoted context omitted.

First of all, there is a wide delta of difference between taking these substances recreationally and in a clinical setting. Any clinician involved with these trials is not going to equivocate their use in treating depression with your weekend in the woods with your friends. Second if we are talking recreationally I have met many, many people on a third path there: the understanding that psychedelics offer a beautiful…

> "I believe your cynicism has sliced off only a portion of the truth here and tilted focus in the wrong directions." I think his cynicism is completely warranted considering how many people are starting to view psychedelics as a panacea. Do psychedelics offer an experience that could be part of, or even a spark a greater shift? Sure. Could psychedelics provide temporary relief from things like depression and anxiety…

I'm so sorry you are being downvoted. The current enthusiasm for psychedelics is making it very difficult to talk publicly about all the dimensions of a highly nuanced topic.

Re: Psilocybin found safe for consumption in largest ever controlled study

#159

Counter-anecdote: I've experimented with this stuff extensively in various settings and have known many other people who did, and in my experience it's unequivocally bullshit. Here's what happens. First, any given trip alleviates depression for about a month or two. That makes sense to me in a sense that the word "trip" isn't a coincidence-- a really fun intense vacation in a foreign country also alleviates depressio…

That's a hell of a generalization from an anecdote.

Re: Psilocybin found safe for consumption in largest ever controlled study

#160

Counter-anecdote: I've experimented with this stuff extensively in various settings and have known many other people who did, and in my experience it's unequivocally bullshit. Here's what happens. First, any given trip alleviates depression for about a month or two. That makes sense to me in a sense that the word "trip" isn't a coincidence-- a really fun intense vacation in a foreign country also alleviates depressio…

I mean, temporary alleviation of symptoms can be extremely valuable.

Think of how many people are on SSRIs that have mixed effectiveness, side-effects, and have to be taken daily. Then compare that with a treatment that you do once a month and whose main side-effect is a heightened sense of empathy. Even if it doesn't permanently get rid of depression and anxiety, and solve all of your underlying problems it's still a big step forward relative to the current state-of-the-art treatments.

I can speak to how nice it is to just feel fine for a while and get some respite from a constant feeling of fear and anxiety at everything. It's a world of difference, and could easily be the difference between someone not even being able to get out of bed, and actually taking a crack at doing things.

Post reply on HN