Earlier quoted context omitted.
There are plenty of in-memory database architectures that takes full advantage of fast random access offered by DRAMs. I think paper focuses on OS design which is still tied with assumption of slow disks.
In-memory databases are not economically scalable. To a first approximation, database volume is the integral of database throughput, so databases that require extreme I/O throughput also tend to require extremely high volumes of online data. Many typical sensor data models, which drive much of the need for high-throughput I/O, grow by petabytes per day so the multiple orders of magnitude difference in media cost make…
SAP HANA is widely used for very large data sets.