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How often do full-body MRIs find cancer?

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141–150 of 290 posts

Re: How often do full-body MRIs find cancer?

#141
Doctors absolutely hate the idea of people being checked for diseases. Every time someone comes out with a plan to detect cancer or prevent HIV, they start screeching.

“But what if the person would have died anyway without noticing they had cancer? Think of the shareholders. They would have paid for treatment for nothing”

Re: How often do full-body MRIs find cancer?

#142
post #135

Arguments against proactive MRI scanning always seem to have a whiff of status quo bias to them. Yes, right now MRIs are expensive and false positives are common, but if regular scans were widespread, it's likely this result in innovations that would drive down costs, improve accuracy, as well as producing a much larger corpus of data with which to guide diagnosis and reduce false positives. To use a software analogy…

There's a softer component to healthcare which is that people can overreact to medical results. If a doctor administers a scan, finds a handful of likely benign things but wants to administer another scan later on down the line, I'm probably much more likely to look for a second opinion that tells me to cut them out (even if it may not be medically necessary) than trust my doctor that "it's probably fine". It's proba…

No, this is more like disabling logging because people are concerned the server is going down.

“Don’t worry about it, I don’t think it’s a real issue so we’re just going to ignore it”

Re: How often do full-body MRIs find cancer?

#143
post #135

Arguments against proactive MRI scanning always seem to have a whiff of status quo bias to them. Yes, right now MRIs are expensive and false positives are common, but if regular scans were widespread, it's likely this result in innovations that would drive down costs, improve accuracy, as well as producing a much larger corpus of data with which to guide diagnosis and reduce false positives. To use a software analogy…

There's a softer component to healthcare which is that people can overreact to medical results. If a doctor administers a scan, finds a handful of likely benign things but wants to administer another scan later on down the line, I'm probably much more likely to look for a second opinion that tells me to cut them out (even if it may not be medically necessary) than trust my doctor that "it's probably fine". It's proba…

But surely this would decrease as we learned more from more frequent MRI scanning. Doctors and patients would be less likely to overreact, and we'd settle in on something better?

I'm not an expert though.

Re: How often do full-body MRIs find cancer?

#144
post #136

Arguments against proactive MRI scanning always seem to have a whiff of status quo bias to them. Yes, right now MRIs are expensive and false positives are common, but if regular scans were widespread, it's likely this result in innovations that would drive down costs, improve accuracy, as well as producing a much larger corpus of data with which to guide diagnosis and reduce false positives. To use a software analogy…

False positives trigger more diagnostics some of which can be harmful, not just psychologically but physiologically as well. If false positives are ok, why not build a down time detector that rolls a die every 5 mins and alert on hitting a 6.

Harmful to shareholder value.

Personally I’d rather have cancer checked out rather than have a “wait and die” approach

Re: How often do full-body MRIs find cancer?

#145

Doctors here are cognitively captured by a system designed to limit cost (and that's mostly a good thing) But scanning frequently is overwhelmingly good for the patient. The problem is the doctors. Imagine two possibilities. 1. You scan every six months and a doctor reviews your scans but never tells you anything no matter what 2. You scan every six months and a doctor reviews your scans and only tells you results if…

Why is it good for the patient? I think that to claim this, you'd need to show a difference in outcomes. Here, you have a tool with a ~100% false positive rate, so if we start administering it to everyone, it will almost certainly cost lives. Botched biopsies, unnecessary treatments, other complications. Not to mention the huge cost that would divert money from other welfare programs. So you need to show that when it…

You are deep in the cope here.

There is no world in which biopsies cause more harm than detecting every cancer at stage 1 prevents.

> Not to mention the huge cost that would divert money from shareholders

Ah, that explains it

Re: How often do full-body MRIs find cancer?

#146

Earlier quoted context omitted.

> You're saying it as if detection somehow cures cancer, it doesn't. No, I didn't say the detector would cause cancer to be cured. I said fewer people would die with no downsides. If treatment is sometimes harmful then the detector also fixes that, you'd never treat people without cancer

No, the detector doesn't fix that, that problem is not treating people without cancer. The problem is treating people with cancer that won't kill or harm them during their lifetime. In this case even a low risk treatment becomes harmful, let alone cancer treatments.

So if this is true, it seems that we must accept that many people will die of cancer we could have detected and cured with frequent scans, because doing frequent scans will overall cause more harm to people who didn't need treatment. So the overall death/harm rate would be worst with more frequent scans?

Isn't that then just a problem with the scan and diagnosis? With more frequent scans it seems highly unlikely that we wouldn't improve this process and end up in a better place.

Re: How often do full-body MRIs find cancer?

#147

Arguments against proactive MRI scanning always seem to have a whiff of status quo bias to them. Yes, right now MRIs are expensive and false positives are common, but if regular scans were widespread, it's likely this result in innovations that would drive down costs, improve accuracy, as well as producing a much larger corpus of data with which to guide diagnosis and reduce false positives. To use a software analogy…

> Arguments against proactive MRI scanning always seem to have a whiff of status quo bias to them

More and more European countries are currently adopting Lung Cancer screening programs. It's usually limited to people with a certain amount of cigarette-pack-years, but still gives the opportunity for driving more of the innovation you're talking about. I think the main challenge at the moment is that nothing in healthcare is prepared of looking at those scans effectively, a radiologist has full medical education + additional specialization - without effective procedures you'll never be able to provide full-body scans with any meaningful impact.

Re: How often do full-body MRIs find cancer?

#148
post #139
post #136

Earlier quoted context omitted.

False positives trigger more diagnostics some of which can be harmful, not just psychologically but physiologically as well. If false positives are ok, why not build a down time detector that rolls a die every 5 mins and alert on hitting a 6.

Additional diagnostics can also be very expensive. Articles like this don’t seem to understand the overall costs to a health system with decisions like these. And that cost eventually does go down into the pockets of patients one way or another.

I think the point of the conversation is that if we take the predatory capitalism out of the way, using MRIs could potentially be a net benefit overall for everyone.

Re: How often do full-body MRIs find cancer?

#150

“ One study in 2020 found that 95% of asymptomatic patients had some type of "abnormal" finding, but just 1.8% of these findings were indeed cancer.” This has been my experience. And I’ve had oncologists echo exactly this. In the words of one: MRIs find too much. The CT and the PET/CT are the gold standards for finding cancer, finding recurrences, and staging cancer. The trouble is the radiation dose. MRI provides ve…

But saying MRIs "suck at cancer" feels off. They're actually first-line or gold standard for certain cancers
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