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Intravenous Caffeine

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Re: Intravenous Caffeine

#141
post #66

Earlier quoted context omitted.

Not a dentist, but I think it's the acid that causes tooth decay. Microbes create the acid from dissolved sugar in your mouth. The question is whether coffee is acidic enough to do damage even without the sugar.

Hey look something I’m relevant too as a dentist. Tooth decay requires several parameters 1- bacteria 2- bacteria food source 3- acidic environment 4- time We all have the bacteria but the other ones are somewhat controllable. What many people don’t account for is the 4th parameter of contact time. It would be better (for your teeth, not overall health) to rapidly drink several sodas than periodically sip one for sev…

So the trick is to have basic teeth.

Re: Intravenous Caffeine

#142
post #125

Didn’t realise caffeine was used IV in anesthesia. Apparently it speeds up awakening (which makes sense to me as a non-medic). https://theanesthesiaconsultant.com/2019/06/18/intravenous-c... But the story in OP is that the patient received caffeine IV at the beginning of the surgery (inducing severe anxiety). Does anyone know why you would do this?

I know people use a similar strategy for napping. Some people (not me) can fall asleep very fast so they down a coffee and go sleep for a nap...and then wake up super fresh 30 mins later

Combined the effect is stronger than each on its own. Caffeine takes ~15 minutes to work. Sadly no source handy but i once read that naps are most effective below 15 minutes. Above it is possible to enter deeper sleep states and wake up worse than before.

Re: Intravenous Caffeine

#143
> Most people consume ecstasy by mouth, but I’ve heard from many that anal ecstasy is a more satisfying experience.

I don't know why now and why this, but this has convinced me that I really need to cut down on what I read online. 99% of it does not go towards my life objectives and 100% of it is probably taking up space in my brain. To be clear, I would have laughed at that fact and moved on before. It just hit me differently today; I could be thinking about my family, work, friends, whatever, but now I know some irrelevant fact about ingesting drugs via the butt.

Re: Intravenous Caffeine

#144

Earlier quoted context omitted.

> Dunno what would happen if I asked for one outright... Nowadays unless you're over 65 you'd be labelled with "drug seeking behavior" (in your records) and sent home with nothing and a "come to the hospital when you pass your stone." Forget the fact that the difference between drug-seeking behavior and legitimately needing something stronger is indistinguishable, and forget the fact that it will cost thousands upon…

American healthcare is a mess because of religious shit like this.

Huh? The country where you got Oxycotin for a headache only a decade ago doesn’t prescribe pain relief because of religion?

Re: Intravenous Caffeine

#145

Earlier quoted context omitted.

It's not religious - it's an overcorrection based on rampant over prescription of pain killers for years.

It might be both. An over-correction made more likely in part due to religious beliefs.

Go to Europe and you don’t get pain medication unless you’re in the hospital.

Is that due to religiousness too?

Re: Intravenous Caffeine

#146

> Most people consume ecstasy by mouth, but I’ve heard from many that anal ecstasy is a more satisfying experience. I don't know why now and why this, but this has convinced me that I really need to cut down on what I read online. 99% of it does not go towards my life objectives and 100% of it is probably taking up space in my brain. To be clear, I would have laughed at that fact and moved on before. It just hit me d…

I guess I don't understand why people are shocked to learn that recreational drugs can be ingested rectally, but don't bat an eye about the existence of medicinal suppositories. (Or maybe people are shocked to find out about suppositories?)

Re: Intravenous Caffeine

#147
I think this may be referring to this study: https://pubmed.ncbi.nlm.nih.gov/29206091/

"Effects of caffeine administration on sedation and respiratory parameters in patients recovering from anesthesia"

> Caffeine has been shown to enhance the speed of recovery from general anesthesia in murine models, though data in human patients is lacking. This is a retrospective review of intravenous caffeine administration (median dose 150 [125, 250] mg) to 151 heavily sedated patients in the post-anesthesia recovery area, to determine the association between caffeine administration and changes in sedation score, respiratory rate, and oxyhemoglobin saturation.

Re: Intravenous Caffeine

#148
post #142
post #125

Earlier quoted context omitted.

I know people use a similar strategy for napping. Some people (not me) can fall asleep very fast so they down a coffee and go sleep for a nap...and then wake up super fresh 30 mins later

Combined the effect is stronger than each on its own. Caffeine takes ~15 minutes to work. Sadly no source handy but i once read that naps are most effective below 15 minutes. Above it is possible to enter deeper sleep states and wake up worse than before.

So when people talk about napping like this, do they ever actually "fall asleep"? I cannot possibly imagine falling asleep in 15m in the middle of my work day or whatever.

Re: Intravenous Caffeine

#149

> Most people consume ecstasy by mouth, but I’ve heard from many that anal ecstasy is a more satisfying experience. I don't know why now and why this, but this has convinced me that I really need to cut down on what I read online. 99% of it does not go towards my life objectives and 100% of it is probably taking up space in my brain. To be clear, I would have laughed at that fact and moved on before. It just hit me d…

I guess I don't understand why people are shocked to learn that recreational drugs can be ingested rectally, but don't bat an eye about the existence of medicinal suppositories. (Or maybe people are shocked to find out about suppositories?)

You've missed the point. The GP is saying that consuming data at random does not contribute towards the things they personally prioritize in life.

Re: Intravenous Caffeine

#150

I had heard that there's a community of people who insufflate caffeine on Reddit, but this one is news to me. Seems a little funny to go through all the trouble and extreme stigma of injecting yourself with an IV drug, only to pick ground up coffee beans as your poison of choice (!) The study is interesting mostly for the fact that someone tried it, but ultimately the results don't show a very strong effect. I wouldn…

> all the trouble and extreme stigma of injecting yourself

IM and subQ is surprisingly not much trouble, as long as you have a relatively pure dissolvable compound and safe solvent (various oils or bacteriostatic water) it takes like 2 minutes and $1.50 in supplies (a $0.25 syringe, two $0.25 needles, and a $1 PVDF/PETF 0.22um syringe filter). Not much more hassle than at-home insulin or TRT injections.

But definitely a huge stigma, and often the pharmacokinetics of IM/subQ administration aren't desirable for many drugs.

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