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Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

independent.co.uk

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Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#141

Post by lm28469 »

bcrosby95 wrote: post #131
lm28469 wrote: post #109

Earlier quoted context omitted.

Of course, healthy food taste bad and the only good tasting food is junk food, gotcha It tastes bad compared to junk food the same way caffein is bland compared to cocaine, ie. you have to be addicted and in denial to believe it

Lol. You don't have to be an addict too admit caffeine is bland compared to cocaine. I would say properly cooked, fresh healthy food tastes better than junk food. But most people don't have time for that.

> But most people don't have time for that.

But again, if the best economical system of the galaxy in the richest country of the universe can't guarantee basic things such as feeding yourself properly I'd say you have quite a big problem

When do we start acting ? 50% obesity ? 75% ? It's already the top 1 cause of death (cardiovascular disease). What does it say about our society ? Looking at it from the outside makes it look like sabotage if not suicide, very few people profit from it, and in the long run everybody loses

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#142

Post by NotPavlovsDog »

automatic6131 wrote: post #132
counttheforks wrote: post #90

Earlier quoted context omitted.

Like taking the drug? If you're implying people should "just eat less", that's clearly not very reliable.

[flagged]

If you're paying for insurance in the US you are paying for them. Check out how insurance pools work. Society, even a wild capitalist society, benefits from healthier members.

I'm a former professional athlete and am currently, in my middle age, in better shape than most, including youths in their 20s, with blood tests to prove it.

When I was making weight, it was extremely difficult to find the balance to fine-tune the diet. Those 400 grams for me were just as difficult to shed, while performing to task. And I had a professional team behind me.

Consumerist civilization is obsessed with the magic pill, we agree on that. A pharma subscription for life is not the solution. However, I personally know, and there are people like that commenting in this post, individuals that were unlucky to be born obese. If you are going to take a grand statement position, familiarize yourself with what that does to a hormonal system. And that is only one sub-case of many where obesity is completely outside of an individual's control.

With industrialized food, including sugar, HFC and carbohydrate lobbying corrupting the policy in the US for longer than 70 years, and that is a number simply of convenience, since we have easily accessible records of such industry lobbying, obese individuals are not the cause of the problem.

Having more tools to address obesity is a good thing. Hopefully, one arrow of many towards a systemic approach.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#143

Post by fourseventy »

ralmidani wrote: post #69
fourseventy wrote: post #39

Pro tip, you can lose weight for free with no drugs at all.

I agree with you regarding the general population. I also hope we can agree that not everyone attains meaningful weight loss with just diet and exercise. The human body is incredibly complex, with a spectrum of natural compositions, metabolisms, etc. Your post dismissing these nuances risks being interpreted as “thin privilege” (my wife is a Dietitian and taught me the concept). For what it’s worth, I’m against treat…

I can't take anyone seriously who uses the phrase "thin privilege".

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#144

Post by fourseventy »

bluedevilzn wrote: post #87
fourseventy wrote: post #39

Pro tip, you can lose weight for free with no drugs at all.

This is equivalent to saying, you don’t need a cure for AIDS. You can just avoid getting it by not having any sex. This is easier for some people but not a solution for the general population. Similarly, eating less is easier for some people while others are genetically or psychologically predisposed to eating more than they need.

No it's not. You can avoid getting fat by not overeating, but if you do end up getting fat you can cure it with diet and exercise. You can't cure AIDS.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#145

Post by fourseventy »

pwinnski wrote: post #126
fourseventy wrote: post #39

Pro tip, you can lose weight for free with no drugs at all.

Pro tip, you (some percentage of you) can (for some definition of can) lose weight for free (your mileage may vary) with no drugs at all. The fact that these drugs exist and work demonstrates the hormonal link that decades of research has shown is there. Also, the prices of healthy food is much higher than the prices of unhealthy food thanks to subsidies and scale. But that's secondary to the fact that many people ac…

I promise you that every human can lose weight for free. People absolutely can "just eat less" they just choose not to.

Let me give you an example of something that humans really can't do. "Humans can't breathe unassisted underwater". See the difference?

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#146

Post by Retric »

lm28469 wrote: post #140
Retric wrote: post #130

Earlier quoted context omitted.

Again, most people who gained weight were adults. Someone who was 18 in 1975 is only 66 today. Young kids are more likely to be obese but it’s only 22.2% for 12 - 19 year olds vs 44.3% among adults aged 40 to 59.

Kids burn much more calories than adults, once their metabolism starts slowing down they'll take the hit "only" is quite an understatement, having a quarter of your youth being physically disabled is quite alarming

I agree ”only” isn’t the best descriptor. Still it’s clear it isn’t simply people eating a constant amount rather calorie consumption is significantly increasing with age.

Weight gain doesn’t seem to be a metabolic issue, rather on average people eat just a little more and gain just a little more weight every single year and metrics like obesity and morbid obesity smooth over this underlying trend as even the morbidly obese still tend to gain weight.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#147

Post by pwinnski »

fourseventy wrote: post #145
pwinnski wrote: post #126

Earlier quoted context omitted.

Pro tip, you (some percentage of you) can (for some definition of can) lose weight for free (your mileage may vary) with no drugs at all. The fact that these drugs exist and work demonstrates the hormonal link that decades of research has shown is there. Also, the prices of healthy food is much higher than the prices of unhealthy food thanks to subsidies and scale. But that's secondary to the fact that many people ac…

I promise you that every human can lose weight for free. People absolutely can "just eat less" they just choose not to. Let me give you an example of something that humans really can't do. "Humans can't breathe unassisted underwater". See the difference?

I hope that your ignorance and attitude here is somehow restrained as you encounter people in life, and that you never find yourself facing any sort of medical issue or on any medicine that puts you behind a lifelong eight-ball.

You could read about catabolism and metabolic suppression, or lupus, or lipedema, or just carry on, but please, don't be mean to people in real life.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#148

Post by drewbug01 »

hungryforcodes wrote: post #89
drewbug01 wrote: post #23

Earlier quoted context omitted.

> Eat too much and you get sick (seriously like 2 bites and you're done eating). While I’ve know some people experience more severe GI issues or nausea with the drug, this is quite the exaggeration. A drug that made it difficult or impossible to actually consume enough food to survive (more than “two bites”) would be wildly unsafe to prescribe.

Not at all short term. This is EXACTLY what fasting is. In fact a pill you could take in the morning that would suppress your appetite for 24 hours would be fantastic. You could use it three days a week with no ill effects and loose weight.

True.

The comment I was replying to was talking about Mounjaro, which is a weekly injectable - and thus no way to do it for only three days a week. In that context, if Mounjaro made it impossible to eat to the degree the commenter described, it would be wildly unsafe (because of how long each shot lasts).

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#149

Post by drewbug01 »

msrenee wrote: post #64
HDThoreaun wrote: post #37

https://astralcodexten.substack.com/p/semaglutidonomics These new weight loss medications are the solution to obesity. Imo this is one of the biggest medical advances of the century and at least in urban areas of wealthy countries, I don’t think we’ll see obese people anymore in 10 years. The pharma companies realized they’ve got something truly revolutionary so they took the old tried and true drug dealer strategy.…

Are they the solution to obesity? I'm curious as to whether the weight stays off long term. 10 or more years at least or else it's just another bandaid. What we need is better access to nutritious food that doesn't take up so much of folk's scant downtime and tight income. I understand there's lots of reasons people are obese that aren't just laziness, but the drug doesn't solve those either. They're still not gettin…

> 10 or more years at least or else it's just another bandaid.

I wonder what the long-term health outcomes would be between two groups: one group that was obese the whole time, and another group whose obesity was delayed by ten years.

I suspect the latter group would end up having fewer negative health outcomes over the course of their life - 10 years of essentially “reduced wear and tear” on different systems in their bodies. That is to say - even if it’s a bandaid, it may still be really useful for public health.

Re: Diabetes drug Mounjaro was available at $25/month, then increased to $1k/month

#150

Post by refurb »

HDThoreaun wrote: post #37

https://astralcodexten.substack.com/p/semaglutidonomics These new weight loss medications are the solution to obesity. Imo this is one of the biggest medical advances of the century and at least in urban areas of wealthy countries, I don’t think we’ll see obese people anymore in 10 years. The pharma companies realized they’ve got something truly revolutionary so they took the old tried and true drug dealer strategy.…

They never “got em hooked for cheap” because “the cheap price” was for diabetes not obesity.

Pharma companies arent allowed to have copay programs for off label use.

Promoting off-label use is why Pfizer was fined $3B. Its illegal.

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