The issues themselves aren't punching down, but the way he's using the characters is. Imagine Alice deciding to falsely accuse the PHB of sexual harassment to get rid of him. Or Asok becoming a manager and only promoting members of his caste. I feel like this is like that.
I transitioned at work, and I've tried really hard not to be this character. I asked people to use my new name and pronouns but never complained to HR if they didn't. I made an effort to be as friendly and hardworking as possible, so that my conservative coworkers wouldn't see me through the lens of the "culture wars" like this that they're fed. This kind of comic was the stereotype I faced.
It worked for me. I changed peoples' minds, got respect for being reliable no matter my looks, and eventually started passing so nobody remembers I'm trans anymore.