For a year I had my home office setup with LED strip lights all the way around the room. They were mounted on a narrow shelf encircling three walls. Color temp was about 6000K. I loved it, for a while. It felt like a fresh bright day. However, after some months of 12 hours a day of working in this environment, I started having pain in my eyes, almost as if they were being squeezed. This discomfort persisted for a mon…
Apart from that, having a screen that is too bright can certainly cause problems. Especially if the contrast is very stark to the surrounding environment.
I personally use a light theme when it's very bright outside/inside and a dark theme when it's dark + my monitor brightness at home is set to ~70% which is plenty.