I feel like the #1 downside of Python for the last few years is that you cannot take advantage of multiple cores of a CPU easily. Especially when you think it is heavily used in data analysis. We use Python for data analysis as well, and for 95% of operations we are doing, numpy is fast enough that we don't have any complaints. But sometimes, we do wish to be able to take advantage of all the cores in our CPUs, espec…
Distribute your data and run everything as dask.delayed and then compute only at the end.
Also check out legate.numpy from Nvidia which promises to be a drop in numpy replacement that will use all your CPU cores without any tweaks on your part.