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Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

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Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#141

Post by wirrbel »

dhimes wrote: post #90
ypcx wrote: post #76

Earlier quoted context omitted.

In my personal case I'm not really able to enter and maintain good ketosis levels without also fasting intermittently. Intermittent fasting is key to enabling me to lower my caloric input because of the momentum of the fasting phase carried over into the eating phase, e.g. smaller stomach and more effective metabolism. I currently fast about 12 hours per day (including the sleep phase), which doesn't sound like much…

As an N of one, I present my situation: Since mid-January this year I have been fasting intemittently. I have zero calories before 5PM, and I am usually in bed by 10. I exercise most weeks between 4 and six days, but only two or so are "vigorous" for me. My workouts are mid-day. When I eat, I eat normally for me, which is lower carb and higher protein, but not (knowingly) keto or anything. I have lost about 10 pounds…

when was your last test before the one you had?

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#142

Post by rconti »

throwaway_tech wrote: post #17

The title is terrible, it should read ketosis/ketones may prevent, reverse age-related effects within the brain. "Low carb" as the title currently reads does not necessarily result in ketosis and your body/brain running on ketones, which appears to be the scope of this study. There is more to dietary ketosis than low carb, just as an example carnivore or paleo diets are low carb, but those will generally not result i…

Anything that requires me to radically change my diet to experiment with myself "just to see", that takes a minimum of 2-3 months, is a hard pass. It's just not that interesting to most of us for a vaguely hand-wavey possibly useful experiment.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#143

Post by lanternslight »

cageface wrote: post #134
wirrbel wrote: post #111

Earlier quoted context omitted.

Meat also raises insulin, much less than carbs, but on a carnivore diet I can imagine this to happen. The keto diet with ratios has been designed as a diet for epileptics, so in a ratio that maintains both body weight in a healthy range and induces ketosis and avoids ceizures (note: 1920s medicine or something). So the high fat content kind of is there to actually give you the energy so that you don't loose weight. O…

Meat raises insulin levels significantly. A steak spikes your insulin harder than a plate of spaghetti.

Study link?

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#144

Post by bad_user »

I have been on Keto for about 8 months, felt terrible and interrupted the diet, only to later find that a lot of the theory behind it (the CIM model) is complete bullshit.

And whenever seeing claims of the effects of low carb or keto diets, most claims are confounded by the diet being hypocaloric, or with a significant variance in protein when compared with control, with its proponents constantly shifting the goal posts.

This study seems interesting and it has been known that ketosis can help epileptics. But take it with a grain of salt ;-)

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#145

Post by wtetzner »

skizm wrote: post #102
throwaway_tech wrote: post #17

The title is terrible, it should read ketosis/ketones may prevent, reverse age-related effects within the brain. "Low carb" as the title currently reads does not necessarily result in ketosis and your body/brain running on ketones, which appears to be the scope of this study. There is more to dietary ketosis than low carb, just as an example carnivore or paleo diets are low carb, but those will generally not result i…

How does working out at a high intensity work when in a state of Ketosis? I lift weights and/or do HIIT 5x per week and occasionally add running on top of that. I've always been weary of going low carb or trying a keto diet because I feel like I just won't have the energy to continue my training regimen at its current intensity. The typical advice is to eat your allocated carbs 1-2 hours prior to your workout, howeve…

I think it really depends on how long you've been in ketosis, and how well adapted you body is to running on fat.

At first you will absolutely have less energy, but it seems like the more fat-adapted you are, the more energy you'll have. At some point it seems like you actually have more energy to work out.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#146

Post by lanternslight »

ravenstine wrote: post #81
1MachineElf wrote: post #63

Earlier quoted context omitted.

Unless one has too much lean meat. The body will convert excess protien into carbs. It's better to stick with fatty cuts only.

This also depends on eating frequency. If someone has a very low eating frequency, like a single meal every 72 hours, even a meal of lean meat may not knock a person out of ketosis, at least for very long. I've fasted that long and eaten a huge meal of lean meat, multiple times, and my keto testing strips always remain dark purple. As much as I think keto and carnivore are lightyears past the average American's diet,…

How many calories are you eating, and what is your fat/protein ratio? A higher fat rate might get you the energy you seem to be lacking.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#147

Post by cageface »

eatmyshorts wrote: post #73
uptownfunk wrote: post #25

IF has really saved my life. I definitely feel like i reverse aged a few years as a result of it. I enjoy food more now, weight is in check, I look younger.. hard to beat the benefits.

As it turns out, insulin resistance, like that associated with type-2 diabetes, is also related to inflammation (apparently due to cytokines: https://www.webmd.com/diabetes/inflammation-and-diabetes ), which in turn is correlated with heart disease. As I understand it (disclaimer: I'm not a doctor), the inflammation results in damage to the blood vessels, which your body repairs by using cholesterol, among other thin…

Dietary cholesterol is very directly correlated with blood cholesterol levels. You can feed someone cholesterol and directly watch their levels spike. But your body will clear it if you give it time which is why your fasting cholesterol may not show this if you have naturally low levels.

But during that window if time that cholesterol is active in your blood it's not doing you any favors. This is why heart attacks very often follow shortly after a meal.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#148

Post by hoka-one-one »

Is it too much to ask that anyone promoting low-carb based on personal experience post bloodwork? I think it's pretty clear no one on here is well-versed in nutrition as we're all programmers, so maybe it'd be good to have some intellectual integrity.

I'm interested in prolactin, thyroid, liver, cholesterol, CO2.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#149

Post by bad_user »

throwaway_tech wrote: post #17

The title is terrible, it should read ketosis/ketones may prevent, reverse age-related effects within the brain. "Low carb" as the title currently reads does not necessarily result in ketosis and your body/brain running on ketones, which appears to be the scope of this study. There is more to dietary ketosis than low carb, just as an example carnivore or paleo diets are low carb, but those will generally not result i…

> If you have never entered ketosis and experienced your brain running on ketones, I would suggest you experiment for yourself. I would say a minimum 2-3 months which should be enough time for your microbiome to change and your body/brain to adapt primarily running on ketones.

I've been on Keto for about 8 months (before giving up), measuring my blood ketones and being in deep ketosis between meals (over 2 mmol/L). I've also seen values going over 4 mmol/L.

In spite of popular belief, nothing happens, there's no magic at the end of that rainbow for most people. If you felt anything different, there's a high likelihood it was just self suggestion, aka placebo.

Also most people are in ketosis before eating breakfast in the morning, because the liver's glycogen is partially depleted overnight, enough for the liver to produce significant ketones. And nothing will make you enter ketosis faster like skipping a meal or two (aka starvation ketosis). People with a healthy metabolism cycle in and out of ketosis all the time.

Also the idea that your microbiome has to change and your body/brain to adapt for you to feel any better and that it takes months ... is a complete myth. Your body takes only mere days to adjust to any dietary strategy. Also the dreaded keto flu is just dehydration from all the lost glycogen, which pulls a lot of water on its way out.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#150

Post by wtetzner »

hanniabu wrote: post #112
ypcx wrote: post #76

Earlier quoted context omitted.

In my personal case I'm not really able to enter and maintain good ketosis levels without also fasting intermittently. Intermittent fasting is key to enabling me to lower my caloric input because of the momentum of the fasting phase carried over into the eating phase, e.g. smaller stomach and more effective metabolism. I currently fast about 12 hours per day (including the sleep phase), which doesn't sound like much…

> In my personal case I'm not really able to enter and maintain good ketosis levels How do you know if you've entered ketosis or what the levels are?

Not the OP, but I've been using this to test my blood for ketones: https://www.amazon.com/gp/product/B0789G8KTG/
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