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Scientists engineer mice genomes to lengthen their lifespans by 30 percent

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Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#141
post #138
post #107

Earlier quoted context omitted.

Strategies for Engineered Negligible Senescence https://en.wikipedia.org/wiki/Strategies_for_Engineered_Negl... gible_Senescence

retry : Strategies_for_Engineered_Negligible_Senescence, here : https://en.wikipedia.org/wiki/Strategies_for_Engineered_Negl...

Cheers! Copy/paste fail. I'm usually good about testing, but obviously not this time.

Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#142

The consequences of longer lifespan to social order are unimaginable. Even increase by dozen of years may result in wars and chaos, especially if the treatment will not be available to everyone. From where I stand it seems that relatively little resources are spent on the research of consequences of longer lifespan compared with the discussions we have about friendly/enemy AI, machines replacing jobs, universal incom…

Don't worry, the treatment won't be available to all, unless it's a cheap pill with no IP constraints on it. Imagine the profits for the producers of a life extending miracle drug.

It would be more like spice on Dune. Hmm... if I recall correctly, the fremens (who had unlimited access to it) were a bloody waring bunch.

Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#143

Earlier quoted context omitted.

I echo this. We're already over-populated on this planet as it is. Yes there's still a lot of available land, but there are reasons we're not using it either to live on, or to farm - too hostile, too wet, too hot/cold, and the cost of terrafirming those areas is prohibitive. Unless we manage to escape this rock, and find a nice Earth 2.0 out there, extending lifespans is pointless. It's driven by pure selfishness, an…

Escaping this rock is no relief either. What happens when there's a Muskovite Empire on Mars and all the rich people move there to let the poor die on an old planet stripped of resources to make that possible? Transfers of wealth like that are already happening - let's not make it interplanetary. Humanity has changed so much in the last few generations and we are still catching up. Maybe we don't understand the conse…

You mean the poor going to mars to work there, rich people will stay at earth ( sounds like the expanse )

Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#144
post #125

Earlier quoted context omitted.

But that is really hard to understand for a non-specialist. Means nothing at all for me.

Well, I'm quite sorry to hear that, but the paper was written for specialists, and its results are primarily interpretable by and relevant to specialists. Why exactly it made it into a press release and news articles is completely inexplicable when analyzed within the bounds of the work.

A popular science, or even general news type reviews of current research are very valuable. However, in the unavoidable simplifications, they do need to keep the main findings correct, not expand into outlandish claims for clickbait

Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#145

Every life extension discussion derails into debates about foreverness; and therein lies the problem: humans of all backgrounds (even today) are dropping dead of health problems at 60 years of age. Thus, foreverness is science-fiction with our current understanding. Baby-steps first perhaps? Regardless, many agree foreverness is not possible - and if it was - I would not want it.

It's a red herring anyway. The valid question is, would you prefer to remain alive today? You're free to answer in the negative at any time, but it would be nice not to have the decision taken from you by mere biochemistry.

Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#146

The consequences of longer lifespan to social order are unimaginable. Even increase by dozen of years may result in wars and chaos, especially if the treatment will not be available to everyone. From where I stand it seems that relatively little resources are spent on the research of consequences of longer lifespan compared with the discussions we have about friendly/enemy AI, machines replacing jobs, universal incom…

My main fear around longevity treatments is that a panicked, conservative reaction will condemn me to an unnecessary death while arguments rage and people moralise endlessly.

Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#147
post #140

The consequences of longer lifespan to social order are unimaginable. Even increase by dozen of years may result in wars and chaos, especially if the treatment will not be available to everyone. From where I stand it seems that relatively little resources are spent on the research of consequences of longer lifespan compared with the discussions we have about friendly/enemy AI, machines replacing jobs, universal incom…

> Even increase by dozen of years may result in wars and chaos Care to explain? I don't see why humans living on average a dozen years longer would inevitably lead to "wars and chaos" and a breakdown of social order. Indeed, we saw lifespans increase by two dozen in the last 80 or so years and nothing happened at all. The usual arguments about overpopulation don't seem to apply to developed countries; if anything it'…

I can think of a few pertinent cases. With every new generation you get fresh perspectives. Old practices die because generations die with them. Can you imagine slavery practices getting a "lifespan increase."

I bet the "cold war" mind set works the same way. You rarely see cold war brought up by much younger folks. It's always an old gen rehash.

What about a ruthless dictator like Kim Jong Un getting 12 extra years on earth?

Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#148

Summary of pro death arguments re: longevity progress Fairness Only rich people will get it. (no tech has ever done this.) Better to give money to the poor than science. (family,city,state,nation, has proven local investment beats foreign.) Bad for society Dead people make more room for new, other people. (consider going first.) Run out of resources (live people discover/extract/renew better than dead or nonexistant)…

How about: bad ideas get to remain in power for much longer, because the generations of administrators/voters/executives that enforce them don't turn over. Death ensures adaptation. For example, climate change denying oil barons have done much damage to the world, but we can take some comfort in the knowledge that they will soon die (or at least retire) and that their successors will probably be a little more enlight…

An encouraging counter-argument is to watch the way that age cohorts have changed their attitudes to gay marriage in successive surveys. Society as a whole has become a lot more supportive, very fast, and all ages have been changing their attitudes. It's not just that young supportive people are aging upward into older cohorts, but also that old people who had negative attitudes have been softening their opposition, and many have crossed over from opposition to support.

The idea that the old have fixed bad ideas is mistaken. All ages of people can be persuaded.

Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#149
post #140

The consequences of longer lifespan to social order are unimaginable. Even increase by dozen of years may result in wars and chaos, especially if the treatment will not be available to everyone. From where I stand it seems that relatively little resources are spent on the research of consequences of longer lifespan compared with the discussions we have about friendly/enemy AI, machines replacing jobs, universal incom…

> Even increase by dozen of years may result in wars and chaos Care to explain? I don't see why humans living on average a dozen years longer would inevitably lead to "wars and chaos" and a breakdown of social order. Indeed, we saw lifespans increase by two dozen in the last 80 or so years and nothing happened at all. The usual arguments about overpopulation don't seem to apply to developed countries; if anything it'…

It's worth noting that people getting much older (what the OP is saying) and the increase in life expectancy in the last century (what you mentioned) is quite different as the increase of life expectancy is due to a drastic decrease in child mortality not longer life for those who made it to adulthood. Once you make it to 20 or so, chances are you'll stick around for another 50-60 years even a century ago.

Re: Scientists engineer mice genomes to lengthen their lifespans by 30 percent

#150
post #147
post #140

Earlier quoted context omitted.

> Even increase by dozen of years may result in wars and chaos Care to explain? I don't see why humans living on average a dozen years longer would inevitably lead to "wars and chaos" and a breakdown of social order. Indeed, we saw lifespans increase by two dozen in the last 80 or so years and nothing happened at all. The usual arguments about overpopulation don't seem to apply to developed countries; if anything it'…

I can think of a few pertinent cases. With every new generation you get fresh perspectives. Old practices die because generations die with them. Can you imagine slavery practices getting a "lifespan increase." I bet the "cold war" mind set works the same way. You rarely see cold war brought up by much younger folks. It's always an old gen rehash. What about a ruthless dictator like Kim Jong Un getting 12 extra years…

All these dictators in Africa ruling for (eternal) life ?!! What a nightmare !
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