Chemical clears Alzheimer's protein and restores memory in mice • Hacker News Board

Re: Chemical clears Alzheimer's protein and restores memory in mice

#141

Post by bootload » Fri, Dec 18, 2015, 1:04 AM UTC

CWuestefeld wrote: post #129

CamperBob2 wrote: post #125

Earlier quoted context omitted.

When you realize that pretty much every disease and condition has similar papers written about it, you start to realize that the way we do medical research is pretty messed up. Keep in mind that they still haven't really decided whether salt is bad for you or not, or what the real effects of dietary cholesterol are. Widespread conditions that should be much easier to research and understand than Alzheimer's are still…

you start to realize that the way we do medical research is pretty messed up. The way the media reports on research (not just medical) is really messed up.

"The way the media reports on research (not just medical) is really messed up."

Might have something to do with wanting simple answers. I notice this happening on HN.

If I add a new post where it's a general science article I post both the general article and the original academic paper. HN readers choose the general over the technical article most times except when it comes to HN technical areas of interest. The level of reader understanding may influence article choice.

Re: Chemical clears Alzheimer's protein and restores memory in mice

#142

Post by blisterpeanuts » Fri, Dec 18, 2015, 2:59 AM UTC

celticninja wrote: post #132

blisterpeanuts wrote: post #126

Earlier quoted context omitted.

What's the ratio of U.S. scientists to Korean scientists? 10:1 or so? I would expect to see 10x as many fraud cases in the U.S. But there have been some doozies in Korean science, especially the stem cell guy who really embarrassed and shamed his country with the extent of deception he practiced. Brilliant, but also crazy.

where is that ratio pulled from? your ass? My point is that it was a generalization against korean scientists and a few instances is not representative of an entire group. Your point seems to be that the korean instances are somehow higher profile, but if that was the case then UK research science would be the worst because the vaccine/autism scandal has probably had the most far reaching after effects and infamy.

Approximately 10x as many scientific documents produced in the U.S. as in S. Korea.[1]

Ratio of U.S. to ROK scientists is about 6:1.[2]

OK, so # of scientists isn't 10:1. But in terms of scientific activity, the U.S. is far and away more productive.

1. http://www.scimagojr.com/countryrank.php 2. http://chartsbin.com/view/1124

Re: Chemical clears Alzheimer's protein and restores memory in mice

#143

Post by celticninja » Fri, Dec 18, 2015, 8:20 AM UTC

blisterpeanuts wrote: post #142

celticninja wrote: post #132

Earlier quoted context omitted.

where is that ratio pulled from? your ass? My point is that it was a generalization against korean scientists and a few instances is not representative of an entire group. Your point seems to be that the korean instances are somehow higher profile, but if that was the case then UK research science would be the worst because the vaccine/autism scandal has probably had the most far reaching after effects and infamy.

Approximately 10x as many scientific documents produced in the U.S. as in S. Korea.[1] Ratio of U.S. to ROK scientists is about 6:1.[2] OK, so # of scientists isn't 10:1. But in terms of scientific activity, the U.S. is far and away more productive. 1. http://www.scimagojr.com/countryrank.php 2. http://chartsbin.com/view/1124

And I would still call it an unfair generalisation.

It's almost as if you are saying that some fraud is to be expected and is therefore fine when actually any fraud is wrong.

Re: Chemical clears Alzheimer's protein and restores memory in mice

#144

Post by pcrh » Sun, Dec 20, 2015, 11:57 AM UTC

brwnll wrote: post #91

keeptrying wrote: post #68

There have been at least 3 previous solutions for AD in mice which have never panned out in humans.

Source?

Actually its more like 300 treatments that haven't panned-out...

‘Too much good news’ – are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer’s disease?

https://www.ncbi.nlm.nih.gov/pubmed/?term=20542579