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The shingles vaccine may reduce the risk of dementia

economist.com

131–140 of 234 posts

Re: The shingles vaccine may reduce the risk of dementia

#131
post #75

Earlier quoted context omitted.

Have you tried asking your PCP?

I'm pretty confident I could talk my PCP into it! I'm just wondering if there is some easier retail way to do it.

If you DM your provider through their health portal it's likely they'll write an order without requiring an office visit.

Re: The shingles vaccine may reduce the risk of dementia

#132
post #92
post #88

Earlier quoted context omitted.

You can just ask for vaccines at the pharmacy. I got a potentially missed childhood vaccination as an adult and they asked a few questions about why I wanted it, but were happy to give it to me. If it’s something odd you might need to go to a travel clinic.

Not this one you can't.

I got mine at a tiny off-chain pharmacy. I just lied about my age. They didn't even check my ID. I did it in my early 30s, definitely did not look 50. Very happy I did so, have seen a few younger friends go through shingles and it _sucks_.

Re: The shingles vaccine may reduce the risk of dementia

#133
post #83

I'm in my 40s with genetic predisposition for Alzheimer's. Been seriously considering the past year or two paying out of pocket for Shingrix. I think it would be ~$500 total for two doses. Sure, I could wait 7 or 8 years until I qualify via insurance, but is that really worth the risk for what is an easily absorbed cost to me? Especially when I have a friend in her late 30s who just went through a very rough bout of…

On the topic of vaccines, if you were vaccinated against measles before it switched to the two-dose schedule (1989 in the US), you might want to have your titers measured. I was vaccinated in the early 70s when it was a single dose. With measles in the news recently, I asked my doc to add a measles antibodies test to my blood draw. Came back negative. No immunity. I went to the local pharmacy and got an MMR booster t…

If you were vaccinated on the normal schedule, what year would you generally be born to be vaccinated with the single dose?

Re: The shingles vaccine may reduce the risk of dementia

#134

Earlier quoted context omitted.

That seems like being penny wise and pound foolish.

Looks like the GP is in the UK. I tried to go private (also not 50), but everyone just refused. Pharmacy, GP, private GP. Currently I'm arranging it in the third country because WTAF. (UK becoming the dirtiest and sickest country of Europe one more time)

Weird, I went to a travel vaccination clinic in London and got it no questions asked (the nurse was even familiar with the dementia research). Try calling privatemedicalclinic.com ?

Re: The shingles vaccine may reduce the risk of dementia

#136
I got shingles in my early 50s and did not know there were antivirals that could help mitigate its effects. I now have postherpetic neuralgia and the pain is not quite enough to off myself but the fact that I have to live with this for the rest of my life weighs me down.

It turns out that "pain management" is more art than science and almost all the pharma options out there come with significant risks and concerns. I ended up turning to kratom to manage the pain, which it does, but it's come at significant cost as well (addiction being one of them). I'm now going to try peptides (ARA-290 and BPC-157) to see if maybe that can help but it's all a crap shoot.

I share this as a warning/advice: get the vaccine if you can, even if insurance resists, push back. It may be worth it out of pocket IMHO. If you can't, remember to get access to antivirals immediately if you can.

Re: The shingles vaccine may reduce the risk of dementia

#137

Unfortunately this is a spurious finding. See this presentation: https://youtu.be/qlTnnQytOJ0 The mechanism is that people with the shingles vaccine are less likely to visit the hospital (because they don't get shingles). Because they have fewer hospital visits they are less likely to receive an incidental diagnosis of dementia from a hospital.

There's also this whole thing: https://xkcd.com/882/

There's countless treatments and countless diseases. It is very much worth combing data to find treatments with potential off-label uses, but with that many combinations of treatments and diseases, much more care needs to go into eliminating not just non-causative correlations, but straight-up random correlations that have a very small probability of happening on their own, but are likely to happen in a large enough group of comparisons.

Re: The shingles vaccine may reduce the risk of dementia

#138

I got shingles in my early 50s and did not know there were antivirals that could help mitigate its effects. I now have postherpetic neuralgia and the pain is not quite enough to off myself but the fact that I have to live with this for the rest of my life weighs me down. It turns out that "pain management" is more art than science and almost all the pharma options out there come with significant risks and concerns. I…

The antiviral treatments for shingles are not very practical in that by the time you decide to visit the doctor it may already be too late for them to work.

Re: The shingles vaccine may reduce the risk of dementia

#139
post #18

Earlier quoted context omitted.

I read before that iirc because of waning protection it’s better not to get it too early. It’s not clear to me why you can’t get it twice, but what I read (and it was some online discussion so could be wrong) was that someone had been specifically told by their doctor to wait to 50 as the best spot to get it. I’d like to know more, I’m in my 40s and would be happy to get it now too but not if it was going to be worse…

But surely you can do a booster shot?

I've had two shingles shots: Zostavax and Shingrix. There's no reason you couldn't take either shot again. You might have to pay but no big deal.

I know people who've had shingles and it is not only a major PITA but can be life-threatening, can blind you, etc., just bad stuff. Don't delay taking advised precautions, including injections.

Re: The shingles vaccine may reduce the risk of dementia

#140
post #92

Earlier quoted context omitted.

Not this one you can't.

I got mine at a tiny off-chain pharmacy. I just lied about my age. They didn't even check my ID. I did it in my early 30s, definitely did not look 50. Very happy I did so, have seen a few younger friends go through shingles and it _sucks_.

Sorry Tom, but you definitely look older than your age!8-))
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