Thanks for posting this. Happy to answer questions!
[flagged]
Founder of GitLab battles cancer by founding companies
131–140 of 285 posts
Re: Founder of GitLab battles cancer by founding companies
#132I think you’d find Dr. Richard Scolyer’s story really relatable. He’s an Australian cancer expert who, along with his colleague, is using himself as "patient zero" for a world-first treatment for his own brain cancer. They’re basically doing the research and the treatment in parallel to find a new way forward: https://www.abc.net.au/news/2025-10-30/dr-richard-scolyer-sp...
Re: Founder of GitLab battles cancer by founding companies
#133Earlier quoted context omitted.
Thanks for the inspiration! Is there anything new you've learned about fibrosis in your journey?
I'm not knowledgable able fibrosis except that my tumor expresses a lot of FAP and it is a workable target for radio and immune drugs.
I have sent you an email - any help you can provide in this area.
Re: Founder of GitLab battles cancer by founding companies
#134Thanks for posting this. Happy to answer questions!
Have you just "ordered the cancer vaccine" or this is not yet that easy?
Re: Founder of GitLab battles cancer by founding companies
#135Earlier quoted context omitted.
Thanks for the warning, I hope that it wasn't a personal experience for you. Thanks for the compliment about the elaborate design. I think that when you make something for one or a few patients it is easier to be more elaborate, even with the same knowledge and equipment. Maybe the TCR and BCR-seq was most helpful for mRNA design and effectiveness monitoring, but hopefully someone else on my team will answer that bet…
The TCR sequencing has been helpful for downselecting TCRs for a TCR based cell therapy, and for monitoring response to various immune therapies (including the vaccines)
Interesting, thanks for your replies.
You should consider publishing a patient case report somewhere, as I believe there are lots of valuable conclusions to be extracted from your work.
Re: Founder of GitLab battles cancer by founding companies
#136Love seeing Sid posting about this and taking the initiative he has. I wish I'd had the resources and time (and abilities of Sid) when my Dad got ALS considering the relatively poor state of ALS treatments.
Re: Founder of GitLab battles cancer by founding companies
#137This story and the guy curing his dogs cancer leads me to believe what's missing is a jurisdiction that allows people with money to do whatever experiments they want/need to move medicine forward.
Do you really expect people to let you possibly kill people with medical experiments without even having to file some paperwork?
Countries are already trying to attract clinical trials, and that includes streamlining approvals.
Re: Founder of GitLab battles cancer by founding companies
#138Earlier quoted context omitted.
You are right on the mark. What triggered me was the slide in Sid's presentation: "Assessing Fibroblast Content of Tumor". Peyronie's is all about Fibroblasts. I actually typed my reply quite a few times, deleting mention of Peyronies and retyping it. It's a shameful condition for me, and I realize that I have to get over this. Peyronie's affects 1% to 20% of men, primarily because it's (if you're anything like me) -…
It’s not quite the same, but I had a frenulectomy done due to severe phimosis leading to pain and bleeding. It was absolutely horrible, and I was shocked at how hush hush we all treat conditions like this. Thankfully there’s a straightforward surgical treatment for it, and I hope that you’re successful on your quest around Peyronie’s!
This reminded me of my own story, when I was 15 and had phimosis. I was embarrassed to talk about it with anyone, so in my desperation I posted about it on a forum that claimed to help kids in need of help. Someone responded and gave me instructions that they claimed had a high success rate at treating the condition.
I followed the instructions for a few months and it fixed it. I went back and sent the biggest thanks to the responder. I did not expect to get any help from a random forum.
There has to be swathes of kids struggling with "embarrassing" (in quotes, because they actually aren't embarrassing at all) issues like this. I hope today's internet can provide help to the ones that have nobody to discuss them with.
Re: Founder of GitLab battles cancer by founding companies
#139Took me a while to parse the title
Re: Founder of GitLab battles cancer by founding companies
#140This story and the guy curing his dogs cancer leads me to believe what's missing is a jurisdiction that allows people with money to do whatever experiments they want/need to move medicine forward.
I have met people who credibly are able to do some of this at Prospero. The downside to this siting is that the local government are not super reliable but it’s possible.