Enhancing gut-brain communication reversed cognitive decline in aging mice

Post by meindnoch » Fri, Mar 13, 2026, 9:55 AM UTC

adaptbrian wrote: post #99

systemsweird wrote: post #88

Earlier quoted context omitted.

I think mainstream is mostly looking at the microbiome stuff wrong. Your microbiome is the downstream proxy of good lifestyle habits, not generally something to directly manage. Good diet, exercise, reducing stress, and sleeping well will improve digestion and all the downstream variables like microbiome, physical health, and mental health. This is basic ecology, the bacterial population dynamics in your colon are a…

It certainly anecdotal, but feels like you can positively effect your gut microbiome for example by riding a horse. Ive read research about how other mammals can share their microbiomes with humans, if its not the horses biome then what is it that so satisfingly calming post ride. Would love to be enlightened. Ride a horse if you need to destress, amazing creatures.

Post by papyrus9244 » Fri, Mar 13, 2026, 10:02 AM UTC

m463 wrote: post #103

unrelated but maybe interesting... I had a colonoscopy and had to empty my system. I had 1/2 gallon of this fluid to drink the night before, and the other 1/2 gallon to drink the day of. At that point my digestive system was empty. I will say with an empty system I felt energized and a lot more clearheaded. I wonder if doing this from time to time is helpful to your system, and furthermore if eating smaller portions…

Post by meindnoch » Fri, Mar 13, 2026, 10:17 AM UTC

theshrike79 wrote: post #44

"You" don't crave stuff, the microbiome in your intestine craves stuff. There are microbes in there that specialize in eating, say, sugar. You don't give them sugar, they send signals to your brain saying "yo, more sugar" This is why if you go on a sugar-free diet (just stop eating candy and sweets) the cravings just go away eventually. The microbes who keep shouting for more sugar either die away or go dormant.

Post by [deleted] » Fri, Mar 13, 2026, 10:47 AM UTC

theshrike79 wrote: post #119

Aurornis wrote: post #72

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If this was true, sugar cravings would disappear when taking antibiotics that kill those microbes. The fact that this doesn’t happen should give you pause about this woo-woo theory of cravings. The reason you crave sugar and fat and other tasty things is that they taste good. You evolved in a world where feeling rewarded and driven to consume more of these was beneficial to survival when food was scarce.

Antibiotics don't kill 100% of the gut biome, if it did so, we'd die. It does some decimation, but not a full genocide.

Post by james-bcn » Fri, Mar 13, 2026, 10:51 AM UTC

throwawaytwit9 wrote: post #59

y-curious wrote: post #30

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What did you do for heartburn? Just looking for ideas. I noticed reducing gluten helped me personally a lot

It may not work for you but I had years of chronic heartburn. While sick with covid in 2020, I stopped consuming coffee and alcohol. It took a few months and for the long covid symptoms to subside, and then no more heartburn. At all. I felt really dumb that I never connected it to coffee before. I didn’t experience direct symptoms from coffee and I didn’t consume an excess amount. But it definitely was the cause.