Live data from Hacker News

Beetroot juice lowers blood pressure by changing oral microbiome: study

news.exeter.ac.uk

131–140 of 165 posts

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#131
post #69

Earlier quoted context omitted.

So? Every living human needs a lot of calories every day.

If you do not differentiate between sugar and calories you clearly can learn a lot about the human digestion and microbiomes. Complex (slow) carbs [does it feed your microbiome predominantly] != easy (fast) carbs [does it quickly go into your bloodstream and cells]

Calorie for calorie beetroot juice has the same sugar content as beets. I am certain you are not asserting that beets are not something that humans would normally digest.

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#132

Beetroot juice is legal “doping”. Of course nothing illegal, only natural, a disadvantage if you don’t utilize it for you. There are beetroot parties at almost any Triathlon event for the runners, apnea divers also get a huge natural and healthy boost. I use it for long runs I don’t really feel the difference every time, but stats and data speak their own language. Give it a try, timing is a bit tricky depending on y…

Should be a raw juice or polish beetroot soup (barszcz) does the job?

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#133

Earlier quoted context omitted.

> Could you provide some evidence to support your assertion that highly enriched foods are degrading health? Getting nutrients from whole foods is generally superior, for absorption and balance and avoiding overdosing, than getting it from supplements, whether taken directly or via enrichment. That said, getting a nutrient any way is better than running a deficiency. For most of agricultural human history, in most so…

> That changed with enrichment. You’re close. According to the paper, that changed with agriculture some 480 generations ago; enrichment is merely the solution.

> that changed with agriculture some 480 generations ago; enrichment is merely the solution

Whoops, typo—I meant nutritionally deficient.

Hunter-gatherers had a varied but volatile diet. Agriculture solved the volatility at the expense of variety. Most agricultural humans across history were nutritionally deficient.

Enrichment (a/k/a fortification) started to solve for the lack of variety, though it’s been historically stymied by our lack of understanding what e.g. vitamins are; modern farming, biology and logistics enable us to actually solve for the problems agriculture introduced to society for the first time.

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#134
post #42
post #7

Earlier quoted context omitted.

Alcohol or just fluoride? I have an aversion to the alcohol washes after reading years ago that the change to your mouth biome may lead to the issues that they are meant to stop.

fluoride with no kind of antibacterial is fine (careful with thymol etc). Check your toothpaste for anti bacterial as well. you want to remove food and plaque, not good bacteria.

But fluoride IS antibacterial.

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#135

Earlier quoted context omitted.

You should definitely use mouthwash. For healthier teeth and problems like Alzheimer might also be correlated: https://expatcircle.com/cms/how-to-clean-your-teeth-and-save...

Erythritol and Xylitol do have a strong correlation with severe coronary diseases and risk of strokes under certain preconditions according to newer studies though. Also not really advisable for people with Irritable Bowel Syndrome.

This is true but how much will your body absorb via a mouthwash?

Erythritol is commonly found in sugar-free or keto-friendly products like beverages, desserts, and snacks. A single serving of an erythritol-sweetened product (e.g., a sugar-free soda, keto ice cream, or protein bar) often contains 10–30 g of erythritol.

Studies, such as the 2023 Nature Medicine study, used a 30 g dose in intervention experiments to simulate typical consumption (e.g., one sweetened beverage or dessert). This dose raised plasma erythritol to 5–7 mM within 30 minutes, a level linked to increased platelet reactivity and clotting risk.

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#136

Back in school I was often told the lead pipes in Roman aqueducts likely played a key role in the fall of Roman. We know lead is a poison with negative long term effects on cognition. The aqueducts were also responsible for Romes ability to proliferate and grow. Lead was both a blessing and a curse. I wonder what future generations will say about our highly enriched and processed diets. Calories have never been cheap…

Could you provide some evidence to support your assertion that highly enriched foods are degrading health? Public health experts contend that enriched foods have improved baseline quality of life. Wheat breads with iron, folate, and B vitamins in the US is an easy example.

If interested in Ultra Processed Foods, of which enriched foods usually are UPF, you can check out a good book called Ultra Processed People. It's not definitive, but it makes a compelling argument that while we don't know why exactly, processed foods containing the same nutrients as their whole brethren have deterious effects on our long term health.

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#137

Earlier quoted context omitted.

If you do not differentiate between sugar and calories you clearly can learn a lot about the human digestion and microbiomes. Complex (slow) carbs [does it feed your microbiome predominantly] != easy (fast) carbs [does it quickly go into your bloodstream and cells]

Calorie for calorie beetroot juice has the same sugar content as beets. I am certain you are not asserting that beets are not something that humans would normally digest.

Well the difference between the veggie and the juice is that the former contains a whole lot more of fiber which is an especially beneficial nutrient for our gut microbiome.

Reading up on juices, I've only heard of experts not being fans of 'em.

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#138

Beetroot juice is legal “doping”. Of course nothing illegal, only natural, a disadvantage if you don’t utilize it for you. There are beetroot parties at almost any Triathlon event for the runners, apnea divers also get a huge natural and healthy boost. I use it for long runs I don’t really feel the difference every time, but stats and data speak their own language. Give it a try, timing is a bit tricky depending on y…

Do we know the mechanism by which this works? Is it just anecdotal, or is this studied at a population/statistical level?

from https://www.outsideonline.com/health/training-performance/be...

  The key ingredient in beet juice, from an endurance perspective, is nitrate. Once you eat it, bacteria in your mouth convert nitrate to nitrite. Then the acidity in your stomach helps convert the nitrite to nitric oxide. Nitric oxide plays a whole bunch of roles in the body. That includes cueing your blood vessels to dilate, or widen, delivering more oxygen to the muscles, faster.

The article summarizes the results of several studies into beetroot juice for physical athletic performance.

  I sent the following summary to Andy Jones, the scientist most associated with beet juice research, to see whether he would agree:

  “It works. It probably works less well in elites, like most things, but there may still be an effect. Higher doses taken for at least a few days in a row probably increase your chances of a positive effect.”

  Jones thought that sounded reasonable. He pointed out that there’s a separate body of evidence emerging that beet juice also enhances muscle strength and power in some circumstances, an effect that Poon’s review confirms.

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#139

If you have trouble in bed, ask yourself if you use Listerine. It kills your mouth’s microbiome and lowers your Nitric Oxide production [0]. [0] https://pubmed.ncbi.nlm.nih.gov/31709856/

I don't use Listerine but I didn't get this: trouble in bed of what kind? I couldn't get it from the linked article. I never knew high blood pressure correlates with bad sleep or bad sex (if anything, meds for high blood pressure come with negative effects on that).

> if anything, meds for high blood pressure come with negative effects on that

It’s really a mixed bag.

Recall that Sildenafil (aka brand name Viagra) was originally developed to treat high blood pressure. Turns out that while it does lower blood pressure, it’s really good for improving erections.

Re: Beetroot juice lowers blood pressure by changing oral microbiome: study

#140

Earlier quoted context omitted.

You should definitely use mouthwash. For healthier teeth and problems like Alzheimer might also be correlated: https://expatcircle.com/cms/how-to-clean-your-teeth-and-save...

Erythritol and Xylitol do have a strong correlation with severe coronary diseases and risk of strokes under certain preconditions according to newer studies though. Also not really advisable for people with Irritable Bowel Syndrome.

What are your sources?

Peter Attia has a blog entry about the weak xylitol-cardiovascular disease research. For Xylitol, see https://peterattiamd.com/xylitol-and-cvd/

  The problem with interpreting these results as a condemnation of xylitol consumption is that diet isn’t the only source of circulating xylitol. This compound is also produced by our own bodies through a process known as the glucuronate pathway, one of the pathways by which we metabolize glucose. So how did the authors ensure they were investigating the relationship between dietary xylitol intake and MACE risk?

  They didn’t. ...
Attia also brings up something the study authours noted:

  The rapid rate of xylitol excretion observed in healthy volunteers with return to near baseline (fasting) levels within hours following ingestion of a significant dietary exposure suggests that the plasma levels observed in our observational (validation) cohort represent variations in endogenous production/levels and not food intake.
Post reply on HN