Low UI density is the new emperor's clothes in modern UI design. It's being actively promoted by companies in order to cut design costs, but the truth is that it's only reasonable on touch interfaces or casual apps.
Mouse interfaces are fundamentally different, because you have much more pointing precision, so it pays off to show more data on the screen. You don't have to cram your interface with with spaces to make it scan-friendly, you just use heterogeneous elements and colors. Look at Blender and you'll know it can be done.
I'm designing a desktop reference manager (https://getcahier.com), and one of its aims is to provide a UI with high information density. The mobile version will be able to adjust the experience, replacing desktop-only interaction patterns with mobile ones, and the UI elements that are shared will be somewhat bigger, so that users are able to interact them with touch.
Apart from that, it seems that the whole industry is confused regarding UI styles. UI frameworks are either favoring touch interfaces and degrading the experience on desktop, or vice-versa. Even Windows 10 released certain parts of the control panel with desktop look and feel and others with touch-friendly but desktop-antagonistic screens. It's time we realize that both platforms are different and we shouldn't degrade one in favor of the other.