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Blueprint health protocol

protocol.bryanjohnson.com

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Re: Blueprint health protocol

#131

Post by meindnoch »

bmikaili wrote: post #124
meindnoch wrote: post #119

Earlier quoted context omitted.

>B12 only occurs naturally in soil LOL. Patently false. B12 is produced by bacteria in herbivores' guts.

Sorry, cobalt only occurs in soil js what I meant. Do you have a comment on the point itself?

Sure, here you go: eating cobalt from the soil wouldn't give you B12, because bacterial fermentation in humans is occurring in the colon, while B12 is absorbed by the ileum.

But actually there's a solution for vegans. As the following paper in Nature eloquently puts it:

"Human faeces contain appreciable quantities of vitamin B12 or vitamin B12-like material presumably produced by bacteria in the colon, but this is unavailable to the non-coprophagic individual."

https://www.nature.com/articles/283781a0

Re: Blueprint health protocol

#132

Post by layer8 »

Shekelphile wrote: post #31
thatguysaguy wrote: post #4

I have no idea whether his stuff will work but I'm glad people are trying wacky stuff to find out.

There is a very weird lack of interest in slowing down or reversing aging in the scientific/medical community in general. To me it seems like it should be a top priority. Life is extremely short and extending our lives shouldn't be a terribly hard feat given there are plenty of biologically immortal and long lived organisms all over our planet.

Treating illnesses, diseases and injuries should have higher priority, as they impact QOL and mortality much more. Once almost everyone gets to age 80 in health, then we can tackle extending the life span.

Re: Blueprint health protocol

#133

Post by layer8 »

neuronic wrote: post #74
RanTig wrote: post #40

I really wish he did his research without being restricted to a vegan diet. He mentioned in one of his videos that his choice for a vegan diet isn't motivated by health, so I can't help but think that part of these recommendations are just there to mitigate the effects of that specific diet. For example, an omnivorous diet might not need certain supplements.

I am glad he is focusing on a vegan diet (especially if no technological revolutions are made in artificially derived animal products). It's nice to learn about the downsides of it in order deal with them rather than just defaulting back to animal products. One of his main points in the intro is not destroying our biosphere and going vegan is the single most impactful thing an individual can do to support that. Suppl…

> not destroying our biosphere

Not sure that having people live longer helps with that.

Re: Blueprint health protocol

#134

Post by loceng »

kkoncevicius wrote: post #34

I love what the guy is doing. It is a one-man experiment that would be very very hard to reproduce, or even get ethics approval and funding for, by a research lab. But on the other hand, I get a sense that the public side of his results are overblown. For example, my field is epigenetics, so I had a look at his "epigenetic clock" results. He uses "DunedinPACE" to track the rate of aging and his result is supposedly 0…

FTA: "I am now accumulating aging damage slower than the average 10 year old"

That to me said to me far more about the average 10 year olds diet and perhaps also likely to an increasing sedentary level.

Re: Blueprint health protocol

#135

Post by meindnoch »

Cthulhu_ wrote: post #108
hgomersall wrote: post #93

Earlier quoted context omitted.

He stays out of the sun? Interesting to learn what the long term consequences of that will be.

It's counterintuitive; people need sunlight to generate vitamin D, but it also causes cancer. People in both the middle-east and the north are often vit-D deficient because of a lack of sunlight exposure, in the north because there not being a lot of sunlight, in the warm/dry climates because they dress and live for the weather which means not a lot of skin is exposed.

People in mediterranian Europe don't dress like that, yet they're nowhere near the top for melanoma incidence: https://www.wcrf.org/cancer-trends/skin-cancer-statistics/

Spain, Portugal, Greece and Italy should be at the top of this list, but they aren't.

Re: Blueprint health protocol

#136

Post by apwell23 »

Shekelphile wrote: post #31
thatguysaguy wrote: post #4

I have no idea whether his stuff will work but I'm glad people are trying wacky stuff to find out.

There is a very weird lack of interest in slowing down or reversing aging in the scientific/medical community in general. To me it seems like it should be a top priority. Life is extremely short and extending our lives shouldn't be a terribly hard feat given there are plenty of biologically immortal and long lived organisms all over our planet.

> There is a very weird lack of interest in slowing down or reversing aging

Uh. We don't even know why we get heartburn and how to treat it. You comment sounds like, why does my toddler lack interest in reading Shakespeare.

Re: Blueprint health protocol

#137

Post by atemerev »

hdarshane wrote: post #122
atemerev wrote: post #44

Earlier quoted context omitted.

My idea of doing this is bringing AGI sooner. Human body is an inelegant and unoptimized vehicle for intelligence.

>Human body is an inelegant and unoptimized vehicle for intelligence. Why do you think so? the impermanence of it? the gradual performance decrease? the biological/physical limitations that constraint it?

Yes, all of this.

Re: Blueprint health protocol

#138

Post by msandford »

Dave3of5 wrote: post #77
mkreis wrote: post #7

Wow, just look at the number of pills he takes every day: https://protocol.bryanjohnson.com/#step-2-supplements And then apparently the same dish, every day... definitely a very scientific approach.

Yeah I noticed this and was going to mention it. That many supplements is very very odd. Many people have lived very long over the years without resorting to that many pills.

The "food" in America has never been grown with more fertilizer. It's probably missing all kinds of stuff that would be there otherwise.

You can buy and eat only organic and that might help. Even that's no guarantee of nutrient quantity though.

Re: Blueprint health protocol

#139

Post by harporoeder »

I wish blueprint was more public and open about the methodology and data. Johnson is doing so many interventions and it would be interesting to have public data for them beyond a periodic aggregate snapshot on the blueprint websites which basically amounts to a marketing page. In comparison someone like Michael Lustgarten (1) publishes nearly everything, documents what intervention they are about to do, do it, and then publish the results.

https://michaellustgarten.com/

Re: Blueprint health protocol

#140

Post by NotGMan »

apwell23 wrote: post #136
Shekelphile wrote: post #31

Earlier quoted context omitted.

There is a very weird lack of interest in slowing down or reversing aging in the scientific/medical community in general. To me it seems like it should be a top priority. Life is extremely short and extending our lives shouldn't be a terribly hard feat given there are plenty of biologically immortal and long lived organisms all over our planet.

> There is a very weird lack of interest in slowing down or reversing aging Uh. We don't even know why we get heartburn and how to treat it. You comment sounds like, why does my toddler lack interest in reading Shakespeare.

There are many people who completely healed it with a drastic dietary change: going low carb, going full carnivore, going vegan, eliminating junk food.
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