131–140 of 200 posts
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> added one cup of coffee caffeine equivalent to his IV. > The IV was much more than the cup of coffee To be clear you mean about same concentration i.e 100mg but higher absorption?
Starbucks is like $5 per 100-200mg. IV caffeine is like $500 per 100-200mg.
Nicotine at least is probably more commonly consumed via alternative means now (in North America, in Vaping would likely be the most common, but there are also patches, gum, lozenges, dip, and snuff. I've never heard of anally consumed nicotine though
I had heard that there's a community of people who insufflate caffeine on Reddit, but this one is news to me. Seems a little funny to go through all the trouble and extreme stigma of injecting yourself with an IV drug, only to pick ground up coffee beans as your poison of choice (!) The study is interesting mostly for the fact that someone tried it, but ultimately the results don't show a very strong effect. I wouldn…
I'm curious if it even absorbs well via the sinuses. From experience with powdered caffeine (mixing with shampoo as a folk treatment for hair loss), it doesn't readily dissolve at room temperature water, though of course it dissolves just fine in hot water, which is why the standard quick extraction from coffee beans involves hot water (cold brew by contrast, involves long periods of steeping for a result that still has less caffeine)
> Every drug seems to have a “right” way to take it. You drink alcohol, smoke tobacco, snort powdered cocaine, inject heroin, and booty bump ecstasy Nicotine at least is probably more commonly consumed via alternative means now (in North America, in Vaping would likely be the most common, but there are also patches, gum, lozenges, dip, and snuff. I've never heard of anally consumed nicotine though
Never heard of blowing smoke up someone's ass? It was literal in the 18th century.
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Hey look something I’m relevant too as a dentist. Tooth decay requires several parameters 1- bacteria 2- bacteria food source 3- acidic environment 4- time We all have the bacteria but the other ones are somewhat controllable. What many people don’t account for is the 4th parameter of contact time. It would be better (for your teeth, not overall health) to rapidly drink several sodas than periodically sip one for sev…
So... how bad is a black coffee I sip on for 30 min? Google says the PH is about 5. No Also: it has definitely stained my teeth. Is there a way to remove the stains that doesn't weaken the enamel?
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Starbucks is like $5 per 100-200mg. IV caffeine is like $500 per 100-200mg.
And pills are like $0 per 100-200mg, so we know why the hospital didn't just use those.
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American healthcare is a mess because of religious shit like this.
Its interesting because its a very specific, recent, and almost uniquely American religious concept, that's written into virtually every aspect of our culture. That is, it seems like nowhere else has the idea of purification through suffering really taken hold at such a widespread level for so long. I'd argue its because its just the flipside of the Prosperity Gospel. If you assume that one's physical conditions are…
And that of course goes back to the Puritans around at America's founding, who were deeply opposed to anybody having fun or enjoying themselves: https://en.wikipedia.org/wiki/Puritans#Behavioral_regulation...
I also recall reading of Calvinists who came to American in the mid-1800s to be free of such things as vaccines and insurance, because they thought those things interfered with God's plan. A plan, apparently, wherein a lot of people suffered while others stood around and quietly gloated that they were god's favorites.
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American healthcare is a mess because of religious shit like this.
It's not religious - it's an overcorrection based on rampant over prescription of pain killers for years.
> Every drug seems to have a “right” way to take it. You drink alcohol, smoke tobacco, snort powdered cocaine, inject heroin, and booty bump ecstasy Nicotine at least is probably more commonly consumed via alternative means now (in North America, in Vaping would likely be the most common, but there are also patches, gum, lozenges, dip, and snuff. I've never heard of anally consumed nicotine though
I've never heard of anally consumed nicotine thoug Never heard of blowing smoke up someone's ass? It was literal in the 18th century.
> ...it was a general mainstream medical procedure used to, among many other things, resuscitate people who were otherwise presumed dead. In fact, it was such a commonly used resuscitation method for drowning victims particularly... Smoke was blown up the rectum by inserting a tube. This tube was connected to a fumigator and a bellows which when compressed forced smoke into the rectum. Sometimes a more direct route to the lungs was taken by forcing the smoke into the nose and mouth, but most physicians felt the rectal method was more effective. The nicotine in the tobacco was thought to stimulate the heart to beat stronger and faster, thus encouraging respiration... Artificial respiration was used if the tobacco enema did not successfully revive them. [1]
So it's not like it was for fun. But I can see how for fast delivery of nicotine, it made perfect sense.
[1] https://gizmodo.com/blowing-smoke-up-your-ass-used-to-be-lit...
I had heard that there's a community of people who insufflate caffeine on Reddit, but this one is news to me. Seems a little funny to go through all the trouble and extreme stigma of injecting yourself with an IV drug, only to pick ground up coffee beans as your poison of choice (!) The study is interesting mostly for the fact that someone tried it, but ultimately the results don't show a very strong effect. I wouldn…
> I had heard that there's a community of people who insufflate caffeine on Reddit I'm curious if it even absorbs well via the sinuses. From experience with powdered caffeine (mixing with shampoo as a folk treatment for hair loss), it doesn't readily dissolve at room temperature water, though of course it dissolves just fine in hot water, which is why the standard quick extraction from coffee beans involves hot water…
Chemists have wonderful words to quantify the exact degree of solubility under various conditions: "sparingly soluble" means it generally takes 30-100ml of solvent to dissolve 1g of the material in question.
So, if you're hip to the quantity of caffeine in your beans (by, perhaps, grinding and boiling 100g and then analytically extracting the mass of relatively pure caffeine with something like DCM, followed by recrystallization in water maybe), you can figure out how much caffeine will be present in your cold brew based on the quantity of solvent.