131–140 of 196 posts
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> Why feed yourself with potential misinformation that you don’t know the true source of and you might never double check? Because I enjoy reading HN?
When you run out of HN, do you hit up ChatGPT?
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> Parkinson's has many forms and many causes. A lot of my family were farmers. I've had close relatives die with severe Parkinsons, primarily those that farmed their whole life. Their theory was that it was really exposure to a lot of toxic farm chemicals. I can imagine Parkinsons turning out to be several different conditions with similar symptoms.
Certain pesticides are confirmed causes of Parkinsons. Don't remember which now, but could look it up.
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Pick up a nicotine addiction. Seriously, it has long been understood that people who smoke have dramatically lower levels of parkinsons. It comes from the neuroprotective properties of nicotine. You don't have to become a smoker, you could theoretically use any of the other forms (vape, gum, patch)
https://www.apdaparkinson.org/article/smoking-and-parkinsons... Smoking and Nicotine addiction are still bad.
Addiction is literally its only downside.
Interesting that big flu outbreaks cause a long term spike in Parkinson's - how much more will be traced back to the impact of viruses? Saw that come up as a worry around Covid, seems the loss of smell/taste is a commonality with Parkison. We will not know for a decade or two though, but these biomarkers might help accelerate measuring the impact.
I am currently struggling with the idea of going back to vaping, having quit 3 years ago following covid, because nicotine has consistently shown to be a strong drug for fending off parkinsons.
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> Parkinson's has many forms and many causes. A lot of my family were farmers. I've had close relatives die with severe Parkinsons, primarily those that farmed their whole life. Their theory was that it was really exposure to a lot of toxic farm chemicals. I can imagine Parkinsons turning out to be several different conditions with similar symptoms.
Certain pesticides are confirmed causes of Parkinsons. Don't remember which now, but could look it up.
People who are very overweight or obese in middle age (35-55) are significantly more likely to develop Parkinson's after 60, even if they lose the weight prior to diagnosis. Now this could be a pure lifestyle-correlation, but my spidey sense suggests it's causative, knowing how causative obesity is for SO MANY other degenerative and chronic diseases.
The best advice you can give anyone, at any time, for the prevention of nearly every poor health outcome we have a name for is and always will be: don't get fat; if you're fat, stop being fat.
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I am currently struggling with the idea of going back to vaping, having quit 3 years ago following covid, because nicotine has consistently shown to be a strong drug for fending off parkinsons.
Would nicotine patches help?
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> Parkinson's has many forms and many causes. A lot of my family were farmers. I've had close relatives die with severe Parkinsons, primarily those that farmed their whole life. Their theory was that it was really exposure to a lot of toxic farm chemicals. I can imagine Parkinsons turning out to be several different conditions with similar symptoms.
Certain pesticides are confirmed causes of Parkinsons. Don't remember which now, but could look it up.
Another is rotenone [2].
https://en.wikipedia.org/wiki/Paraquat https://en.wikipedia.org/wiki/rotenone
Take a look at where you live on the California waterboard website [2] and look for nearby groundwater contamination sites. TCE / PCE contamination sites anywhere near your residence or workplace would put you at risk of getting Parkinsons. I know someone who got it and indeed they lived near a dry-cleaner that was leaching TCE into the groundwater decades ago. The solvent entires your residence through vapor intrusion, especially on the first floor or basement.
[1] https://www.urmc.rochester.edu/news/story/common-dry-cleanin...
[2] https://geotracker.waterboards.ca.gov/map/?CMD=runreport&mya...
Had to start researching this when a family member was recently diagnosed. Parkinson's has many forms and many causes. There's a big divide between Parkinson's _disease_ (idiopathic Parkinson's) and Parkinsonism from a variety of sources - stroke, drug-induced, and so on. There are also other conditions, like progressive supranuclear palsy, that are considered either to masquerade as Parkinsonism or to constitute ano…
> Parkinson's has many forms and many causes. A lot of my family were farmers. I've had close relatives die with severe Parkinsons, primarily those that farmed their whole life. Their theory was that it was really exposure to a lot of toxic farm chemicals. I can imagine Parkinsons turning out to be several different conditions with similar symptoms.
The first study has 3 patients. The second study is a little better, but not by much. Both have the same first author. If this were legitimate, some academic medical center in the US would have picked it up. Parkinson’s is a huge target, and this kind of thing makes a career. This is likely on the same level as horse dewormer for COVID.
That something sounds strange doesn't particularly lead me to question the likelihood of efficacy.
The evidence on something's efficacy leads me to question something's efficacy.