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Fentanyl vaccine tested in rats

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Re: Fentanyl vaccine tested in rats

#131

Earlier quoted context omitted.

The COVID vaccine was designed to reduce the spread of an infectious disease, seems to fit the definition. Is there a different vaccine you refer to?

It used to mean something that actually gave you immunity to something. Like Polio.

No, I think it still meant something that reduces the spread infectious diseases. Like the COVID and Flu vaccines, the Polio vaccine does not provide 100% immunity to 100% of recipients.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974751/

Re: Fentanyl vaccine tested in rats

#132

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

While I agree with you, at the same time, I can't help but think having someone take a pill or shot weekly/monthly/etc is whole lot simpler and easier than fixing the homeless problem, the cost of medical care, and training up (and paying) hundreds of thousands of new mental health professionals, among the dozens and dozens of different reasons people turn to drugs like this to 'escape'.

Re: Fentanyl vaccine tested in rats

#133

Does this prevent death or just the perceived effects of the drug? This could be very dangerous for users who relapse. There is a known pattern of users who get off opioids then relapse and die because their bodies can no longer tolerate the doses that they were used to taking before they quit. This could have a similar effect where users take the drug, don't feel it, and then increase their dose to lethal levels hop…

Can you elaborate on your point of confusion? The mechanism of action was explained in the article.

Re: Fentanyl vaccine tested in rats

#134
post #51

I can imagine such a thing being a double-edged sword, in that it blocks the analgesic effects of the drug as well as the high. Doubly so if this one is a success and they make similar versions targeting other addictive painkillers. I can imagine people taking the vaccine proactively (the normal way people think about vaccines, after all) from the perspective of, "I don't want to become an addict, I better take this!…

If we limit it to people who are using non-prescription drugs, without judgement, this will be the Game Changer they describe. First Heroin, but now cocaine, and even black market cannabis, are being tainted with fentanyl. For that set of people, stopping an accidental poisoning is much more important than potential complications with pain medication later.

> even black market cannabis, are being tainted with fentanyl

I've heard claims like this for decades, it was and probably still is a frequent claim made by cops and teachers giving DARE presentations in American public schools. It doesn't make much sense and never did, why would weed dealers be giving people more drugs than they actually paid for?

It sounds like a cope excuse people come up with on the spot when they don't want to admit what drugs they were actually taking. Ask an alcoholic after a car accident how many drinks they had: "I only had one beer, I don't know how this could have happened!" Ask a fent-head after the OD what happened: "I don't know, I only smoked a little weed!" Yeah right.

inb4 "dealers do it to get people addicted"; it's weed, it sells itself.

Re: Fentanyl vaccine tested in rats

#135

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

Humans were not evolved to resist these kinds of poisons. Nothing like this exists in nature. It’s an extremely potent chemical.

Re: Fentanyl vaccine tested in rats

#136

Earlier quoted context omitted.

The COVID vaccine was designed to reduce the spread of an infectious disease, seems to fit the definition. Is there a different vaccine you refer to?

It used to mean something that actually gave you immunity to something. Like Polio.

No, it didn't. That's "sterilizing immunity", which is a feature of some but not all vaccines. Flu shots, for example, have never given full immunity to the flu, but they've always been vaccines.

In fact, some forms of the polio vaccine can give you polio. https://www.cdc.gov/vaccines/vpd/polio/hcp/vaccine-derived-p...

Re: Fentanyl vaccine tested in rats

#137

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

I think you assume folks want to check out of life because they think fentanyl is a better choice, when instead fentanyl makes folks check out of life. Have you ever spoken with an addict who wants to get clean? It's bleak, they're basically enslaved by the substance. Having a vaccine to break the cycle is a huge boon.

Re: Fentanyl vaccine tested in rats

#138

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

While I agree with you, at the same time, I can't help but think having someone take a pill or shot weekly/monthly/etc is whole lot simpler and easier than fixing the homeless problem, the cost of medical care, and training up (and paying) hundreds of thousands of new mental health professionals, among the dozens and dozens of different reasons people turn to drugs like this to 'escape'.

Do we have a clear picture for where we want this to go in the future? Though not exactly the same, does this start to walk the path towards a "soma" equivalent?

Re: Fentanyl vaccine tested in rats

#139

The real issue here that people don't seem to want to face is the WHY. Why do so many people want to check out of life completely by abusing medicine? If we don't address that nothing is going to stop the drug abuse let alone the relapse and overdose. I'm not talking about "more 12 step" here but more of a Frommian psychoanalytic approach. You are broken because society is broken. You have the ability to change yours…

They’re adding Fentanyl to everything now. I have Burning Man-adjacent friends who take ecstasy once a year at festivals, and they’re terrified of getting a tainted dose. This affects many more people than just those addicted to opiates.

Legalize everything and produce it pharmaceutically, and this problems pretty much disappears.

Re: Fentanyl vaccine tested in rats

#140
post #91

Earlier quoted context omitted.

most fentanyl is manufactured in clandestine labs in mexico and distributed by drug gangs

Most fentanyl is manufactured in China, most illicit fentanyl is produced in Mexico. (nitpick)

i suspect illicit fentanyl greatly outweighs legitimate at this point
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