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Linus Torvalds on mRNA Vaccines

lore.kernel.org

131–140 of 649 posts

Re: Linus Torvalds on mRNA Vaccines

#131
I saw the headline and I thought, "Why do I care what Linus has to say about vaccines? He's just a programmer!"

But then I clicked the link and realized that it was a classic Linus rant! As much as I support codes of conduct and Linus curtailing his asshole behavior regarding technical matters, I think there should be a loophole for anti-vaxxers and other nut jobs who don't care that they might transmit a deadly disease to the immunocompromised or children.

Re: Linus Torvalds on mRNA Vaccines

#132
post #50

Earlier quoted context omitted.

There are a LOT of anti-vaxxers who disingenuously couch their advocacy as "I'm only asking questions". It's no surprise when you've seen a 10:1 ratio of bad actors to good (or worse), one might get a little exasperated. In any case, I've recently been reading Lauren Sompayrac's "How the Immune System Works", and it's a technical overview of the immune system. It's not going to make you into a full blown immunologist…

Is that a book?

Yes: https://www.wiley.com/en-us/How+the+Immune+System+Works%2C+6...

Re: Linus Torvalds on mRNA Vaccines

#133

This is good. Now states are combating such hesitancy by drawing lottery for vaccinated folks. Like, having this magic, absolutely mind boggling potion that prevents serious illness and death *isn't* already the lottery win of our lifetime?? People in India and elsewhere are dying because of lack of vaccines and here we have educated, first world countries struggle to get their citizens vaccinated. Unfortunately sham…

> Like, having this magic, absolutely mind boggling potion that prevents serious illness and death isn't already the lottery win of our lifetime

A lot of it boils down to people not trusting what they're seeing. Frankly, governments have done the world a disservice by speaking before they really had all the information at the start of the pandemic. In Canada at least an insane amount of what was said turned out to be completely false, or worse harmfully false (ie: no masks, isn't airborne, ect). As a result, lots of people see what looks like the "story changing", and distrust anything coming out of their government, and experts, at this point. I think if we approach the problem with that in mind we might win more people over than telling them "listen to experts", since for the past year and a half experts have been wrong almost as often as they have been right.

Re: Linus Torvalds on mRNA Vaccines

#134
post #94
post #15

Absolutely agree with everything Linus says here. But I'm almost equally concerned that there's an awful lot of people on the pro-science bandwagon who don't actually support science, but simply don't tolerate dissent or questioning, and that's unscientific and potentially harmful too. I scanned most of the Pfizer trial and was wondering why we expected the immunity after the vaccine to last longer than natural immun…

Ever since the pandemic started, useful information was few and far between. I know that numbers scare people, but so much of this is basic risk assessment. The facts are extremely pro-vaccination, but good luck finding them! For example, the whole thrombosis / Astra-Zeneca issue, which was a big deal here in Germany. Lots of articles and discussions. Everyone was saying "don't use it on young people", but I don't ev…

Typically a vaccine is aborted if it kills just a single person during its clinical trial.

Re: Linus Torvalds on mRNA Vaccines

#135
post #78

Earlier quoted context omitted.

TL;DR you heard claims of vaccines' prophylactic effect lasting for years, from somewhere unnamed, and you correctly heard from people in the medical field that no one has any idea of how long it'll last, we're barely 6 months into have a sizable cohort to analyze this with in the US, which itself is far ahead of most of the world. Another massive factor is we have no idea how fast the virus will mutate. Edit: oh, th…

We have a fairly good idea about how it will mutate actually. COVID is probably one of the most heavily studied and sequenced viruses ever, and a lot of research has been published on likely mutagenic pathways. The media as always has sensationalized every new strain found and their behaviour is cause for concern, but researchers have not been sounding the alarm over possible vaccine escape - the evidence points to t…

Do you have anything on the Astra-Zenaca vaccine and how well it works against the do called "South-African" variant. There was a story that they'd stopped a trial because the results were so bad. Do we have any harder data?

Re: Linus Torvalds on mRNA Vaccines

#136
post #26

I cant +1 this enough. Thank you, Linus for standing up to the wealth of misinformation out there and holding his ground.

> Thank you, Linus for standing up to the wealth of misinformation out there and holding his ground. Being a pompous ass might feel good, especially when you think you are (or you actually are) smarter than your opponent, but it won't sway anyone. In fact, it does quite the opposite. If you're seriously trying to convince someone they're wrong, you need to be kind, be patient, and have a calm, productive discussion -…

> explaining how traditional vaccines work, how mRNA works, how DNA works, and so on.

1) You can't reason someone out of a position they didn't reason themselves into.

2) Lots of people do not have the brain power to understand vaccines and they will simply follow the herd.

Part of the reason anti-vax gets such a boost is because it is considered an "acceptable" position to follow by "respectable" people like the "natural is the only good stuff" dipshits in Marin county (who regularly give us Measles and Pertussis outbreaks).

Yes, you can try to reason with individuals. However, you also need to make stupid positions socially unacceptable so that the part of the herd who don't have the capacity to understand don't go following people willing to lead them off a cliff.

Re: Linus Torvalds on mRNA Vaccines

#137

mRNA doesn't change your genetic sequence in any way. It is the exact same intermediate - and temporary - kind of material that your cells generate internally all the time as part of your normal cell processes The m in mRNA stands for messenger. I'm failing to find anything I consider to be a succinct explanation in layman's terms (other than the one in the piece under discussion: all that the mRNA vaccines do is to…

I & others tried about 6 months ago in this thread that asked a similar Q.

https://news.ycombinator.com/item?id=25319117

Re: Linus Torvalds on mRNA Vaccines

#138
post #50
post #15

Absolutely agree with everything Linus says here. But I'm almost equally concerned that there's an awful lot of people on the pro-science bandwagon who don't actually support science, but simply don't tolerate dissent or questioning, and that's unscientific and potentially harmful too. I scanned most of the Pfizer trial and was wondering why we expected the immunity after the vaccine to last longer than natural immun…

There are a LOT of anti-vaxxers who disingenuously couch their advocacy as "I'm only asking questions". It's no surprise when you've seen a 10:1 ratio of bad actors to good (or worse), one might get a little exasperated. In any case, I've recently been reading Lauren Sompayrac's "How the Immune System Works", and it's a technical overview of the immune system. It's not going to make you into a full blown immunologist…

> There are a LOT of anti-vaxxers who disingenuously couch their advocacy as "I'm only asking questions"

https://en.wikipedia.org/wiki/Sealioning

Re: Linus Torvalds on mRNA Vaccines

#139
post #15

Absolutely agree with everything Linus says here. But I'm almost equally concerned that there's an awful lot of people on the pro-science bandwagon who don't actually support science, but simply don't tolerate dissent or questioning, and that's unscientific and potentially harmful too. I scanned most of the Pfizer trial and was wondering why we expected the immunity after the vaccine to last longer than natural immun…

> there's an awful lot of people on the pro-science bandwagon who don't actually support science, but simply don't tolerate dissent or questioning

I think the problem is that its 10-100x as expensive to refute a misinformed statement than it is to make one. So the plea for the small pool of genuinely authoritative / informed people to invest two orders of magnitude more effort patiently and kindly explaining misinformation to people just isn't practical in any meaningful sense.

We don't need to persuade them. They aren't persuadable, and in many cases they aren't there in good faith in the first place. We do need them to stop spreading lies and causing extreme harm to their communities. The most effective way to do that is to teach them that their actions - spreading obvious misinformation - are as offensive as they actually are (in that they actively harm people).

Re: Linus Torvalds on mRNA Vaccines

#140
Just to clear one thing:

Vaccines actually do edit the genetic code, but only of some select B-cells. And so does any other antigen that your body develops antibodies for. The process is very complicated and beautiful, and is pretty much exactly the same as in plenty of other multicellular life forms.

If you've ever wondered what's the "storage format" for all the recipes for all the different antibodies that your body produces, that is how does your body even remember infections from years ago - it's DNA, and the recipes are generated via a massively sped up internal evolution, mediated by T cells. The process of maturing B-cells is kind of similar to machine learning. The matured B-cells are then safely stashed away in the bone marrow. Really remarkable stuff.

(I understand that Linus meant that the vaccine mRNA is not reverse transcribed into the host DNA, and that is of course the case. Also, a side note: the human genome is littered with viral genetic material accumulated over time, god knows if it's for good or for bad, we're still too dumb to answer such questions)

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