131–140 of 266 posts
> Patients were administered oral vitamin D3 1000 IU OD I've seen multiple sources say that 1000 IU of vit D is usually insufficient to boost levels, with suggestions of up to 5000 a day. My mothers doctor put her up to 2000 a day because 1000 did nothing to her levels, which were already low.
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I wouldn't be surprised if quarantine is leading to an historic spike in D deficiency.
I suspect it's exactly the opposite. During quarantine, you have far fewer people spending most of their waking hours in huge concrete coffins. How many people even get to see the sun during a typical workday, much less spend time in direct sunlight?
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I wouldn't be surprised if quarantine is leading to an historic spike in D deficiency.
I suspect it's exactly the opposite. During quarantine, you have far fewer people spending most of their waking hours in huge concrete coffins. How many people even get to see the sun during a typical workday, much less spend time in direct sunlight?
I moved from Brazil to the UK 6 years ago and have since developed a semi-transparent quality on my skin.
1 month into the quarantine and I have a great tan and look like a healthy human. The healthy part is probably in part due to better sleep and a lot less exposure to pollution but sunlight definitely helps.
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The largest dosage of D3 I can find on Amazon is 5000 IU in a 240 capsule bottle. To take 60000 IU, you'd have to take a dozen capsules daily, getting a new bottle every 20 days, probably multiple times. While possible, it does seem unlikely.
I'm currently taking 60K IU D3. The dosage is 1 capsule a week, for 8 weeks, and the capsules come 4 to a pack. This is followed by a maintenance dosage of 1 60k capsule once a month.
I'm curious why an acute high dose would be preferable over a lower dose taken daily.
> Patients were administered oral vitamin D3 1000 IU OD I've seen multiple sources say that 1000 IU of vit D is usually insufficient to boost levels, with suggestions of up to 5000 a day. My mothers doctor put her up to 2000 a day because 1000 did nothing to her levels, which were already low.
How did the doctor know her vitamin levels were low? I once asked a doctor if the vitamins in our body can be measured, and he said it can't be done, is not something you can measure.
> The most accurate way to measure how much vitamin D is in your body is the 25-hydroxy vitamin D blood test.
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You are right and it is no secret: - 40% of US Americans are B12 deficient https://www.livekindly.co/b12-deficiency-genetic-makeup/#:~:... . - 42% are Vitamin D deficient: https://www.cantonmercy.org/healthchat/42-percent-of-america... . - up to 50% are Magnesium deficient: https://www.sciencedaily.com/releases/2018/02/180226122548.h... - 10 - 20% of women are iron deficient: https://www.aafp.org/afp/2007/0301/p671.h…
I've always wondered about this deficiency thing. How is it defined, and does it make any sense to claim that such a large part of the population is deficient? Shouldn't that be considered "normal" (excluding the truly pathological cases), as opposed to "above-average"?
[...]
> Significantly fewer DMB patients than controls required initiation of oxygen therapy subsequently throughout their hospitalization (17.6% vs 61.5%, P=0.006).
Is this a joke? Patients not requiring oxygen upon admission were less likely to require it later on and they try to pin it on their snake oil?
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I've always wondered about this deficiency thing. How is it defined, and does it make any sense to claim that such a large part of the population is deficient? Shouldn't that be considered "normal" (excluding the truly pathological cases), as opposed to "above-average"?
At least for Vit D and B12, the healthy levels were determined by establishing levels in "healthy" cohorts. Deficiency diseases for both of these vitamins are relatively rare, so it is easier to establish a wider "safe" range, rather than "deficiency" ranges. There's been a great deal of debate on safe Vit D levels, and the consensus (such as it is) is that a serum level of 30 ng/mL is likely optimal. Yet there are m…
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440113/
> There's been a great deal of debate on safe Vit D levels, and the consensus (such as it is) is that a serum level of 30 ng/mL is likely optimal.
If you look at dark-skinned hunter-gatherer tribes which are living in a way closer to our common ancestors, the "natural" Vitamin-D levels in their relatively sunny environment is more like 40 to 50. The body seems regulate Vitamin-D production up that level, so that's probably closer to optimal than 30.
I wonder, when I see stories about studies about treating patients with basic nutrients and vitamins, if a root-cause to consider is that our standard diets are so deprived of essential vitamins and minerals that "treating" someone with what they have been missing causes the body to simply function the way it's supposed to. I haven't read the full study but if it takes into account what someone's diet was prior to th…
You are right and it is no secret: - 40% of US Americans are B12 deficient https://www.livekindly.co/b12-deficiency-genetic-makeup/#:~:... . - 42% are Vitamin D deficient: https://www.cantonmercy.org/healthchat/42-percent-of-america... . - up to 50% are Magnesium deficient: https://www.sciencedaily.com/releases/2018/02/180226122548.h... - 10 - 20% of women are iron deficient: https://www.aafp.org/afp/2007/0301/p671.h…
Remember that half of all research papers are probably wrong and most of medical research is wrong, according to John Ioannidis:
"Why Most Published Research Findings Are False" by John P. A. Ioannidis:
https://journals.plos.org/plosmedicine/article?id=10.1371/jo...
Lighter reading on this topic:
"Lies, Damned Lies, and Medical Science" by David H. Freedman (who later wrote an excellent book on this topic, see below for link):
https://www.theatlantic.com/magazine/archive/2010/11/lies-da...
"A Researcher’s Claim: 90% of Medical Research Is Wrong" by Maia Szalavitz:
https://healthland.time.com/2010/10/20/a-researchers-claim-9...
And in these days of COVID, HCQ, Remdesevir, crisis, civil unrest and crime I cannot recommend enough David H. Freedman's book titled:
"Wrong: Why experts[1] keep failing us"
with the subtitle
[1]"Scientists, finance wizards, doctors, relationship gurus, celebrity CEOs, ... consultants, health officials and more"
https://www.amazon.com/Wrong-us-Scientists-relationship-cons...
Freedman examines thoroughly the issues that John P. A. Ioannidis has raised.
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Chromebooks are good for a lot of things (especially entertaining young kids) and are cheap. I find the quality to be much better than kid tablets which are terribly glitchy. A Windows laptop with only 2 GB of RAM (shocked you could still get that little) is like $400 and much larger than a Chromebook. Powerstrips are necessary for makeshift home offices which are now everywhere. Hairclippers are important for people…
Are you a GPT-2 bot or something?