Earlier quoted context omitted.
Oof. Funny you mention that. I just bought it, but haven’t read it yet; only flipped through a little. It’s clearly a dangerous topic for me and if I can find the discipline in myself, I’ll return it before it’s too late. Thanks for the thoughts, and the other comments here are all very lucid. These points aren’t lost on me, and I expect plenty of truth to them.
Norbert Wiener's book "Invention" is another on a similar topic. He argues that research should be driven more by the interests of individual researchers rather than managers and bureaucrats.
And one thing to consider: a researcher's mind is an inquisitive mind that will "dig" even in directions nobody really cares about, don't help humanity, etc.
The one upside of someone else giving the direction is that you can be sure that there will be some concrete benefit from it. The downside is that it's mostly about money and power...