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Well that's definitely a take. I'm not going to be the first in line to defend government, but more often than not I'm seeing friends and family getting chased out of the hospital BEFORE they should be.
New HIV vaccine shows unprecedented success in preclinical study
121–130 of 325 posts
Re: New HIV vaccine shows unprecedented success in preclinical study
#122Earlier quoted context omitted.
Well, they kind of all work that way, it's just that most of the curriculum occurs naturally through interactions with wild pathogens
From what I understand, random interactions with wild pathogens can prime the immune system in the wrong way, leading it down the wrong path. This is why some people can get lucky with immunity and be super resistant to flu, because they happened to luck into a response that targets a common factor in most flu strains. Other people have bad luck and target some area that mutates frequently, and they proceed to get wa…
As someone whose had rheumatic fever, your immune system can definitely prime itself for the wrong target.
Re: New HIV vaccine shows unprecedented success in preclinical study
#123Earlier quoted context omitted.
It's still killing people like crazy (and spreading) in undeveloped nations. The new drugs are un-cheap. Also, I believe that we just DOGEd our only vehicle for distributing these to underdeveloped nations.
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Considering his family history and his weird eugenic tirades, perhaps that was the intended effect to complete his fantasy cosplaying as a Roman general.
Re: New HIV vaccine shows unprecedented success in preclinical study
#124Earlier quoted context omitted.
Taking teen pregnancy as an example: we have the tools to avoid it. We have condoms, we have birth control, we have the morning after pill, we have abortion. We have all the tools -- are more tools really going to help? The fact that teen pregnancy is still an issue is not because we lack the tools to solve it. HIV prevention is similar. We already have the tools. We have condoms. We have PrEP. Sure, a vaccine would…
All your arguments are sound, and I'm still missing your point. Pharma is interested in doing pharma, indeed. But who's interested in your solution, assuming you have one? A significant part of the current electorate (internationally, even) seems to abhor sex ed, condoms, abortions and all that. So tell me again please how you suggest we address teen pregnancy - in THIS world.
The person I was responding to says "HIV is not a solved problem" and "we need a new tool to solve it, a vaccine!"
My argument is simply that new tools are great, but it's not what's going to solve the HIV problem. Distribution, cost, access, stigma, etc are the larger problems to deal with. (We need to solve all the reasons why people aren't using the existing tools)
Re: New HIV vaccine shows unprecedented success in preclinical study
#125Earlier quoted context omitted.
You are extremely unlikely to get HIV from anything other than risky sex. That's what "risk" means: it's another word for "probability," just a probability of negative outcomes. These probabilities are known: https://www.aidsmap.com/about-hiv/estimated-hiv-risk-exposur... Some of that table is already mitigated: we test blood for HIV, so transmission by blood transfusion is unlikely. Transmission by pregnancy is less…
> Is someone irresponsible enough to pursue causal, unprotected sex with random partners also likely to be responsible enough to visit a doctor proactively and comply with a prep regimen? Yeah, me. What a wild statement to make. It’s a big world out there, my friend.
You may have missed the word likely.
Re: New HIV vaccine shows unprecedented success in preclinical study
#126Earlier quoted context omitted.
Ad-hoc use of PrEP just requires that you take a double dose 1 hour prior to potential exposure, and follow up with another double dose 24 hours later, at least with the versions commonly prescribed to sexually active groups in my area. I agree that a vaccine is another game-changer, but it’s extremely important that we don’t spread misinformation about the efficacy and convenience of PrEP. In developed societies, it…
Does this double dose completely prevent infection?
The evidence I’m aware of suggests that this method (on-demand or event-based PrEP) is broadly as effective as daily PrEP (though it’s not suitable for vaginal sex). I believe adherence rates are generally lower though, as people can find the instructions confusing, and it’s obviously easier to mis-dose than a daily regimen.
Re: New HIV vaccine shows unprecedented success in preclinical study
#127Earlier quoted context omitted.
No, it's from the cost of living being so high that people are delaying having kids.
Worldwide the main thing that correlates to having less kids is being more educated. High cost of living correlates with more kids, not less.
Worldwide being more educated means higher cost of living. Nowhere in the world is there a country with high cost of living and high birthrates
Re: New HIV vaccine shows unprecedented success in preclinical study
#128Earlier quoted context omitted.
Which is in fact panic that teens are not having enough children, because that's where we have seen big drops... This whole "panic" seemed weird from the start, but once it becomes clear that it's from the lack of teen pregnancies it takes on an even creepier Epstein-like oddness.
No, it's from the cost of living being so high that people are delaying having kids.
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Re: New HIV vaccine shows unprecedented success in preclinical study
#129Earlier quoted context omitted.
Worldwide the main thing that correlates to having less kids is being more educated. High cost of living correlates with more kids, not less.
Worldwide being more educated means higher cost of living. Nowhere in the world is there a country with high cost of living and high birthrates
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Re: New HIV vaccine shows unprecedented success in preclinical study
#130Earlier quoted context omitted.
I was 16 when Magic Johnson announced he had AIDS. That was the first time it felt real to me. I remember a couple of friends crying because we all thought he would be dead in 1-2 years. And here he is and seems to be living a normal life.
He doesn't have AIDS, he's HIV-positive.
I understand the difference between those statements, but confess that I'm not clear on the important distinction. Are there situations where untreated HIV doesn't progress to AIDS? Is the virus more transmissible in someone with AIDS than someone who's still at the HIV-positive stage?
Asking here because I don't know, and I think an answer might help others know, too.
(And to clarify, I genuinely don't know, and I'm asking from a supportive POV.)