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The Causes of Long Covid

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Re: The Causes of Long Covid

#121

Post by saulpw »

whiskey_ranger wrote: post #94

Covid almost killed me. I distinctly remember feeling near death when the hospital attempted a last-ditch effort with a transfusion. I don’t remember all of the details, but I know that someone, somewhere, saved my life. And I’ve done fuck all with that gift — it’s been almost five years. Personally, the only long Covid symptom I know of is that I have a coughing fit after every meal (and sometimes during). Some food…

> coughing fit after every meal (and sometimes during).

This might be stomach acid aspirating into your lungs, from GERD or similar caused/exacerbated by Covid, and that may have negative consequences for your health apart from the coughing.

Re: The Causes of Long Covid

#122

Post by timr »

kranke155 wrote: post #113
timr wrote: post #108

Earlier quoted context omitted.

> the controls also lived through lockdown. If this is the rigorous analysis you’re bringing to the studies you read, I’m not surprised none of them pass the muster. You've missed the point. I'm not suggesting that the other factor or factors has to be "lockdown". I'm just giving examples that illustrate the idea: even if you assume that the differences between the control and the experimental group are non-random an…

Yes of course. It’s lockdown and now no lockdown. Could be anything. All observational studies are wrong. The stated limitations are fatal flaws. You heard it here first in HN. All medical research is fatally flawed, says user “timr”. Good luck with that.

> All observational studies are wrong...You heard it here first in HN.

No, but most of them are wrong, and all of them need to be treated with an incredibly high degree of skepticism. This is critical review 101. When you push on this paper, even lightly, it falls over.

Not all papers are bad, but this one is bad, and while there are a great many well-done studies in the world, the subject of "long covid", to date, has essentially ~none of them.

Re: The Causes of Long Covid

#123

Post by Llamamoe »

brational wrote: post #97
lend000 wrote: post #22

I had a long process with this that mostly manifested as exercise intolerance and general inflammation/discomfort, and sleep struggles. I made no progress for 2 years, lost most of my muscle (I had been very active before) and started thinking "is this how it's going to be forever?". After not finding anything promising from traditional medicine or supplements, I finally made some dramatic life changes. I'm fully pas…

Having gone through this too, I also had to accept that a lot (not all!) of it was in my head and made worse by it. When I convinced myself that “this will pass” and “this slow steady plan will get me out of this eventually” was when I finally saw regular progress (progress, not immediate relief).

I'm glad that this was the case for you, but presenting it as an universal truth is extremely cruel and harmful to people for whom it is not, and you should be really careful with phrasing. Statements like these is why people's symptoms are not being taken seriously.

Re: The Causes of Long Covid

#125

Post by picofarad »

ragequittah wrote: post #72
thrirnfjri wrote: post #65

Earlier quoted context omitted.

[flagged]

You're proving the idea that the science wins out though. The vaccine that caused problems in a vanishingly small amount of people was almost instantly recalled. I believe here in Canada we started giving it to people in February and stopped in March. The signal was so clear even though it was something like 1 in 50,000 people who had a problem. We have giant populations of people who refused the vaccines. We also ha…

> The trials for the Pfizer vaccine came back as 95% effective.

Actually 99%

But it turned out it was only 37% effective and then they stopped reporting the efficacy. On to boosters!

Re: The Causes of Long Covid

#126

Post by defrost »

picofarad wrote: post #125
ragequittah wrote: post #72

Earlier quoted context omitted.

You're proving the idea that the science wins out though. The vaccine that caused problems in a vanishingly small amount of people was almost instantly recalled. I believe here in Canada we started giving it to people in February and stopped in March. The signal was so clear even though it was something like 1 in 50,000 people who had a problem. We have giant populations of people who refused the vaccines. We also ha…

> The trials for the Pfizer vaccine came back as 95% effective. Actually 99% But it turned out it was only 37% effective and then they stopped reporting the efficacy. On to boosters!

It was 95% and it was documented in trials.

And then the COVID virus mutated, reducing the efficacy of that specific vaccine variant.

Current real-world data shows latest updated Pfizer-BioNTech COVID-19 vaccines reduce the risk of hospitalization by roughly 50% to 60% and lower the risk of urgent care or emergency department visits by 50% to 75%.

Yale medical regularly updates efficacy data on a roughly six month(? IIRC) cycle, other countries also routinely publish.

Re: The Causes of Long Covid

#127

Post by kranke155 »

timr wrote: post #122
kranke155 wrote: post #113

Earlier quoted context omitted.

Yes of course. It’s lockdown and now no lockdown. Could be anything. All observational studies are wrong. The stated limitations are fatal flaws. You heard it here first in HN. All medical research is fatally flawed, says user “timr”. Good luck with that.

> All observational studies are wrong...You heard it here first in HN. No, but most of them are wrong, and all of them need to be treated with an incredibly high degree of skepticism. This is critical review 101. When you push on this paper, even lightly, it falls over. Not all papers are bad, but this one is bad, and while there are a great many well-done studies in the world, the subject of "long covid", to date, h…

I knew this would be the conclusion. Again - good luck. You are always right.

If you’re right and everyone else is wrong about hundreds if not thousands of studies, then you should be writing a book, not comments in HN.

We started at “some studies have errors” and we ended in “an entire field of research is wrong”.

You have already decided the field has no valid studies. Even when given dozens of examples you picked one and made up a series of points about one study. You made mistakes, never admitted it, and now are calling into question an entire field of medical research.

Again. Good luck with that.

Re: The Causes of Long Covid

#128

Post by exmadscientist »

lend000 wrote: post #112
_nalply wrote: post #73

Earlier quoted context omitted.

How do you manage zone 5 cardio 4x a week without PEM? I thought up to 3x a week and never consecutive days is the maximum.

Zone 5 is usually 1-2 minutes out of a longer 30 minute cardio session for me, I do it as a final sprint. I am not talking about repeated hill sprints where you would get 10+ minutes of zone 5 cardio in a session, which I agree would not be something a normal person should do 4x/week. From my own experience, it seems like hitting that Zone 5 briefly is a good nervous system reset (overrides any dysfunctional breathin…

> hitting that Zone 5 briefly is a good nervous system reset

I ended up doing this inadvertently earlier this week due to some medication side effects (yay akathisia!) making me want to go outside and just seriously run fast, including up the nasty hill nearby. Which I could, so I did. I'm amazed at how much it seems to have helped, for how simple it was. (Another one from the past, though for different situations: alternating hot and cold showers.)

Re: The Causes of Long Covid

#129

Post by genewitch »

defrost wrote: post #126
picofarad wrote: post #125

Earlier quoted context omitted.

> The trials for the Pfizer vaccine came back as 95% effective. Actually 99% But it turned out it was only 37% effective and then they stopped reporting the efficacy. On to boosters!

It was 95% and it was documented in trials. And then the COVID virus mutated, reducing the efficacy of that specific vaccine variant. Current real-world data shows latest updated Pfizer-BioNTech COVID-19 vaccines reduce the risk of hospitalization by roughly 50% to 60% and lower the risk of urgent care or emergency department visits by 50% to 75%. Yale medical regularly updates efficacy data on a roughly six month(?…

well, you might be right oh wait https://nextcloud.projectftm.com/index.php/s/vaccine100perce...

stand up when any of the numbers you mention show up!

* note: you have to wait a bit since everyone said it was 100% effective

Re: The Causes of Long Covid

#130

Post by defrost »

genewitch wrote: post #129
defrost wrote: post #126

Earlier quoted context omitted.

It was 95% and it was documented in trials. And then the COVID virus mutated, reducing the efficacy of that specific vaccine variant. Current real-world data shows latest updated Pfizer-BioNTech COVID-19 vaccines reduce the risk of hospitalization by roughly 50% to 60% and lower the risk of urgent care or emergency department visits by 50% to 75%. Yale medical regularly updates efficacy data on a roughly six month(?…

well, you might be right oh wait https://nextcloud.projectftm.com/index.php/s/vaccine100perce... stand up when any of the numbers you mention show up! * note: you have to wait a bit since everyone said it was 100% effective

Have a real source?

Maybe everyone you talked to or US press perhaps - here we ran with medical trials and epidemiologists.

> everyone said it was 100% effective

You're quoting idiots then - or second / third hand press reporting, or US/UK officials pressured by the US/UK admin of the time.

Not everyone lived in a politically captured shitshow.

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