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Peptides: where to begin?

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Re: Peptides: where to begin?

#121

Post by jmye »

pedalpete wrote: post #40
jmye wrote: post #7

Earlier quoted context omitted.

> Another point I could raise is that telemedicine has turned the entire prescription system into nothing more than a parasitic middleman/gatekeeper. I’m curious what you mean by this. I’m not sure what you mean by “prescription system” specifically.

The "perscription system" used to be that you'd have to go see a doctor, the doctor knew who you were, and would make decisions on what prescriptions/medications you should be given. Due to drug advertising rules, the prescription system has been turned on its head, and the patient now goes to their doctor asking for a specific prescription. Telemedicine took advantage of this and has effectively removed the middlema…

> Telemedicine took advantage of this and has effectively removed the middleman (the doctor) in many cases and you just sign-up look at a person on a camera, and get your drugs sent to you.

This is only true for a handful of drugs that are basically OTC already (or that have OTC formulations). Additionally, telemedicine didn’t take advantage of drug advertising- that’s an odd assertion.

Re: Peptides: where to begin?

#123

Post by jmye »

Bender wrote: post #14
jmye wrote: post #13

Earlier quoted context omitted.

> Drugs risks do not enter into the picture given the fact I can buy ammonia and bleach along with a myriad of other dangerous compounds. This is a deeply weird take. You think anyone ought to be able to buy, for instance, warfarin and freely take it without a doctor’s involvement? We should let parents self-diagnose diabetes and administer insulin without a prescription or discussion? We should just hope that patien…

You think anyone ought to be able to buy, for instance, warfarin and freely take it without a doctor’s involvement? Yes.

Why? Why, specifically, do you think an adult without HF should be able to buy a random drug, likely by accident, and start taking it?

I guess I don’t hate everyone else enough to agree with that.

Re: Peptides: where to begin?

#124

Post by jmye »

cm2012 wrote: post #59
Bender wrote: post #14

Earlier quoted context omitted.

You think anyone ought to be able to buy, for instance, warfarin and freely take it without a doctor’s involvement? Yes.

Triple yes! Most of the people buying it have been buying it and using it for years.

Why do you think only the people taking it would be buying it?

Re: Peptides: where to begin?

#125

Post by 7e »

A_D_E_P_T wrote: post #2

Lowe has a point, but the FDA has painted itself into a corner by (a) forcing up the costs and the various bureaucratic demands associated with clinical trials, (b) allowing drug advertising , but then forcing those comical "may cause death" disclaimers, both of which have become totally ubiquitous, and (c) inconsistently following its own rules, and in some cases flouting its own rules. At this point, broscience is…

The FDA didn’t push up clinical trial costs, thalidomide did.

Re: Peptides: where to begin?

#126

Post by kube-system »

phil21 wrote: post #97
kube-system wrote: post #75

Earlier quoted context omitted.

It's cheaper for most people to get the prescription written at a PCP. The advantage to a telehealth is not getting the prescription written -- it's that they'll fill it for cheap through a tiny compounding pharmacy that is making it, technically illegally, but are small enough to be off the FDAs enforcement radar for the moment.

I have used both my PCP and telehealth for prescription writing, never once have I used a compounding pharmacy. It's slightly cheaper for me to use telehealth vs. billing through my insurance. The downside is it doesn't go towards my deductible of course. The stuff you are describing are entire supply chains of a sort where you want a GLP-1 or perhaps a few other things like TRT. Those you are signing up for the drug…

> It's slightly cheaper for me to use telehealth vs. billing through my insurance.

How? Usually PCP visit are cheap and everyone gets one for free.

> HIMS/HERS/etc. and their smaller ilk are super popular, but they are the tip of the iceberg. > Telehealth providers can certainly work with compounding pharmacies but not necessarily.

Yeah I’m aware there are a whole host of services telehealths provide but the primary reason people use them for GLP1s is to avoid the name brand cost.

Re: Peptides: where to begin?

#127

Post by Zetaphor »

GenerWork wrote: post #10
A_D_E_P_T wrote: post #2

Lowe has a point, but the FDA has painted itself into a corner by (a) forcing up the costs and the various bureaucratic demands associated with clinical trials, (b) allowing drug advertising , but then forcing those comical "may cause death" disclaimers, both of which have become totally ubiquitous, and (c) inconsistently following its own rules, and in some cases flouting its own rules. At this point, broscience is…

To your first point, if you know where to look, you can get tens of vials of GLP-1s that have much higher dosing per vial for cheaper than you can get a third of the amount on the grey market. A lot of these sites even have purity testing to soothe consumers worries that they're getting garbage. For your third point, you have the FDA limiting HGH, yet you can buy the growth horomone releasing factor peptides (tesamor…

Many of us would appreciate if you could share one of those reputable vendors with such cheap prices

Re: Peptides: where to begin?

#128

Post by solenoid0937 »

fragmede wrote: post #51
Bender wrote: post #6

Earlier quoted context omitted.

I agree with some of this. There are most certainly orally active peptides such as BPC-157 and its replacement PDA penta deca arginate that can repair the gut and still circulate throughout the body especially in those with leaky gut. People with leaky gut should be able to buy a clean source of BPC-157 or PDA without a prescription and without visiting dark alleys. It is very safe and tolerable. GLP's are all the ra…

Injected BPC-157 to a wound is a magic healing potion as far as I'm concerned. That it's not more broadly available is a crime, imo. If I had a billion dollars, I'd push so many things through the FDA.

If you had a billion dollars, you would need many billions more to push even a single thing through the FDA!

Re: Peptides: where to begin?

#129

Post by Nursie »

diath wrote: post #15

> My patient is refusing a drug studied in 170,000 people because of side effects that a 124,000-person analysis just confirmed do not exist — while injecting a compound studied in 14 humans, from unregulated sources, based on the recommendation of someone who profits from selling it. She’s probably not the only one. And those using it believe they are “doing their own research.” Ok, and? At worst you waste a couple…

> At worst you waste a couple hundred dollars

At worst you inject unknown substances into your bloodstream that could do more or less anything.

Re: Peptides: where to begin?

#130

Post by deinonychus »

cjbgkagh wrote: post #65

Peptides are a revolution and you don't need to know how they work to know that they work (for various people for various conditions). There is a tension between empiricism and fundamentalism with much of medical science focusing on fundamentalism. Now with the ability to collect and search large amounts of empirical data and communicate it peer-to-peer people are picking up on a lot of things that work without knowi…

can you talk about how semaglutide improves ME?
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