Earlier quoted context omitted.
Maybe someone can make a curated wiki page of people's unfinished and/or abandoned projects so everyone can put theirs there? (Oh wait, that's just github.)
except you said curated :) I actually love this part of github; it reminds me of the old internet, full of under construction Geocities pages and other half-baked projects. It's the polar opposite of today's bland, instagram-perfect same-same internet.
Side projects I've built since 2009
121–130 of 146 posts
Re: Side projects I've built since 2009
#122Earlier quoted context omitted.
100% not true in my case and probably not true in the generally case, it’s a common misattribution. The cause of mine is hEDS which has ME/CFS as a comorbidity. I’ve done a WGS and found that I have 2 TNXB SNPs. By my math a lot of ‘burnout’ especially in tech is related to TNXB or CYP21A2 SNPs. The treatments that I take specifically targets IL-1B cytokines that are linked to brain fog. I was able to predict that I…
I'm going through a similar investigation. EDS + ME/CFS are the main suspects. Could live with the symptoms for very long, but they got too severe after covid (otherwise I would probably still be living with them). Is the treatment working out well for you?
For the IL-1B I take high doses of D3, TUDCA, and DIM. For the dysautonomia aspect I take Low Dose Naltrexone, a lower dose of modafinil in the morning and amitryptiline at night. I prefer weaker psychopharmacology ligands as it’s preferable to work with the natural rhythms of the body instead of fighting them.
I have a strict near zero sugar diet that’s high in kale. I take a low dose of semaglutide (ozempic) which has been one of the best meds I’ve tried. I make sure I get enough UV exposure. I’ve done Test Cyp and Ipamorelin/ModGRF and they do help a lot but I stopped taking them when semaglutide worked so well. I highly suspect people with hEDS are highly sensitive to semaglutide and should start and stay on much lower doses (1/10th) otherwise they’re near guaranteed to have a bad time.
I’m mostly interested in the TNXB subtype of hEDS which seems to have some weird comorbidities, like an intolerance to noise, a touch of ADHD, obstinate personality, difficulty falling asleep, local and general anesthetic resistance, and an unusually high IQ. There is an unusual reaction to medications with most medications working less than expected.
A good list of comorbidities that could help make a self diagnosis; https://ohtwist.com/about-eds/comorbidities
Re: Side projects I've built since 2009
#123Earlier quoted context omitted.
I don't suppose you're using LLMs for coding? The number of my older friends who've found energy for side-projects since LLM coding became a thing is very notable In the most extreme case: a new father of twins just uses his IDE and home projector to put up the work on the wall and builds little things by voice and reading, as he's home with his daughters. It's pretty eye-opening. Obviously, he won't want to divide h…
I've never touched an LLM and won't use AI. Everything I ever have and will make is hand crafted.
Re: Side projects I've built since 2009
#124Earlier quoted context omitted.
Not disdain, just skepticism. One too many experts have gravely misled me to damaging effect.
The psychosomatic view of ME/CFS was and in many places remains the expert opinion and one that I agree is misleading and damaging. It was pushed by a highly influential team of British psychiatrists. Many countries still prescribe exercise as the official treatment which is horrific, especially when MAID is given as an alternative. I’m understand of skepticism. My position is that of a subset of the patient communit…
Lotta folks died, because of that.
Re: Side projects I've built since 2009
#125Earlier quoted context omitted.
I’ve been doing my ‘side’ project as my day job for 5 years, 10 productive hours a day, 7 days a week. Sunday is dedicated to side side projects for experimental ideas that are not on the critical path. When working a normal job I could only work part time due to burnout that I later found out was in reality ME/CFS. After a Covid vaccine injury (long covid) I had to pause work for a few years while I found a way to t…
> burnout that I later found out was in reality ME/CFS In my experience, burnout is really just a subconscious realization that what you're doing is just not worth doing , even for large amounts of money, and it manifests itself in fatigue or pain, because your mind is trying to stop you.
I was really pissed off, for a while, but these days, I have zero desire to return to the Rodent Rally. I have been talking with a friend about a possible effort to create an altruistic organization. I have a couple of bored, rich, retired friends. May not go anywhere, but ya never know...
Re: Side projects I've built since 2009
#126Earlier quoted context omitted.
> burnout that I later found out was in reality ME/CFS In my experience, burnout is really just a subconscious realization that what you're doing is just not worth doing , even for large amounts of money, and it manifests itself in fatigue or pain, because your mind is trying to stop you.
100% not true in my case and probably not true in the generally case, it’s a common misattribution. The cause of mine is hEDS which has ME/CFS as a comorbidity. I’ve done a WGS and found that I have 2 TNXB SNPs. By my math a lot of ‘burnout’ especially in tech is related to TNXB or CYP21A2 SNPs. The treatments that I take specifically targets IL-1B cytokines that are linked to brain fog. I was able to predict that I…
Re: Side projects I've built since 2009
#127Earlier quoted context omitted.
I'm going through a similar investigation. EDS + ME/CFS are the main suspects. Could live with the symptoms for very long, but they got too severe after covid (otherwise I would probably still be living with them). Is the treatment working out well for you?
I’m pretty much back to 100% I just get the occasional slump but I can’t be sure that isn’t from working too hard. For the IL-1B I take high doses of D3, TUDCA, and DIM. For the dysautonomia aspect I take Low Dose Naltrexone, a lower dose of modafinil in the morning and amitryptiline at night. I prefer weaker psychopharmacology ligands as it’s preferable to work with the natural rhythms of the body instead of fightin…
> which seems to have some weird comorbidities
I'm a bit shocked by your list of comorbidities. Not only yours, but also the one you linked to. MCAS is currently among my most pressing concerns, although it seems to be getting under control with H1 and H2 antihistamines + cromoglycate. An anti inflammatory diet also helps, even though I'm struggling to stay completely away from sugar. The psychiatric part calls my attention. I also present some traits of ADHD and ASD, although not enough to complete a diagnosis. Twenty years ago I joined mensa at the 99th percentile, but I do believe my IQ has decreased significantly since then. I can't even remember the last time I had, in my adulthood, my mind as functional as I used to have in my teenagehood, even before covid and the aggravation of the symptoms.
Out of your list, the only item I couldn't relate with were the medications working less than expected. In my case, I usually have stronger effects, both therapeutic and side ones. That happens with vaccines too. However, last weekend I took one for Influenza and the side effects were barely noticeable for the first time in my adult life -- I hope that's a result of the MCAS treatment.
Re: Side projects I've built since 2009
#128Earlier quoted context omitted.
That’s the first thing I thought about too. OP how do you sell your side projects? Does people just reach out or are you actively looking for people interested in buying?
I think "sold" probably doesn't mean what you think it means here. Have you looked at the projects? Nearly all of them are just statics lists of things. Like "a list of all country flags" or "a list of modern inventions" Maybe it was some SEO related sale with the domain and bit of ad revenue that someone bought for $100, which probably isn't the definition of selling a side project that most users on HN have. In fac…
Re: Side projects I've built since 2009
#129Earlier quoted context omitted.
I’m pretty much back to 100% I just get the occasional slump but I can’t be sure that isn’t from working too hard. For the IL-1B I take high doses of D3, TUDCA, and DIM. For the dysautonomia aspect I take Low Dose Naltrexone, a lower dose of modafinil in the morning and amitryptiline at night. I prefer weaker psychopharmacology ligands as it’s preferable to work with the natural rhythms of the body instead of fightin…
Glad to hear you are well. Also because that gives me some more hope. > which seems to have some weird comorbidities I'm a bit shocked by your list of comorbidities. Not only yours, but also the one you linked to. MCAS is currently among my most pressing concerns, although it seems to be getting under control with H1 and H2 antihistamines + cromoglycate. An anti inflammatory diet also helps, even though I'm strugglin…
It certainly sounds like a TNXB subtype of hEDS, this is an unofficial subtype, I read about the theory here on HN many years ago and ran with it. With an IQ that high I would take a guess that you have 2 TNXB SNPs. I'm happy to share more details on what has been figured out about these specific genes, I'll add an email address to my account.
I don't think the IQ points have been lost forever, I think I've recovered to my peak and possibly surpassed it with carful management of the meds. I think the general case of child prodigies burning out is simply a case of them not being able to get effective treatment and not an unavoidable innate quality.
Sugar is is still a tough one for me, it tends to give me headaches rather quickly which does make it easier to avoid it, but the desire for candy is always there.
Re: Side projects I've built since 2009
#130Earlier quoted context omitted.
The psychosomatic view of ME/CFS was and in many places remains the expert opinion and one that I agree is misleading and damaging. It was pushed by a highly influential team of British psychiatrists. Many countries still prescribe exercise as the official treatment which is horrific, especially when MAID is given as an alternative. I’m understand of skepticism. My position is that of a subset of the patient communit…
Didn't they do the same with Lyme Disease? Lotta folks died, because of that.
Medical history is a horror show. It's weird that we have absolutely fantastic sources of information and tooling with abundant genome sequences and computers to process them and still medicine is very much prestige driven where dominant experts can hold back competing research for generations. I think patients will increasingly do an end run around them with more patient community sharing.
I do think ozempic will turn out to be a wonder drug not just for weight but also for auto-immune. And then consider - how much of mental illnesses is actually an expression of an auto-immune disorder. I think we're going to find out, and I expect we will look back on how badly people with mental illnesses were treated like we now look back on those who were lobotomized.