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Viagra improves brain blood flow and could help to prevent dementia

ox.ac.uk

121–130 of 289 posts

Re: Viagra improves brain blood flow and could help to prevent dementia

#121
post #8
post #4

Earlier quoted context omitted.

You take it for this purpose or why?

Looks like 5mg viagra is 10%-20% of the minimum recommended dose for viagra's original purpose

GP is talking about cialis (tadalafil), a completely different drug. It is dosed differently from viagra (sildenafil).

Re: Viagra improves brain blood flow and could help to prevent dementia

#122
post #33
post #26

> The OxHARP trial was a meticulously designed double-blind, placebo-controlled study involving 75 participants who had experienced a minor stroke and showed signs of mild to moderate small vessel disease. Each participant received sildenafil, a placebo, and cilostazol (a similar drug) over three-week periods in a randomised order. I feel like dudes will know if they got Viagra or not? It doesn't seem like cilostazol…

Viagra doesn't "make" you hard, you still need sexual stimulus. I've taken it and then the sexual opportunity fell through, so I went back to coding or whatever, and I didn't notice anything different.

Maybe that's just java language, have you tried with other ones?

Re: Viagra improves brain blood flow and could help to prevent dementia

#123

I always wonder if there is a circular logic flaw in survey studies of recreation and dementia: could it be that the folks who are chasing Viagra or running marathons don't get dementia, because the ones with dementia don't pursue these activities?

This isn't a survey; it's an RCT.

Re: Viagra improves brain blood flow and could help to prevent dementia

#124

First NIH said it does: https://www.nih.gov/news-events/nih-research-matters/viagra-... Then it doesn't: https://www.nih.gov/news-events/news-releases/nih-dream-stud... Then it does: https://www.ox.ac.uk/news/2024-06-07-sildenafil-viagra-impro... Who knows what to believe.

Maybe these studies are particularly hard

It’s hard science. I take viagra every day and have only become moderately demented, so obviously it’s working.

Re: Viagra improves brain blood flow and could help to prevent dementia

#126

First NIH said it does: https://www.nih.gov/news-events/nih-research-matters/viagra-... Then it doesn't: https://www.nih.gov/news-events/news-releases/nih-dream-stud... Then it does: https://www.ox.ac.uk/news/2024-06-07-sildenafil-viagra-impro... Who knows what to believe.

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Re: Viagra improves brain blood flow and could help to prevent dementia

#127

Well. too sad I can't take it. It gives me terrible heartburn (an acute stomach pain, not a heart related condition) that only partially responds to anti-acids such as Alka Seltzer. Also, extremelly stuffy nose, to the point where basically I need to breath by the mouth. And the red eyes, eyes as red as if had just smoke the biggest and strongest joint ever. Yes, I tried to use it recreationally a few times. It is no…

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Re: Viagra improves brain blood flow and could help to prevent dementia

#128

Well. too sad I can't take it. It gives me terrible heartburn (an acute stomach pain, not a heart related condition) that only partially responds to anti-acids such as Alka Seltzer. Also, extremelly stuffy nose, to the point where basically I need to breath by the mouth. And the red eyes, eyes as red as if had just smoke the biggest and strongest joint ever. Yes, I tried to use it recreationally a few times. It is no…

It sounds like you have at least a small allergy to something in the drug. The stuffy nose is something I get when I take trazodone.

Re: Viagra improves brain blood flow and could help to prevent dementia

#129

Earlier quoted context omitted.

They certainly are hard, because dementia is something that develops over years if not decades. Anytime it takes that long to do a single iteration of your experiment, it's hard!

Does it need to be, though? You can survey healthy but senior populations about their habits, and then over the following years track what happens. If medical records were public, the answers could even be in those for any medicines that are prescription based. You could then make statements like "A% of patients who took drug B within C years did/didn't develop disease D".

That's not a randomized controlled trial though. You might find a correlation, but you couldn't actually establish causation, or eliminate hidden variables.

Re: Viagra improves brain blood flow and could help to prevent dementia

#130

Well. too sad I can't take it. It gives me terrible heartburn (an acute stomach pain, not a heart related condition) that only partially responds to anti-acids such as Alka Seltzer. Also, extremelly stuffy nose, to the point where basically I need to breath by the mouth. And the red eyes, eyes as red as if had just smoke the biggest and strongest joint ever. Yes, I tried to use it recreationally a few times. It is no…

Yeah I occasionally take it or tadalafil for BPH/prostatitis because they have less side effects than alpha blockers. I've got GERD and a hiatal hernia and, man, it really fires it up. Chewing gum sort of helps. I also only take half of a 25mg. I'll sometimes get the stuffy nose and rarely a headache but the stomach issues almost prevent me from using it. I've sort of grown used to tolerating extreme stomach pain though, so I still use it if I really need it.
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