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Taurine deficiency as a driver of aging

science.org

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Re: Taurine deficiency as a driver of aging

#121

Post by etiam »

heisenbit wrote: post #94
Fauntleroy wrote: post #20

Earlier quoted context omitted.

I have extremely strong anecdotal evidence that sucralose is toxic to my gut fauna. Two years of suffering are enough to convince me, but I'm hopeful to see the research that confirms it sooner than later.

This is actually a good point: The fact that it does not get metabolized by the body does not mean it does not get metabolized by some valuable bacterial symbionts.

Another good point was, the fact that it doesn't get metabolized (much) before excretion does not mean it does not interfere in destructive ways with valuable physiological processes on the way:

https://www.science.org/content/blog-post/trouble-erythritol

Re: Taurine deficiency as a driver of aging

#123

Post by detrites »

Blackthorn wrote: post #119
detrites wrote: post #115

Earlier quoted context omitted.

2-3 generations. Historically demonstrable as a metric to be sure about the ill effects of a new substance/tech. History is littered with examples of consumers & industry placing convenience & profits ahead of what's sensible to these ends. Eg, X-rays - 60 years from invention, popularity, child use, "crazy" people claiming they're bad, to suspicion they might be, conservative study, realising they're screwed, all ki…

> I mean, why are people even considering artificial sweeteners? Isn't it only because it's taken us all several decades to realise refined sugar is fucked after initially thinking it was great if not at least "safe"? Can't speak for anyone else obviously, I use sucralose to sweeten plain nonfat greek yogurt for breakfast. It tastes like churned asshole without it, but it's otherwise a great food with everything I ne…

Agree on the Greek yoghurt taste. I'd sweeten it with banana, as it can mix nice without much effort and is also packed with nutrients along with only a tiny bit lethal radiation. Calories I've no idea about though.

Re: Taurine deficiency as a driver of aging

#124

Post by [deleted] »

Blackthorn wrote: post #4
Grazester wrote: post #3

Earlier quoted context omitted.

Was actually needing some caffeine to up me toda. I debated having a sugar free Red Bull but even the sugar free ones are not great for you due to the sucralose

I know I won't change anyone's already set opinions here, but for anyone reading this and not sure what is being discussed: there's absolutely nothing wrong with consuming sucralose.

[deleted]

Re: Taurine deficiency as a driver of aging

#125

Post by friend_and_foe »

alexfromapex wrote: post #18

Turns out Monsters are pretty healthy for you except for all the sugar.

Yup. I used to be a heavy monster drinker, and I quit because that much sugar a day will kill you eventually.Ia drink a cup of coffee every day now, but I do sip an energy drink when I go on a multi hour drive, and I've found the alertness is unmatched by coffee. So I started adding taurine to my coffee, it works almost as well, good mood lift.

Re: Taurine deficiency as a driver of aging

#126

Post by xcv123 »

Blackthorn wrote: post #118
xcv123 wrote: post #114

Earlier quoted context omitted.

You wrote > there's absolutely nothing wrong with consuming sucralose Well, there are studies showing that there is something wrong with consuming sucralose. I posted a link to such a study. That contradicts your statement.

You actually posted a link to a news article about a study, not a link to a study. And no, it doesn't contradict my statement that there's nothing wrong with consuming sucralose. It by itself is a piece of evidence, and doesn't by itself override decades of evidence.

The article contains direct links to studies

https://www.tandfonline.com/doi/full/10.1080/10937404.2023.2...

https://www.bmj.com/content/378/bmj-2022-071204

https://www.frontiersin.org/articles/10.3389/fnut.2022.84839...

https://www.mdpi.com/2076-2607/10/2/434

This obviously logically contradicts your statement.

Your sophistry is incredible. Let's see how you bullshit your way out of this one.

Re: Taurine deficiency as a driver of aging

#127

Post by ThrowawayR2 »

opisthenar84 wrote: post #5

So... drink more Red Bull?

More like eat more sashimi (which is uncooked by definition) or sushi that contains sashimi since uncooked fish meat contains a fair bit of taurine. Carpaccio would be a good option as well. If my budget supported it, that's a dietary change I'd be more than happy to make.

Re: Taurine deficiency as a driver of aging

#128

Post by fnordpiglet »

DoreenMichele wrote: post #24

Taurine is an amino acid, aka a building block of protein. It's found in abundance in meat and seafood. (I had trouble parsing the title of this piece. Insert joke here about how I don't need to read this article because I no longer own a car nor have a driver's license.)

Taurine does not contribute to protein structure.

Taurine helps regulate the levels of water and minerals in the blood, contributing to overall fluid balance and proper functioning of the muscles and nerves.

Also it acts as a neurotransmitter in the brain.

Taurine is found in high amounts in the eye and it's thought to protect against retinal degeneration.

Finally Taurine is used in the formation of bile salts.

But, unlike most amino acids it’s not used in protein synthesis.

Re: Taurine deficiency as a driver of aging

#129

Post by majkinetor »

gattilorenz wrote: post #89
isk517 wrote: post #71

Earlier quoted context omitted.

You probably can live longer if you stick with coffee (black), berries (minus the food you put the berries on top of), dark chocolate (unsweetened), and wine (in strict moderation).

Alcohol is a carcinogen, so if you’re optimizing for “living longer” you should take exactly 0 mL a day. If you’re optimizing for living happier, on the other hand…

There is no such thing as 0 tollerance. Don't believe the anti-alcohol hype. There is such thing as hormesis, for basically any poison.

Re: Taurine deficiency as a driver of aging

#130

Post by Turing_Machine »

A_D_E_P_T wrote: post #66
rale00 wrote: post #26

Earlier quoted context omitted.

You don't directly convert dosage across species like that. The dosage they tested on monkeys was 250mg/kg, and the human equivalent would be less than that.

The basic formula from mouse to human is (X mg * (3/37)) = human equivalent dose in mg/kg. In this case (1000mg * 3/37)) comes out to 81mg/kg. So, if you weigh 80kg, it comes out to 6.48 grams per day. That's a lot of taurine, but not really a crazy amount. Easy enough to consume.

I see that Amazon sells 1 gram capsules of taurine (several vendors). So, yeah, not too difficult to consume. One brand I saw is about $0.08/gram, so it wouldn't be overly financially burdensome, either.
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