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Widely used chemical strongly linked to Parkinson’s disease

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Re: Widely used chemical strongly linked to Parkinson’s disease

#121

Post by TedDoesntTalk »

anaisbetts wrote: post #24

Widely used chemical *(that was generally phased out in the 70s) linked to Parkinson's. Still important, but you don't need to start searching product labels in 2023 for it.

TCE is present at Lowry in Denver, an old air force base that is now a huge development of multi-million dollar homes and townhomes.

This article is from 2000, before the housing development began. People knew TCE was there but the housing development happened anyway

https://extras.denverpost.com/news/news1126.htm

It’s also at Stapleton, another huge residential area, and previously Denver’s primary airport:

“At the former Stapleton Airport, which is also being redeveloped, the TCE is 35 to 40 feet deep, according to Tom Gleason, spokesman for Forest City Stapleton Inc., the private developer overseeing the building.

He said it won't have any effect on the redevelopment, which will include homes and commercial areas.”

Indeed, it didn’t. The redevelopment happened anyway. And now I’d guess it’s in the air, water, and of course the soil.

Re: Widely used chemical strongly linked to Parkinson’s disease

#122

Post by kadoban »

bumby wrote: post #108
kadoban wrote: post #74

Earlier quoted context omitted.

Caffeine pills it's a bit easy to unconciously take too much and get all jittery, and it's not really spread out enough. Optimal consumption of caffeine seems to be a decent-sized initial intake, then smaller doses over time to maintain (eg take a few more sips). There's no good way to do that with pills.

How confident are you in the dosage in each cup of coffee?

Fairly confident, within 2x or so.

But it barely matters, it's not like I'd inject the whole cup into my veins and then see what happens.

If the caffeine was too high (within reasonable variations), you'd notice and slow down consumption before it mattered. If it's too low, you can just drink more. You can do it by feel, which is I think what just about everyone does.

Some of it might be placebo, but if so I'm not sure it changes anything really, since the goal is just to feel a certain way anyway.

Re: Widely used chemical strongly linked to Parkinson’s disease

#123

Post by YeGoblynQueenne »

anaisbetts wrote: post #24

Widely used chemical *(that was generally phased out in the 70s) linked to Parkinson's. Still important, but you don't need to start searching product labels in 2023 for it.

This paragraph from the article explains the significance of the reported result (and the motivation behind the study):

>> About 90% of Parkinson’s cases can’t be explained by genetics, but there have been hints that exposure to TCE may trigger it. The new study, led by researchers at the University of California, San Francisco (UCSF), represents by far the strongest environmental link between TCE and the disease. Until now, the entire epidemiological literature included fewer than 20 people who developed Parkinson’s after TCE exposure.

That is to say, the relation between TCE and Parkinsons had, until now, no strong evidence to support it. It seems (not sure, not my field) that now it does.

Also note, from the article:

>> “Alarmingly, TCE vapor intrusion is widespread today and ranges from an elementary school situated on top of a former chemical facility in Shanghai, China, to multimillion-dollar homes built on a previous aerospace plant in Newport Beach, California,” the authors of an accompanying editorial in JAMA Neurology write.

Re: Widely used chemical strongly linked to Parkinson’s disease

#124

Post by alistairSH »

wouldbecouldbe wrote: post #61
pmoriarty wrote: post #10

"After adjusting for differences in age, sex, race, and ethnicity, the scientists found veterans from Camp Lejeune had a 70% higher rate of Parkinson’s disease than the Camp Pendleton group." Why didn't they adjust for socioeconomic status? Wealthier people tend to be able to afford better medical care, live in healthier environments, eat healthier foods, etc. These could all be confounding factors, and a study like…

Yeah and as well as soldiers being exposed to different chemicals & other circumstances then the general population. Would be great if they would compare it with other army base around the same time.

They did... the control was Camp Pendleton.

Re: Widely used chemical strongly linked to Parkinson’s disease

#126

Post by alistairSH »

notakio wrote: post #46
AdamN wrote: post #15

Earlier quoted context omitted.

Alot of socioeconomic factors are baked into the above co-morbidities but anyway, is there a reason to think that veterans of two different marine camps have significantly different socioeconomic profiles from eachother?

In this case (Lejeune vs Pendleton), there would likely not be a substantial socioeconomic difference between the collective backgrounds of Marines who did basic training at either one. But comparing either camp to OCS at Quantico would, in fact, show a pretty stark delineation between the socioeconomic backgrounds.

They looked at officer vs enlisted, which would cover any socioeconomic difference between basic vs OCS, no?

Re: Widely used chemical strongly linked to Parkinson’s disease

#127

Post by throwaway2037 »

horeszko wrote: post #73

>"But in the 20th century, TCE was used for many purposes, including making decaffeinated coffee" ... This is exactly the reason I never touched decaf coffee until I found Swiss water process (SWP) decaf. It never made sense to me to use hydrocarbon solvents in a food application

Thank you to share abuot SWP. I didn't know about it. This page explains how it works: https://www.haymancoffee.com/blogs/coffee-blog/how-is-coffee...

At this point, it looks like the solvent thing is probably overstated (in highly developed/regulated countries)). This page has info about the history of different solvents: https://www.coffeereview.com/coffee-reference/coffee-categor...

Re: Widely used chemical strongly linked to Parkinson’s disease

#128

Post by Hnrobert42 »

dist-epoch wrote: post #35
eimrine wrote: post #3

When you drink your coffee without caffeine in your 30 for escaping a harm from caffeine, but end up with Parkinson in your 60+.

Why would you drink coffee if not for the caffeine. It's not exactly the most delicious drink.

I drink decaf, and I mostly agree with you.

I drink it because when I need caffeine, decaf has enough for me. When younger, I drank it to fit in.

With enough sugar and milk, it tastes great, but so would anything. I am sure high-end coffee is great, but it’s never worth the effort to me, so I don’t know about that.

Re: Widely used chemical strongly linked to Parkinson’s disease

#129

Post by robertlagrant »

rob74 wrote: post #32
swarnie wrote: post #18

Earlier quoted context omitted.

What is Tricholoroethylene? "A widely used chemical" ....

"Widely used chemical Tricholoroethylene strongly linked to Parkinson"

Renowned author Meredith Wadman

Re: Widely used chemical strongly linked to Parkinson’s disease

#130

Post by rdl »

swarnie wrote: post #58
croes wrote: post #49

Earlier quoted context omitted.

Imagine this headline A widely known basketball team wins NBA finals Clickbait?

Depends on the audience i guess, im not sure i can name a basketball team. Does the average reader of science.org know what trichloroethylene is without a prompt?

I know of it as "dry cleaning chemical and why you don't want to buy a building which used to contain a dry cleaning shop with on-premises processing".
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