There are techniques I'd been using for a long time, complicated little tasks with, on the face of it, simple results, that I wasn't able to reproduce in AD without a lot of thinking and farting around. For better or worse, this pushed me to change things up and explore other methods, and now I've learnt how to achieve things with programming, whether that's Processing or little things for Blender.
I know people operating businesses who've just stuck with an old computer running an old non-subscription version of the Adobe software they depend on. They don't really need anything from modern versions (some have been doing things since the '70s, adding computers to the mix in the '90s, and their techniques have not really changed all that much), and its Affinity kinda-equivalent is missing some little thing.
For me, just looking at the changes, V2 isn't terribly compelling. There are things I was doing ages ago in Illustrator that don't seem to be in Designer v2, like vector pattern swatches. Once you really get going with it, the absence of features or rough edges (see post in this thread about dashed borders) will leave you frustrated.
All that said, good on them for creating this affordable software, with no subscription.