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Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

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Re: Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

#122

Earlier quoted context omitted.

You're overly confident in your tone and thin on details (and a written link goes further than a YouTube reference). How in the world is a remaining hunter gatherer population in 2022 a proxy for what happened tens of thousands of years ago. That's an assumption you're expected to justify, first off. Secondly, how is food abundance being modern a 'brainletism' or whatever you're enjoying repeating as a sort of provoc…

> and a written link goes further than a YouTube reference That's an interview with Herman Pontzer, PhD, the lead author of the most import papers published to date studying the energy expenditure of the Hadza of Tanzania, one of the few remaining hunter-gather populations. By all means, keep believing that your ancestors subsisted off of 100% Woolly Mammoth meat in between days of starvation, if it makes you happy.

No post body was provided.

Re: Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

#123

Earlier quoted context omitted.

I know this feeling well. This is a false sense of sharpness caused by undereating. You dont feel hungry or tired, just energized, light and strong. I say false sense of sharpness, because you're actually not that alert. Yes, you can push yourself more, but your brain is in flight/fright mode and not thinking rationally.

Are you sure that that is all there is? May I point to one paper of many that show proinflammatory cytokines to be reduced due to intermittent fasting? “Under controlled conditions, [diurnal intermittent fasting] led to significantly decreased plasma levels of cytokines (IL-1β, IL-6, and IL-8), particularly IL-1β and IL-6 across 24 h.” – The effects of diurnal intermittent fasting on proinflammatory cytokine levels w…

We tend to eat up mechanistic reports that make us feel good about our preferred lifestyle, but in this topic you’d want to find experiments that increase alertness during IF (something that actually confirms an endpoint). Maybe they exist.

A classic example is the “antinutrients in plants” mechanistic fad while plants in a diet actually increase all health outcomes when put to the test.

Exercise causes a huge inflammatory response too. Thankfully we know better than to stop the analysis there.

Re: Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

#124
post #71
post #68

Earlier quoted context omitted.

It's a beautiful thing that we can rebrand "hangry" as "warrior mode". I also noticed this and just came to the conclusion that having breakfast and being in a good mood ("off edge"/"relaxed"/"opposite of warrior mode") was more worth it.

I’m going to tell my wife I’m in “warrior mode” the next time I’m being a hangry jerk. I wonder how that will go.

Next time I skip a meal I’m going to say it’s my tribal warrior response when I feel like raiding the fridge.

Re: Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

#125
post #78
post #59

Earlier quoted context omitted.

No, all your eating happens in that 10 hour window. You fast for at least 14 hours per day. Easy enough if you eat an early dinner and don't snack after.

Is the position of that window relevant? So, I sleep 9h, which means, I'm awake 15h. If I don't eat 2,5h before and after sleeping, would this be enough?

> If I don't eat 2,5h before and after sleeping, would this be enough?

Some researchers think so, yes. I don't think anyone knows what is optimal. Research is ongoing.

Re: Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

#126
post #108

Earlier quoted context omitted.

What purpose does that last sentence serve?

Should I be more tactful towards dangerous health misinformation being spread here?

It actively thwarts that goal.

Re: Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

#127

Earlier quoted context omitted.

Are you sure that that is all there is? May I point to one paper of many that show proinflammatory cytokines to be reduced due to intermittent fasting? “Under controlled conditions, [diurnal intermittent fasting] led to significantly decreased plasma levels of cytokines (IL-1β, IL-6, and IL-8), particularly IL-1β and IL-6 across 24 h.” – The effects of diurnal intermittent fasting on proinflammatory cytokine levels w…

We tend to eat up mechanistic reports that make us feel good about our preferred lifestyle, but in this topic you’d want to find experiments that increase alertness during IF (something that actually confirms an endpoint). Maybe they exist. A classic example is the “antinutrients in plants” mechanistic fad while plants in a diet actually increase all health outcomes when put to the test. Exercise causes a huge inflam…

The exercise inflammatory/antiinflammatory control loop is indeed wildly interesting! As are the nuances of how the interleukins work.

I deeply encourage people to read the science. And indeed all of it.

As you said: Maybe they exist. They probably do – if the substrate of under-funding things has allowed them to come into existence. There are studies that show general health benefits from intermittent fasting as I recall.

It’s also worth paying attention to one’s experience of the world, and to not discredit it. There’s a distinction between following a fad, preferring a lifestyle, wanting to feel good about it – in a social sense I guess? …versus, say, noticing a sense of clarity whole watching one’s bloodwork results improve.

Read papers. Mostly science. Not too carefully.

Mechanistic ones too. Mechanistic ones too! From personal experience, I ask you to believe me when I give insulin glargine as a clear example of the molecular biology of something clearly showing that a certain medicine is literally dangerous. The zoomed-out general health studies smooth over the substance’s obvious capacity to abruptly flow out of bolus sites and dump 24 hours’ worth of insulin into the bloodstream. It’s obvious from the molecular biology and the anecdotes of horrible blood sugar crashes and people dying in their sleep. Please don’t take too much salt with the mechanistic studies. It’s mechanics all the way down.

Re: Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

#128

Really enjoying IF and it's had enormous benefits for me. The doc basically said my latest bloods are outstanding, way, way down from the serious telling-off I got 6 months ago. I'm not using someone else's schedule, just listening to my body and pushing boundaries as hard as my fitness will allow. But there are mental "downsides" to reckon with. It's not grumpiness, but rather a "predatory" state. Not quite aggressi…

> The doc basically said my latest bloods are outstanding What was the change in blood reports? I am surprised somone can simply reverse their 'serious' metabolic disease state in mere 6 months. Then what would be the point of living a healthy lifestyle everyday if you can simply 'get healthy' in a matter of months when you need it. I've wondered about this for a while. My friends don't give a shit about health and b…

Your body really doesn't want to be in some states (because you'll die) so certain markers/metabolic disease states like NAFLD and pre-T2D MetS will lower dramatically soon after the insult (chronic overfeeding) is stopped. RCTs have shown dramatic improvements in as little as a week or two. In my case, both my elevated AST and TG numbers halved a month into making significant lifestyle changes and almost all my bloodwork continued to improve dramatically into my next labs at 9mo and 1y.

That isn't to say there isn't accrued/long term damage, I think most people going through this sort of change will tell you that they are still dealing w/ health issues long term. I've notice that years after my initial interventions, my body still seems much more predisposed to weight gain for example - but trust me though, not feeling like crap is it's own reward. You can basically get used to anything and you don't really realize just how bad you were feeling (slowly getting worse over the course of a decade or so for me) until you turn it around.

Re: Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

#129

Earlier quoted context omitted.

I know this feeling well. This is a false sense of sharpness caused by undereating. You dont feel hungry or tired, just energized, light and strong. I say false sense of sharpness, because you're actually not that alert. Yes, you can push yourself more, but your brain is in flight/fright mode and not thinking rationally.

[Citation required]

[anecdote implied]

Re: Study: Time-Restricted Eating Improves Cardiovascular Health for Firefighters

#130

Earlier quoted context omitted.

>Then what would be the point of living a healthy lifestyle everyday if you can simply 'get healthy' in a matter of months when you need it. Because the labs are just indicators of whether or not damage is being done. If you have high LDL for example, disease state is correlated to how long, and how high LDL levels have been. (The evidence for that is robust.) So for example, while you can improve those levels in 6 m…

> that doesn't mean you weren't racking up damage for the previous 10 years. > and risk of adverse events are correlated to how high and how long levels were maintained. Is there a way to measure this though. How can I tell what my current level of damage is. GP got the usual indicators into shape. Is all the 'racking up damage' reversed in OPs case ?

>Is there a way to measure this though. How can I tell what my current level of damage is.

It's a cumulative thing. There are ways to ascertain the damage, but not through routine tests.

>GP got the usual indicators into shape. Is all the 'racking up damage' reversed in OPs case ?

Particularly in the case of cardiovascular damage like atherosclerosis and resulting kidney damage, narrowing arteries, etc, no it's not reversed.

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