WINNERS: Large corporations and financial institutions. They can afford the now-required overhead for all kinds of services, including transaction processing with fees and rewards, i.e., mining, and make a nice profit at high volumes. LOSERS: Smaller service providers. They cannot afford the now-required overhead because they don't have sufficient economies of scale.
LOSERS: Criminals who saw so much hope in trivially laundering their ill gotten gains now see that as slightly less likely.