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CDC Internal Delta Variant Presentation

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Re: CDC Internal Delta Variant Presentation

#121
post #117

If vaxxed people are still getting infected and transmitting Delta at similar rates as unvaxxed, then the reasons for getting vaxxed are: - lower your own chances of symptomatic disease, severe illness, hospitalization and death - and therefore, help keep the healthcare system from collapsing

They aren't though.

Re: CDC Internal Delta Variant Presentation

#122
post #109

Wow these slides are packed with information and accompanying citations - truly a great resource for anyone following the literature regarding COVID-19 and especially the variants of concern. I need more time to digest this presentation, but there are two important topics that I feel are missing or at least underrepresented: 1) The effectiveness of early outpatient treatment using a combination of existing medicines…

> The speed at which nAb resistance develops in the population increases substantially as the number of infected individuals increases, suggesting that complementary strategies to prevent SARS-CoV-2 transmission that exert specific pressure on other proteins (e.g., antiviral prophylactics) or that do not exert a specific selective pressure on the virus (e.g., high-efficiency air filtration, masking, ultraviolet air p…

That is one way to look at the situation, but it will be a long time before we can definitively say this was a major error relative to other recommendations and actions taken.

A broader perspective and perhaps a better takeaway is that to mitigate this pandemic it seems we - collectively as a society - need to focus on more sophisticated & multi-faceted strategies beyond the current mRNA vaccines, lock-downs, and masks.

Re: CDC Internal Delta Variant Presentation

#123
post #102

Delta is getting a crazy amount of press but for some reason most articles don’t show any of the articles stats. For instance rather than show cases or deaths, they show “percent of cases that are delta.” Here is the CDC chart showing cases and deaths by group. https://covid.cdc.gov/covid-data-tracker/#demographicsoverti... Cases are increasing but even case increase is a tiny blip compared to winter. Cases have alwa…

> Cases are increasing but even case increase is a tiny blip compared to winter. If you look at the US as a whole cases are not are still well below the worst daily averages of last Christmas, but blip is a much stronger word than I'd use when the trend line is pointed up with no obvious end in sight. Drill down on the individual states with the most issues and you'll see that places like Louisiana are basically at t…

True cases are equal in some areas like Louisiana and Florida. Florida is completely open with the worst possible scenario of practically no masks, low vaccine rates, and enormous crowds but has only 1.4 weekly deaths per 100,000, low but above the national average of .5 weekly deaths per 100,000. Compare this with deaths from all other causes which average about 16 weekly deaths per 100,000. So yea we have a problem but at the current rate you are more likely to die from a stroke than COVID. You are about half as likely to die by suicide. You are about 6 times as likely to die from heart disease than COVID. I’m just saying there are other things to be afraid of and focus on than the pandemic.

Re: CDC Internal Delta Variant Presentation

#124

Earlier quoted context omitted.

Google for 'gun violence epidemic' and you will find lots of high profile results pretending it is.

I mean it is, it’s not a contagious pathogen. Unless you think it’s normal that American society has more mass shootings than I can keep track of in recent memory then i’d call it an epidemic. People walking into churches, schools, concerts, etc… and indiscriminately killing people is a deep sickness in American society.

Sometimes I forget I need to explain humor or irony and I am not even the native English speaker. But I accept this as my fault.

Re: CDC Internal Delta Variant Presentation

#125
post #117

If vaxxed people are still getting infected and transmitting Delta at similar rates as unvaxxed, then the reasons for getting vaxxed are: - lower your own chances of symptomatic disease, severe illness, hospitalization and death - and therefore, help keep the healthcare system from collapsing

They aren't though.

[deleted]

Re: CDC Internal Delta Variant Presentation

#126
post #117

If vaxxed people are still getting infected and transmitting Delta at similar rates as unvaxxed, then the reasons for getting vaxxed are: - lower your own chances of symptomatic disease, severe illness, hospitalization and death - and therefore, help keep the healthcare system from collapsing

They aren't though.

Headline on Slide 17 in the deck:

Delta variant vaccine breakthrough cases may be as transmissible as unvaccinated case

Re: CDC Internal Delta Variant Presentation

#127
post #126

Earlier quoted context omitted.

They aren't though.

Headline on Slide 17 in the deck: Delta variant vaccine breakthrough cases may be as transmissible as unvaccinated case

It does not confirm your point. It says roughly "if a vaxxed and unvaxxed people are equally sick (e.g. same strength of symptoms), they transmit equally". However, vaxxed people get sick ~20x less, so they transmit ~20x less overall. (20x is a bad estimate here, taken from efficiency against hospitalizations)

Re: CDC Internal Delta Variant Presentation

#128
post #109

Earlier quoted context omitted.

> The speed at which nAb resistance develops in the population increases substantially as the number of infected individuals increases, suggesting that complementary strategies to prevent SARS-CoV-2 transmission that exert specific pressure on other proteins (e.g., antiviral prophylactics) or that do not exert a specific selective pressure on the virus (e.g., high-efficiency air filtration, masking, ultraviolet air p…

That is one way to look at the situation, but it will be a long time before we can definitively say this was a major error relative to other recommendations and actions taken. A broader perspective and perhaps a better takeaway is that to mitigate this pandemic it seems we - collectively as a society - need to focus on more sophisticated & multi-faceted strategies beyond the current mRNA vaccines, lock-downs, and mas…

B E T T E R I N D O O R V E N T I L A T I O N

Re: CDC Internal Delta Variant Presentation

#129

Earlier quoted context omitted.

Yeah, this is not a slide of recommendations; that’s describing the model assumptions illustrated by the charts. Essentially, it says “these charts don’t include modeling the impact of any additional mitigations aside from masking”; these charts show that we must enforce universal masking immediately at minimum. On the last slide, “Next Steps for CDC”, they explicitly list: > ▪ Prevention > – Consider vaccine mandate…

I feel like we are in complete agreement on the facts, but are somehow coming to opposite conclusions. Slide 21, bold red text, surrounded by a red box: "Given higher transmissibility and current vaccine coverage, universal masking is essential to reduce transmission of the Delta variant" If this is supposed to imply that restaurants need to be closed, I feel like it should instead actually explicitly say that, becau…

I think you've misunderstood the slide. It says: If we do no other mitigations other than wearing masks (3 variants in the graph), this is what happens.

If additional stuff is done, then the risk goes down. It does not say how much, maybe a little, maybe a lot. But such other mitigations are unlikely to happen if the easiest, most effective and most accepted way, wearing masks, is not enforced already. That's why it makes sense to look at the case of masks-only.

Re: CDC Internal Delta Variant Presentation

#130
post #126

Earlier quoted context omitted.

Headline on Slide 17 in the deck: Delta variant vaccine breakthrough cases may be as transmissible as unvaccinated case

It does not confirm your point. It says roughly "if a vaxxed and unvaxxed people are equally sick (e.g. same strength of symptoms), they transmit equally". However, vaxxed people get sick ~20x less, so they transmit ~20x less overall. (20x is a bad estimate here, taken from efficiency against hospitalizations)

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