I think the #1 reason blockchain doesn't work is very simple - the technology is broken beyond fixability. This article is two years old, but the same variations of these excuses always come up when the crypto ideologues are grilled on why their utopiaic vision hasn't come about, for all of blockchain's existence. Blockchain is awful for most things compared to a centralized or distributed database: it is inefficient…
This decision flow chart is Figure 6 of NISTIR 8202, "Blockchain Technology Overview":
* https://csrc.nist.gov/publications/detail/nistir/8202/final
See page 53 of the PDF ("42" at the bottom of page, 'physically').
If you need a handy guide to give to someone to explain blockchain (though not crypto currencies), it's hard to go wrong with send people this link.
For a more finance-y, the CFA Institute has a useful white paper:
* https://www.cfainstitute.org/en/research/foundation/2021/cry...