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Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

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Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#121

Post by roel_v »

toshk wrote: post #116
roel_v wrote: post #94

Earlier quoted context omitted.

I always see Americans (apologies for making assumptions if you're not) throw around blood testing like it's something trivial and casually done. Here in the Netherlands, it takes a real medical indication and some pushing of a doctor to get any testing done. Alternatively, you use a private testing company that costs 200 to 400 euros for a comprehensive screening. Question to the public in various countries - how ea…

You can get an extensive screening for around 120 here in Amsterdam. Probably more expensive if I go through official doctor and have to pay it with eigen risico (first few 100 euros of healthcare you pay yourself).

Where is that? I only looked online, I haven't found anything online that cheap that includes vitamin/mineral levels + hormones.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#122

Post by cassepipe »

ve55 wrote: post #5

It's worth noting that vitamin D has a lot of high-confidence but low-effect results going for it, including a lot of strong meta-analysis over many health outcomes. What I mean by this is that it usually seems to conclusively either do something beneficial, but minor, almost nothing in the case of many studies, and in the case of some others, something very beneficial (as we've seen a few of in relation to covid rec…

"The non-financial costs such as side effects or potential adverse effects are practically non-existent as well."

This not accurate. I remember that there was an article on the front page of Hacker News an article that explain that Vitamin D is actually a hormone and telling the story of woman that had been prescribed high level of supplementation that could not talk anymore. It had something to do with her calcium intake regulated by that hormone. Luckily she was so distressed she stopped taking the supplementation but still it took her six months to get back to to talking normally and a normal hormone concentration level.

EDIT : I found the article : https://news.ycombinator.com/item?id=24261948

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#123

Post by gnrlst »

roel_v wrote: post #94
monetus wrote: post #34

Earlier quoted context omitted.

For reference: The level of toxicity listed in your link is 60,000IU per day. Fauci said he takes 10,000IU per day. The bottle I purchased recommends 2,000IU per day. Get your blood work done people.

I always see Americans (apologies for making assumptions if you're not) throw around blood testing like it's something trivial and casually done. Here in the Netherlands, it takes a real medical indication and some pushing of a doctor to get any testing done. Alternatively, you use a private testing company that costs 200 to 400 euros for a comprehensive screening. Question to the public in various countries - how ea…

Italy here: just went to my doctor and said "hey, i should get a blood test since I haven't had one in a couple years"...my doctor said "yes, please do" -> got a prescription and went to the hospital. I think I paid something like 20 euros to do it at a private hospital that is affiliated with the state health program, after I added urine testing and a couple of additional tests to the bloodwork.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#124

Post by fujiters »

ben_w wrote: post #108
elric wrote: post #93

Earlier quoted context omitted.

The way I understand it is that drinks fortified with Vit D are nearly always fortified with D2, whereas the consensus seems to be that D3 is the way to go. Not sure whether that's because D3 is less stable in drinks, or maybe there's another reason to prefer D2 there?

According to this article D3 is never vegan: https://www.healthline.com/nutrition/vitamin-d2-vs-d3#TOC_TI... I believe “being vegan” is the point of most milk substitutes.

Fair point, but D3 can also be derived from lichen, which is vegan.

https://www.vegansociety.com/resources/nutrition-and-health/...

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#125

Post by tgsovlerkhgsel »

monetus wrote: post #34
throwaway5752 wrote: post #23

Earlier quoted context omitted.

It is fat soluble. You can develop toxicity, and the effects are not trivial: https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-h... It seems based on casual reading of research that more people are deficient than not and dosing to toxic levels is unlikely. But it's not a bad idea to do this under the care of a doctor.

For reference: The level of toxicity listed in your link is 60,000IU per day. Fauci said he takes 10,000IU per day. The bottle I purchased recommends 2,000IU per day. Get your blood work done people.

Source for the Fauci claim? I've seen a claim of 6000 (not sourced properly), the RDA is 600, I couldn't find even a dubious source for 10000 and all decent sources didn't give a dose at all.

Given that 10000 is considered more than the maximum safe amount by many health authorities, I doubt Fauci would say he's taking that much even if he did.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#126

Post by the-dude »

roel_v wrote: post #94
monetus wrote: post #34

Earlier quoted context omitted.

For reference: The level of toxicity listed in your link is 60,000IU per day. Fauci said he takes 10,000IU per day. The bottle I purchased recommends 2,000IU per day. Get your blood work done people.

I always see Americans (apologies for making assumptions if you're not) throw around blood testing like it's something trivial and casually done. Here in the Netherlands, it takes a real medical indication and some pushing of a doctor to get any testing done. Alternatively, you use a private testing company that costs 200 to 400 euros for a comprehensive screening. Question to the public in various countries - how ea…

This is not accurate : although I will not deny Dutch doctors are weary of preventive testing, it depends on your doctor.

My current doctor agrees to get my blood tested quite easily ( I don't have very serious issues ). It is not expensive either. When symptoms improved, we agreed let's test again, see where we are.

My previous doctor however, was very adverse. I left him because of this.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#127

Post by keeganpoppen »

bgilroy26 wrote: post #57
Scoundreller wrote: post #47

Earlier quoted context omitted.

We could fortify beer and Coca Cola with it. While it’ll be on the label, I bet 9/10 people can’t rhyme off what is fortified. (Around here, it’s salt, milk, flour and cereals that get fortified). Dunno where fluoride fits, but that too.

You belong to an interesting language isolate with whoever wrote this article: SUNNY VALLI CRAG http://3.251.20.7/log-details/?log_id=490&y=2009 I was puzzled by your phrase "can't rhyme off". Google returns very few instances that are not related to spontaneous spoken word poetry (which is likely an example of convergent evolution). After poking around a bit, it seemed as though I had heard a similar phrase before "…

what a fun phrase. wiktionary says canada: https://en.wiktionary.org/wiki/rhyme_off

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#128

Post by tgsovlerkhgsel »

cassepipe wrote: post #122
ve55 wrote: post #5

It's worth noting that vitamin D has a lot of high-confidence but low-effect results going for it, including a lot of strong meta-analysis over many health outcomes. What I mean by this is that it usually seems to conclusively either do something beneficial, but minor, almost nothing in the case of many studies, and in the case of some others, something very beneficial (as we've seen a few of in relation to covid rec…

"The non-financial costs such as side effects or potential adverse effects are practically non-existent as well." This not accurate. I remember that there was an article on the front page of Hacker News an article that explain that Vitamin D is actually a hormone and telling the story of woman that had been prescribed high level of supplementation that could not talk anymore. It had something to do with her calcium i…

I assume they were talking about supplementation at normal supplementation levels, not 10x - 100x that.

As someone pointed out below, if you drink 10x-100x the recommended amount of water, you're likely to have adverse effects (almost certainly including death at 100x) too.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#129

Post by distant_hat »

roel_v wrote: post #94
monetus wrote: post #34

Earlier quoted context omitted.

For reference: The level of toxicity listed in your link is 60,000IU per day. Fauci said he takes 10,000IU per day. The bottle I purchased recommends 2,000IU per day. Get your blood work done people.

I always see Americans (apologies for making assumptions if you're not) throw around blood testing like it's something trivial and casually done. Here in the Netherlands, it takes a real medical indication and some pushing of a doctor to get any testing done. Alternatively, you use a private testing company that costs 200 to 400 euros for a comprehensive screening. Question to the public in various countries - how ea…

In India, I can get almost any blood test with no requirement to get a prescription. The phlebotomist will even come home to collect the blood sample. The prices are fairly reasonable and most tests will be under $20.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#130

Post by abainbridge »

cassepipe wrote: post #122
ve55 wrote: post #5

It's worth noting that vitamin D has a lot of high-confidence but low-effect results going for it, including a lot of strong meta-analysis over many health outcomes. What I mean by this is that it usually seems to conclusively either do something beneficial, but minor, almost nothing in the case of many studies, and in the case of some others, something very beneficial (as we've seen a few of in relation to covid rec…

"The non-financial costs such as side effects or potential adverse effects are practically non-existent as well." This not accurate. I remember that there was an article on the front page of Hacker News an article that explain that Vitamin D is actually a hormone and telling the story of woman that had been prescribed high level of supplementation that could not talk anymore. It had something to do with her calcium i…

This case, I think: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313753/

It looks like she was getting 600,000 IU injections every week for three months. That's 85,714 IU per day. The NHS recommends maintenance does of 400 IU per day, others recommend up to 2000 IU.

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