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Fathers’ choices may be packaged and passed down in sperm RNA

quantamagazine.org

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Re: Fathers’ choices may be packaged and passed down in sperm RNA

#111

Post by pcl »

sigmoid10 wrote: post #107
larusso wrote: post #104

Earlier quoted context omitted.

I agree. The example with Nicotine intake having a somewhat positive effect on the children feels too wild at the money. Think of all the kids of the 60th and 70th. They must be immune to most toxins ;). Yes I take this example to the extreme. I also feel that this could maybe contradict what we learned from evolution theory. Why would it take so long for a given treat to establish itself. Maybe I mix too much into o…

>I also feel that this could maybe contradict what we learned from evolution theory. It doesn't, but the article doesn't go into this detail, so people unfamiliar with the field wouldn't understand why. The keyword is epigenetics. I.e. how certain genes become activated or deactivated through behaviour and/or environmental influences. But the DNA sequence itself remains unaltered. So no evolution necessary. There are…

> ”They will not persist across many generations though”

Why not? Is there some tempering mechanism on epigenetic transfer? I could imagine that some sperm-conferred epigenetic markers could continue down the male descendants unbroken.

Re: Fathers’ choices may be packaged and passed down in sperm RNA

#113

Post by schiffern »

larusso wrote: post #104
jibal wrote: post #68

> “This study shows that paternal exercise can confer benefits — enhanced endurance and metabolic health — to offspring,” So good habits can be good for offspring. > For instance, mouse fathers exposed to nicotine(opens a new tab) sire male pups with livers that are good at disarming not just nicotine but cocaine and other toxins as well. So bad habits can be good for offspring. > “We just don’t have really any under…

I agree. The example with Nicotine intake having a somewhat positive effect on the children feels too wild at the money. Think of all the kids of the 60th and 70th. They must be immune to most toxins ;). Yes I take this example to the extreme. I also feel that this could maybe contradict what we learned from evolution theory. Why would it take so long for a given treat to establish itself. Maybe I mix too much into o…

  >Think of all the kids of the 60th and 70th. They must be immune to most toxins ;).
60th and 70th what?? :)

But seriously though, "immune" is a humorous exaggeration, but I'm not sure we have data to rule out the idea that this cohort has increased tolerance to some environmental toxins.

So it's possible the level of harm we see today is already "post-" this protective effect, if any.

Re: Fathers’ choices may be packaged and passed down in sperm RNA

#114

Post by dotancohen »

schiffern wrote: post #113
larusso wrote: post #104

Earlier quoted context omitted.

I agree. The example with Nicotine intake having a somewhat positive effect on the children feels too wild at the money. Think of all the kids of the 60th and 70th. They must be immune to most toxins ;). Yes I take this example to the extreme. I also feel that this could maybe contradict what we learned from evolution theory. Why would it take so long for a given treat to establish itself. Maybe I mix too much into o…

>Think of all the kids of the 60th and 70th. They must be immune to most toxins ;). 60th and 70th what?? :) But seriously though, "immune" is a humorous exaggeration, but I'm not sure we have data to rule out the idea that this cohort has increased tolerance to some environmental toxins. So it's possible the level of harm we see today is already "post-" this protective effect, if any.

  > 60th and 70th what?? :)
GP means that from the 1960s to the 1970s many people in his part of the world were deliberately putting "toxins" in their bodies.

He means that the hippie generation and disco generation took a lot of drugs.

Re: Fathers’ choices may be packaged and passed down in sperm RNA

#115

Post by yreg »

tacitusarc wrote: post #42
dietr1ch wrote: post #38

Earlier quoted context omitted.

> I told the waitress “you too” wrt to her telling me to enjoy my meal. That's not too bad unless you are in a group and they make fun of you right away, but it's a fumble that you can fix and start a good play if you don't just get super nervous. Laugh it off, ask her if it's not the first one, ask her to join, even if you know she's actually working and can't. I've never done any improv, but it seems like something…

Nah just yell “switcheroo!” then grab her outfit and suddenly you're the waitress and she’s the diner with a meal to enjoy.

Is this a lucid dream?

Re: Fathers’ choices may be packaged and passed down in sperm RNA

#116

Post by schiffern »

dotancohen wrote: post #114
schiffern wrote: post #113

Earlier quoted context omitted.

>Think of all the kids of the 60th and 70th. They must be immune to most toxins ;). 60th and 70th what?? :) But seriously though, "immune" is a humorous exaggeration, but I'm not sure we have data to rule out the idea that this cohort has increased tolerance to some environmental toxins. So it's possible the level of harm we see today is already "post-" this protective effect, if any.

> 60th and 70th what?? :) GP means that from the 1960s to the 1970s many people in his part of the world were deliberately putting "toxins" in their bodies. He means that the hippie generation and disco generation took a lot of drugs.

I figured, just a joke playing off their typo (hence the smiley).

There were plenty of non-"drug" toxins people were exposed to where levels peaked around that time — leaded gasoline, early food contact plastics with unsafe additives, pesticides that are now banned, etc. But thanks Nancy Reagan. ;)

Re: Fathers’ choices may be packaged and passed down in sperm RNA

#117

Post by andrepd »

ralusek wrote: post #16
websiteapi wrote: post #9

assuming this is true, perhaps it's best to freeze sperm regularly with labels that way if you go off the deep end you can snapshot quite literally your best self? some possible times - right before college, right after college, after you meet someone you think you'd marry (but before you do), after marriage. seems like a neat premise for a sci fi novella.

If my quicksave/quickload savescumming is to be observed, I’d be pining for that sperm from before I told the waitress “you too” wrt to her telling me to enjoy my meal.

> saves cumming

Re: Fathers’ choices may be packaged and passed down in sperm RNA

#119

Post by DANmode »

jibal wrote: post #68

> “This study shows that paternal exercise can confer benefits — enhanced endurance and metabolic health — to offspring,” So good habits can be good for offspring. > For instance, mouse fathers exposed to nicotine(opens a new tab) sire male pups with livers that are good at disarming not just nicotine but cocaine and other toxins as well. So bad habits can be good for offspring. > “We just don’t have really any under…

You took a left-turn:

Nicotine is on-par with caffeine in isolation.

It’s the rest of the crap in smokes and vapes to be concerned with.

I was surprised to learn nicotine is used by functional doctors to treat CFS-adjacent conditions, and the mechanisms therein.

Re: Fathers’ choices may be packaged and passed down in sperm RNA

#120

Post by vbezhenar »

dotancohen wrote: post #114
schiffern wrote: post #113

Earlier quoted context omitted.

>Think of all the kids of the 60th and 70th. They must be immune to most toxins ;). 60th and 70th what?? :) But seriously though, "immune" is a humorous exaggeration, but I'm not sure we have data to rule out the idea that this cohort has increased tolerance to some environmental toxins. So it's possible the level of harm we see today is already "post-" this protective effect, if any.

> 60th and 70th what?? :) GP means that from the 1960s to the 1970s many people in his part of the world were deliberately putting "toxins" in their bodies. He means that the hippie generation and disco generation took a lot of drugs.

Humans put toxins into their bodies for the entire history of humankind.
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