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Weight loss jabs: What happens when you stop taking them

bbc.com

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Re: Weight loss jabs: What happens when you stop taking them

#111

Post by uxjw »

isoprophlex wrote: post #13
belter wrote: post #2

TLDR: "...evidence so far suggests that, between one and three years after stopping the medication, people will see a "significant proportion of weight" go back on...Somewhere in the region of 60 to 80% of the weight that you lost will return..."

Taking recovered drug addicts and placing them in a situation where everyone's using all the time would probably lead to equally bad outcomes. Our food is too rich in calories, too abundantly available, and too addictive for most people.

Yes, the cheap engineered "foods" don't help, and they're everywhere. This part of the article really hit home:

> He is worried that without additional support for people making the transition, society's unhealthy relationship with food means little will change.

> "The environment that people live in needs to be one that promotes health, not weight gain.

Also generic versions of Ozempic are coming to Canada soon: https://www.cbc.ca/news/health/ozempic-generic-canada-weight...

Re: Weight loss jabs: What happens when you stop taking them

#112

Post by premiumLootBox »

manmal wrote: post #46
hamandcheese wrote: post #18

Earlier quoted context omitted.

"Ozempic face" is actually just "unhealthy rapid weight loss face". Ozempic makes it easier to starve yourself, but that isn't how it's supposed to be used.

It’s also accelerated muscle loss, even heart tissue. I‘m not saying it’s not worth it, but this should be kept on the radar for sure.

[dead]

Re: Weight loss jabs: What happens when you stop taking them

#113

Post by array_key_first »

xorcist wrote: post #107
jmward01 wrote: post #8

Other medications become lifelong medications but without this level of scrutiny. I am 100% in favor of finding a more permanent treatment, but switching blood pressure meds, and cholesterol meds, and other daily meds for a single once a week med is a massive improvement, especially since the all source mortality data keeps rolling in showing the efficacy here is orders of magnitude better than all the other medicati…

> society views being fat as a moral failing This is just as weak as a counter argument. If every argument that concludes that lifestyle changes are necessary, in most situations and for most patients, are just written off as some sort of moral high ground and not necessarily something to take seriously, then what do we have left? Is there seriously no functional difference between healing a broken bone and getting s…

There's a common misunderstanding that medication and lifestyle changes are two separate things, and we should do one or the other, with medication being the "easy way" out.

No. The way GLP-1 drugs work is by lifestyle changes. People on GLP-1 agonists will, on average, eat smaller portions, are more inclined to eat healthier food, and will even exercise more.

If you take GLP-1s and don't do the lifestyle changes, they don't work. So are these drugs useless? No. They make the lifestyle changes more attainable. In your smoking example, it's similar. We have cessation drugs, I know because I've used them. No, they don't magically make you stop smoking. But they do make it easier.

We need to rewrite how we view these drugs. They don't take away your power, your strength. No, they help you find it. You had the strength all along, but these are tools to help you exercise it.

Re: Weight loss jabs: What happens when you stop taking them

#114

Post by array_key_first »

tartoran wrote: post #49
hamandcheese wrote: post #18

Earlier quoted context omitted.

"Ozempic face" is actually just "unhealthy rapid weight loss face". Ozempic makes it easier to starve yourself, but that isn't how it's supposed to be used.

Taking Ozempic also drops a lot of muscular mass and that ozempic face look totally makes sense. There's no free lunch or wonder drug. While it's effective at weight loss it has a lot of unwanted side effects. And when stopping the drug the weight gain comes back so not sure if it's worth it.

> Taking Ozempic also drops a lot of muscular mass and that ozempic face look totally makes sense.

No, it doesn't, weight loss does this. I've lost weight before via starving and even as a man, all my muscle went poof. If you look at someone like Ariana Grande, who clearly is anorexic, here arms are like sticks and here face looks tautly stretched over her bones.

This is just what happens when you starve your body of nutrients. Your muscles are some of the first to go because they're the least vital. Your organs and brain are much, much more important. Your body will have no issue taking your muscle away to give it to your organs. Regardless of ozempic.

Re: Weight loss jabs: What happens when you stop taking them

#115

Post by array_key_first »

AaronAPU wrote: post #33
jmward01 wrote: post #8

Other medications become lifelong medications but without this level of scrutiny. I am 100% in favor of finding a more permanent treatment, but switching blood pressure meds, and cholesterol meds, and other daily meds for a single once a week med is a massive improvement, especially since the all source mortality data keeps rolling in showing the efficacy here is orders of magnitude better than all the other medicati…

But it is factually true that it’s a matter of willpower, no amount of reframing it is going to change that. It’s not like others like myself, currently on a cut cycle, don’t experience hunger. The idea that we are just “lucky” ignores all the willpower and discipline we fight through to do it ourselves. I’ve eaten about 800 calories today and it is 4pm. Just finished 90 minutes on the indoor bike. My stomach feels h…

> But it is factually true that it’s a matter of willpower, no amount of reframing it is going to change that.

Okay... how?

You can't just make incredibly bold claims, say "it's a fact!" and then move on. No, you have to back them up otherwise you're just a bullshitter.

I don't know what other people, anyone else, is feeling. How do I know my hunger is their hunger?

Re: Weight loss jabs: What happens when you stop taking them

#116

Post by array_key_first »

thefz wrote: post #101
AaronAPU wrote: post #33

Earlier quoted context omitted.

But it is factually true that it’s a matter of willpower, no amount of reframing it is going to change that. It’s not like others like myself, currently on a cut cycle, don’t experience hunger. The idea that we are just “lucky” ignores all the willpower and discipline we fight through to do it ourselves. I’ve eaten about 800 calories today and it is 4pm. Just finished 90 minutes on the indoor bike. My stomach feels h…

You can't make this point here without getting down voted to oblivion. I know many ultra endurance runners and they are all in very good - healthy - shape. The only thing they all have in common is that they are very, very disciplined people.

> I know many ultra endurance runners and they are all in very good - healthy - shape. The only thing they all have in common is that they are very, very disciplined people.

Right, but are you not seeing that this is orthogonal?

Meaning, is it that running MAKES YOU disciplined, or rather that people who are already predisposed to being disciplined are more likely to be runners? This says nothing about the genetic component of it.

And you would have to be born yesterday to truly think there is no genetic component. Even with alcoholism, we know it's hereditary. We know when it comes to compulsions there is a genetic component. This is not opinion, this is fact. We know this.

But specifically with food habits, you truly believe this is not the case? Do you not see how incredibly bold of a claim that is? How atypical, how surprising, that would be?

I'm not saying that some people are blessed and some are not. Everyone has the power to change their lives. But I AM saying that it's not the same for everyone. From the beginning, I have known some things come easier to some people. I thought this was common knowledge, a part of the human condition we were all aware of.

Re: Weight loss jabs: What happens when you stop taking them

#117

Post by array_key_first »

thefz wrote: post #104
sergiosgc wrote: post #103

Earlier quoted context omitted.

No. The article explains they do not cure the underlying issue, whatever it is. We have many such drugs, widely accepted as safe and effective.

So they are not effective.

Are you not listening or...?

I took chemotherapy for cancer treatment, and it was very effective. Chemo is not a root-cause solution. It's a shotgun solution, a hammer even. It just kills cells that look like cancer. It doesn't stop cells from being cancerous, or turn cancerous cells back into normal cells. It's also carcinogenic, meaning it actually causes cancer. I am now much more likely than the general population to develop another cancer.

But it also saved my life. We do not measure effectiveness of medicine by if you think it's morally just. Nobody cares what you think, actually. We measure it in the real world, by if it works.

Re: Weight loss jabs: What happens when you stop taking them

#118

Post by array_key_first »

paulpauper wrote: post #65
randallsquared wrote: post #44

Earlier quoted context omitted.

> outright thermodynamics deniers I've heard people say this before, but when reading those arguments it mostly turns out to be people who think there's something more complicated going on with digestion, excretion, or metabolism such that eaten calories are more efficiently used for some, and burned off or passed through without full processing to some degree for people who self-reportedly "can't gain weight".

Right, the body can choose to either convert surplus calories to fat or waste heat. The latter could explain how some individuals are much more resistant to weight gain than others. This is also supported by overfeeding studies, in which controlling for relevant factors, some people gain much more fat on a deliberate calorie surplus than others.

It should also just be obvious to people. The body, of course, has a choice in how it spends it's energy.

There have been studies on ababolics, synthetic testosterone, that demonstrate this. Taking steroids and doing absolutely nothing leads to more fat loss and more muscle gain than not taking steroids and working out. Which... yeah duh.

But people will still deny this, because of the implications. We all have different baselines, and nobody likes to hear that they got lucky in some ways. Everyone wants to believe the world and human condition is perfectly fair, so they feel that they deserve what they have.

Re: Weight loss jabs: What happens when you stop taking them

#119

Post by array_key_first »

true2octave wrote: post #89
paulpauper wrote: post #66

Earlier quoted context omitted.

the problem is, obese or formerly obese people clan eat a lot of anything before the full feeling sets in, no matter what. Eggs, chicken..does not matter.

It takes time and discipline to make the stomach smaller I was pre-diabetic at 100kg and went down to 70kg over a year of low carb diet and intermittent fasting It’s a daily struggle trying to NOT eat until literally feeling pain in the belly, and even then, I know if I wait 30 minutes more I can keep eating

> It’s a daily struggle trying to NOT eat until literally feeling pain in the belly, and even then, I know if I wait 30 minutes more I can keep eating

Yes, but this is sort of the point. If we can make it not a daily struggle, probably a lot more people would be successful.

Generally, I think the solution of "just suffer" is a bad one. If people's solution requires a certain amount of pain, it's probably just a suboptimal solution, and we can do better.

Re: Weight loss jabs: What happens when you stop taking them

#120

Post by array_key_first »

sixtyj wrote: post #23
blindriver wrote: post #10

Earlier quoted context omitted.

It's not hyped. It's the most effective way I've seen the people around me lose weight. Some of them have lost a tremendous amount of weight very quickly. But a know a couple of them that went off it and the weight came back pretty quickly. It really is just a suppression of hunger, nothing more than that.

It can be hyped because jabs bring immediate results. And it can be prescribed by almost every doctor so number of people who can report is big, and therefore visible results can be further disseminated (hyped). But… treatment is working. Question is at what cost. If something is too good to be true, one has to ask what is behind it. But perhaps it is a similar situation to when antibiotics were invented.

> one has to ask what is behind it.

The human body is stupid and makes a lot of mistakes. It's very obvious to me that our bodies and minds were not built for their current environment.

When someone's brain has a bug in which is has seizures, we do not ask them "what's behind" their epilepsy medication. No, we understand their brain has a problem that should be fixed. There is no ulterior perspective, some secret hidden ability they might possess. It's just bad.

But when it comes to food, we forget this is how we view things. In it's place comes moralizing.

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