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Researchers find Alzheimer's-like brain changes in long Covid patients

uknow.uky.edu

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Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#111

Post by ipsum2 »

dyauspitr wrote: post #106
H8crilA wrote: post #96

ME/CFS is seriously underinvested. I don't really understand why, any drug that makes a noticeable difference here will be a guaranteed money printer. There are millions of people suffering total disability, many in developed countries that have well funded medical insurance. Compare that to depression (which it only superficially resembles): many SSRIs, SNRIs, multiple "schools" of psychotherapy, neuroleptics, lithi…

You can probably take a low dose of adderall to alleviate atleast the symptoms.

I tried this, it didn't work. Did you have success with this?

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#112

Post by edejong »

I thought this was already well known. A study in 2021 [1] found this relationship. However, it is good to keep people informed because it seems we are letting a potentially severely disrupting disease shred our society to bits.

From 2021: “Biological markers of brain injury, neuroinflammation and Alzheimer’s correlate strongly with the presence of neurological symptoms in COVID-19 patients.”

[1] https://aaic.alz.org/releases_2021/covid-19-cognitive-impact...

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#113

Post by patrickdavey »

I visited two friends recently when I was back in Ireland. They had both been fit climber/orienteering types. Both now incapacitated with long covid. Both had been vaccinated.

I went for a very short very slow walk with one of them. She wears a fancy Garmin which beeps when her heart rate goes over 100bpm. We walked for 15 mins and it went off.

I really hadn't realised quite how real and quite how incapacitating long covid is.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#114

Post by OJFord »

goochphd wrote: post #62
OJFord wrote: post #41

Earlier quoted context omitted.

I mean when you write 'UK researchers find', especially to a global audience (which UoKentucky PR dept may not particularly have but HN does (Hello from the ( the !) UK)) that it sounds more like the country UK than the.. no offence intended but not exactly world renowned university. (I've heard of Kentucky, probably my first time hearing of its university in its own right - though I might have assumed it had one.)

I wouldn't read too much into it. UK is one of my alma maters. Everyone in that area of the US means "University of Kentucky" when they say "UK". It isn't a dig at the United Kingdom nor is it (I assume) an attempt to gain undue credibility by associating with the country. For the people there, UK as the University is simply the first order association for that acronym, rather than what is to them a faraway country t…

> I wouldn't read too much into it.

I don't think I am? I'm just agreeing the title should be different here, and it has now changed so either the submitted or a mod agreed.

> Everyone in that area of the US means "University of Kentucky" when they say "UK". It isn't a dig at the United Kingdom nor is it (I assume) an attempt to gain undue credibility by associating with the country. For the people there, UK as the University is simply the first order association for that acronym, rather than what is to them a faraway country that has no bearing on their day-to-day lives.

Right, that's what I meant about audience, and it making sense for the UoK's PR dept.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#115

Post by pizza »

dyauspitr wrote: post #106
H8crilA wrote: post #96

ME/CFS is seriously underinvested. I don't really understand why, any drug that makes a noticeable difference here will be a guaranteed money printer. There are millions of people suffering total disability, many in developed countries that have well funded medical insurance. Compare that to depression (which it only superficially resembles): many SSRIs, SNRIs, multiple "schools" of psychotherapy, neuroleptics, lithi…

You can probably take a low dose of adderall to alleviate atleast the symptoms.

From what I understand about ME/CFS, both post-exertional malaise and dysautonomia are symptoms- seems like stimulant use could make those things go either way

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#116

Post by ben_w »

genewitch wrote: post #90
_whiteCaps_ wrote: post #2

I had strange symptoms post-Covid infection - my ability to recognize faces was very distorted and it seemed like everyone was familiar to me. It was like everyone I saw was an old high school acquaintance or maybe a celebrity, and I would get anxious because I didn't remember their name.

there was publications about viruses "causing the host to be more outgoing/in public" in the lead-up to the part of the disease where you're laid up with fluids leaking out of every orifice. I'm fairly certain some flu and iirc sars-ncov-2 were found to display this secondary (or tertiary) effect. So you "catch" a flu. Before you know you've caught it, suddenly you want to go out to dinner, or go to a meetup of frien…

I have a suspicion that, for similar reasons, STDs would also be likely to make people hornier.

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#117

Post by RagnarD »

This isn't too big of a surprise when you look at the evidence that Alzheimer's, in general, is essentially a chronic viral disease of the brain. Ruth Itzhaki in particular has spent much of her career researching the connection (https://research.manchester.ac.uk/en/persons/ruth.itzhaki).

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#118

Post by carlmr »

Etheryte wrote: post #108
ingonealan3 wrote: post #85

I thought I was depressed, but recently realised that I’m actually feeling off because of long COVID symptoms. The brain fog is pretty much constant, and I’m definitely more forgetful and confused than I used to be. There are some cardiac symptoms as well, but those interfere less with my day to day. I’d love to find a way out of this state, but it seems that my doctor doesn’t keep up with the latest research, and do…

I have a similar experience, albeit with a different set of symptoms. I've been active and athletic all my life, never a problem with my blood pressure, after Covid I now permanently have high blood pressure and need to treat for it. All the doctors I've seen tell me that no, Covid doesn't do that, even though there's a clear cut line of before and after.

>All the doctors I've seen tell me that no, Covid doesn't do that

"Strong arguments support the thesis that, through various mechanisms, COVID-19 infection can contribute to the development of hypertension." [1]

At least some of the literature points in that direction. Have your doctors read the literature and concluded it's not a thing or did they just wing it because Googling is hard?

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10856065/

Re: Researchers find Alzheimer's-like brain changes in long Covid patients

#120

Post by hypertele-Xii »

profsummergig wrote: post #67

My Covid "Toxo" hypothesis. Hear me out. Cat poop has something in it ("Toxo") that makes mice less afraid of cats. Win for cats. I see so much scientifically-unsound* anti-vaxx hysteria from people who used to be otherwise quite intelligent and rational, that I suspect that Covid has done a number on them (like "Toxo" does a number on mice). * IMHO, there can be rational hesitation to vaxx (Precautionary Principle,…

I'm not against vaccination. What is vaccination? An injection of deactivated bits of the disease into the bloodstream so the immune system can identify and begin producing antibodies against the disease prior to actual infection.

I'm against COVID "vaccines". What are COVID "vaccines"? An injection of mRNA genetic material that spreads around the body and reprograms your own cells to manufacture bits of the disease, so the immune system can blah blah etc.

Now please explain to me, why is the mRNA experimental gene therapy a required component of vaccination? Why couldn't they just inject bits of the virus like literally every single vaccine has worked since their invention? Why did we need to reprogram healthy people's cells to manufacture spike proteins that are like tiny little knives stabbing them from the inside, forever?

Well because vaccinating the population against the disease was never the goal. The goal was to push a mandatory genetic experiment and see if people react. They didn't. So get ready for your next round of mandatory gene therapy under the guise of "vaccination"!

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